Saratov JOURNAL of Medical and Scientific Research

Features of blood lipid profile in low birth weight infants with different types of feeding

Year: 2019, volume 15 Issue: №2 Pages: 232-236
Heading: Pediatrics Article type: Original article
Authors: Kadymova I.I., Bochkova L.G., Eiberman A.S., Gumeniuk O.I., Kirilochev O.K.
Organization: Astrakhan State Medical University, Saratov State Medical University

The research goal is to study of blood lipid profile for different types of feeding in infants with low birth weight (LBW), very low birth weight (VLBW) and extremely low birth weight (ELBW) at birth, receiving breast milk or special mixes, to determine whether correction of their food. Material and Methods. The dynamic study of cholesterol (CS), triglycerides (TG), high-density lipoproteins (HDL) and low-density lipoproteins (LDL) was carried out depending on the type of feeding in low-weight infants of different weight categories. The concentration of these lipid components was determined using the test of Liquick Cor-CHOL; Liquick Cor-TG; CORMAY HDL DIRECT systems. Results. This study showed that newborns with extremely low birth weight with intrauterine growth retardation and newborns with very low birth weight had significantly lower levels of lipid profile than infants with low birth weight (CS — by 11-17%, TG — by 18-27%, HDL — by 33-47%, LDL— by 14%). Conclusion. Extremely low birth weight newborns with intrauterine growth retardation (IGR) and very low birth weight newborns need early correction of lipid metabolism throughout the neonatal period.

1 Peacock JL, Marston L, Marlow N, et al. Neonatal and infant outcome in boys and girls born very prematurely. Pediatr Res 2012; 71: 305-10
2 Jobe AH, «Miracle» extremely low birth weight ne-onates: examples of developmental plasticity. Obstet Gynecol 2010; 116: 1184-90
3 Veronica M, Guilfoy MD, Wright-Coltart S, et al. Expenditure in Extremely Low Birth Weight Infants Near Time of Hospital Discharge. J Pediatr2008; 153 (5): 612-15
4 Coletta JM, Bell SJ, Roman AS. Omega-3 Fatty Acids and Pregnancy. Rev Obstet Gynecol 2010; 3 (4): 163-71
5 Smith SL, Rouse CA. Docosahexaenoic Acid and the Preterm Infant. Matern Health Neonatol Perynatol 2017; 3: 22
6 Carlson SJ, Fallon EM, Kalish ВТ. The role of the ы-3 fatty acid DHA in the human life cycle. JPEN J Parenter Enteral Nutr 2013; 37 (1):15-22
7 Szajewska H, Makrides M. Is early nutrition related to short-term health and long-term outcome? Ann Nutr Metab 2011; 58(1):38-48
8 Bobicski R, Mikulska M. The ins and outs of maternal-fetal fatty acid metabolism. Acta Biocheim Pol 2015; 62 (3): 499-507
9 Slusher T, Vaucher Y, Zamora T, Feeding CB. Fluids in the Premature and Sick Newborn in the Low-Middle Income Countries. Contemp Pediatr2012; 2: 29-56
10 Dutta S, Singh B, Chessell L, Wilson J, et al. Guidelines for Feeding Very Low Birth Weight Infants. Nutrients 2015 Jan; 7(1): 423-42
11 Maslovskaya AA. Features of lipid metabolism in children. Journal of the Grodno State Medical University 2010; 2: 12-15
12 Perepelitsa SA. Breach of lipid metabolism in newborn infants in the early neonatal period. General Reanimatolo-gy 2018; 14 (2): 13-24.

2019_02_232-236.pdf275.11 KB

No votes yet