2012, volume 8
Assessment level of anxiety and depression in patients with multiple sclerosis
Heading: Neurology Article type: Original article
Authors: Lukina E.V., Kusnetsova D.E.
Organization: Saratov State Medical University
In patients with multiple sclerosis observed polymorphism of the emergency psychiatric disorders with a wide range of psychopathological phenomena — from neurotic and personality disorders to psychotic states and epileptiform syndrome. However, the problems of mental health problems in people with MS for a long time little attention was paid. The aim of our study was to analyze the level of anxiety and depression severity in patients with multiple sclerosis. According to this objective have been identifed objectives of the study: to determine the level of depression and anxiety in MS patients according to sex, age, course, duration of disease. For our work was selected group of patients with documented diagnosis of multiple sclerosis, Charles Poser criteria, consisting of 79 persons, with a disease duration of more than 2 years. We used a specially designed questionnaire, which included a table to assess complaints, anamnesis, the neurological status of the patient, and standard questionnaires (test anxiety, Taylor Depression Scale Research psychoneurology them. Spondylitis, the index of overall psychological well-being). The study found that mood disorders such as anxiety, depression, often occurs in patients with multiple sclerosis. However, they are expressed in groups of patients receiving and not receiving DMD, in many ways. Thus, it should be recommended Vat practical neurologists in the treatment of multiple sclerosis patients to pay attention to whether or not they have a certain range of mental disorders, and above all, anxious-depressive syndrome, which is in need of medical and non-pharmacological correction.
Changes in the trigeminal nerve under the infuence of cortexin in patients with chronic generalized periodontitis
Heading: Neurology Article type: Original article
Authors: Lepilin A.V., Sholomov I.I., Erokina N.L., Soyher M.G., Nozdrina V.D., Bisultanov H.W.
Organization: Saratov State Medical University, Center for Interdisciplinary Dentistry and Neurology, Moscow
Purpose: correction of violations in the trigeminal nerve in patients with chronic generalized periodontitis. Material and methods. A clinical examination and study of the functional activity of the trigeminal nerve in 160 patients with chronic generalized periodontitis. Results. Revealed the presence of various degrees of violations of the functional activity of the trigeminal nerve depending on the severity of the pathological process in periodontal tissues. Conclusion.Neuroprotective therapy in the treatment of patients with periodontal disease leads to normalization of the neurophysi-ology of the trigeminal nerve and promotes more rapid relief of the infammatory process in periodontal tissues.
Back pain: gender features
Heading: Neurology Article type: Original article
Authors: Kurushina O.V., Barulin A.E.
Organization: Volgograd State Medical University
The goal of the research is to study features of a back pain syndrome and its medicalization at men and women. There were 217 patients with a back pain being on treatment in neurologic department of the regional clinical hospital №1 (Volgograd). The results of the research indicate big prevalence of acute back pain syndromes at men, chronic ones — at women. Thus, women show big need for a medicalization of the pain, but men ask for a medical care less then women. As a result men feel considerable diffculties at the description of nature of algetic disorder.Conclusion. It is necessary to take into consideration the revealed gender features of patients with a back pain in the process of planning therapeutic actions.
MRI capabilities of diagnostics of multicentricity brain lesions
Heading: Neurology Article type: Review
Authors: Kondrat`eva O.A., Chekhonatskaya M.L., Priezshzeva V.N., Hmara T.G
Organization: Saratov State Medical University
Тhe problem of multicentricity brain damage is relevant in connection with the presence of many diseases, shown data of radiation syndrome. Timely detection of pathological processes allows to carry out adequate therapy from the early stages of the disease, which considerably improves the course and prognosis of the disease. The article presents some aspects of differential diagnostics of vascular, infammatory, infectious and hereditary diseases, shown multicen-tricity lesions of the substance of the brain MRI study.
THE POSSIBILITIES OF VERIFICATION OF SYPHILITIC AFFECTION OF THE NERVOUS SYSTEM
Heading: Neurology Article type: Review
Authors: Kolokolov O.V., Bakulev A.L., Kolokolova A.M., Abramova T.P.
Organization: Saratov State Medical University
We present modern laboratory methods of syphilis and neurosyphilis diagnostics. The question of verifcation of neurosyphilis form by using methods of neuroimaging and neurophysiology is discussed.
PATHOMORPHOSIS IN THE CLINICAL PICTURE OF NEUROSYPHILIS
Heading: Neurology Article type: Review
Authors: Kolokolova A.M., Kolokolov O.V., Abramova T.P.
Organization: Saratov State Medical University
For the last decade the clinical fndings of the neurosyphilis had changed. We report a review of literature where the information about the modern picture of the disease is described.
VISUAL DISTURBANCES IN PATIENTS WITH LATENT SYPHILIS
Heading: Neurology Article type: Short message
Authors: Kolbenev I.O., Kamenskih T.G., Kolokolov O.V., Bakulev A.L., Kolokolova A.M.
Organization: Saratov State Medical University
Цель: определить характер зрительных нарушений у больных латентным сифилисом, оценить возможности исследования зрительных вызванных потенциалов (ЗВП), оптической когерентной томографии (ОКТ) и лазерной конфокальной томографии (ЛКТ) в диагностике и уточнении формы нейросифилиса. Материалиметоды. Обследованы 133 больных скрытым сифилисом на предмет выявления признаков поражения нервной системы и органа зрения. Результаты. Рутинное офтальмологическое обследование позволяет обнаружить нарушения зрения у 48 % больных латентным сифилисом. При нейросифилисе наиболее часто встречается ангиопатия сетчатки и первичная атрофия дисков зрительных нервов. Исследование ЗВП, использование ОКТ и ЛКТ позволяют выявлять признаки поражения органа зрения в 66 – 79 % случаев латентного сифилиса, нередко — до появления симптомов и признаков заболевания. Заключение. Офтальмологическое обследование должно быть обязательным не только при установленном диагнозе «нейросифилис», но и во всех случаях латентного сифилиса.
CORRELATION OF PROGRESSION RISK OF FETOPLACENTAL INSUFFICIENCY WITH VEGETATIVE STATUS DISTURBANCE IN PREGNANT WOMEN
Heading: Neurology Article type: Original article
Authors: Kipchatova T.Yu., Chekhonatskaya M.L., Chernyshkova E.V., Chekhonatsky A.A.
Organization: Saratov State Medical University
Research Goal was to compare probability of risk progression of chronic fetoplacental insuffciency with various disturbances of vegetative nervous system (VNS) in pregnant women. Materials. Basic group consisted of 112 pregnant women with chronic fetoplacental insuffciency; control group included 73 women with physiological course of pregnancy and delivery. Status of VNS was determined with the purpose to estimate initial vegetative tone in various functional systems and forming concept of general vegetative status in the sample. Results. Presence of fetoplacental insuffciency in pregnant women was extensively associated with increase of sympathetic section tone and VNS lability. Occurrence frequency of critical indices of hemodynamics disturbances in the system mother- placenta-fetus revealed reliable correlation dependence on VNS lability and index of vegetative supply of activity. Conclusion. Pregnant women with fetoplacental insuffciency had 25 – 30 % increased tone and lability indices of VNS sympathetic section in contrast to physiological course of pregnancy. Progression of fetoplacental insuffciency was more often revealed in pregnant women in case of replacement of sympathicotonia by vagotonia, and against a background of high VNS lability and reactivity.
RARE EVENT OF THE ANEURYSMATIC DISEASE IS A DEVELOPMENTAL VARIATION OF KLIPPEL–TRENAUNAY SYNDROME
Heading: Neurology Article type:
Authors: Karas A.U., Kolokolov O.V., Zhukovskaya A.U., Grigorieva E.A.
Organization: Saratov State Medical University
The purpose is to present the event of the aneurysmatic disease within the polymorphism of Klippel–Trenaunay syndrome (KTS), that differs from classic forms with predominates of arteries’ lesion. Materials. The modern diagnostic of phacomatoses, including KTS, is based on physical examination. However, along with a combined lesion of skin, nervous system, internal organs, there is clinical polymorphism and delayed symptoms that hinders the verifcation of nosological entity. In the reported case the lack of objectivation of KTS’ manifestation became the cause of delayed diagnostic of aneurysmatic disease within the basic disease. Conclusion. The necessity of complex approaches in the studying of arterial hypertension and early detection of intracranial complications in patients with phacomatoses are determined by high level of intracerebral nontraumatic hemorrhage.
Comparative analysis of the results of various physical therapy techniques in the treatment of patients with primary open-angle glaucoma with chronic cerebral ischemia
Heading: Neurology Article type: Original article
Authors: Kamenskih T.G., Raigorodskij Y.М., Veselova E.V., Mishkina E.J., Kolbenev I.O., Lazarev М.S., Kamenskih I.D.
Organization: Saratov State Medical University
Aim of the study: to evaluate the effectiveness of the techniques of dynamic simultaneous transcranial magnetic therapy and resonance, and electrical stimulation, transcranial magnetic therapy and dynamic laser stimulation, magnetic simpatokorrektsii in the treatment of patients with primary open-angle glaucoma with chronic cerebral ischemia. Techniques. We observed 184 patients diagnosed with primary open-angle glaucoma who received different physical therapy techniques. Results. Patients treated with transcranial magnetic therapy and electrical stimulation or laser stimulation, in addition to improving visual function and improve the bioelectrical activity of the visual cortex, more pronounced than in other groups also observed the activation of the intraocular blood fow. Application of magnetic simpatokorrektsii allows for improvement of basic functional, electrophysiological and hemodynamic performance by reducing the activity of the sympathetic nervous system and reduce the vasopressor effect. Conclusion. Transcranial magnetic therapy in combination with electrical stimulation or laser stimulation is effective in the treatment of patients with POAG. In patients with primary open-angle glaucoma with chronic cerebral ischemia technique of magnetic sim-patokorrektsii compared with traditional methods of vasoactive therapy is more effective, which is manifested not only increase the visual functions, but also a decrease in cognitive impairment.