Saratov JOURNAL of Medical and Scientific Research

Saratov State Medical University

www.sgmu.ru

Evidence of the safe period intravitreal tamponade by perfluorodecalin in clinical practice

Year: 2018, volume 14 Issue: №4 Pages: 862-866
Heading: Ophtalmology Article type: Original article
Authors: Arslanov G.M., Aznabaev В.М., Mukhamadeev T.R., Dibaev T.I.
Organization: Saratov State Medical University, The Eye Clinic «Zrenie» (Saint Petersburg)
Summary:

 Purpose: to perform clinical testing of perfluorocarbon liquid on the basis of perfluorodecalin with the possibility of intravitreal postoperative tamponade in patients with vitreoretinal pathology and explain the effectiveness of this practice. Material and Methods. Were evaluated anatomical and clinical results of vitrectomy with PFCL intravitreal tamponade in 105 (113 eyes) patients with severe vitreoretinal pathology. Three observation groups were distinguished: group I (in-traoperative and postoperative intravitreal tamponade by perfluorodecalin, national sample); group II (only intraopera-tive use of perfluorodecalin, foreign sample); group III (only intraoperative use of perfluoro-1.3- dimethylcyclohexane). Results. Retinal attachment in the group of patients with postoperative intravitreal tamponade was 97.1% (visual acuity increased in 71.5% cases). All cases of failure or redetachment, postoperative complications and cataract progression did not have a statistically significant association with postoperative intravitreal tamponade as risk factor (x2=0,316; X2=0,068; x2=0.061; x2=0.403, p>0.05). Conclusion. Clinical testing of perfluorocarbon liquid intravitreal tamponade on the basis of perfluorodecalin in patients with vitreoretinal pathology showed high anatomical and clinical results with a high probability of retinal attachment.

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The analysis of microcirculation parameters of the macular area after ultrasonic vitrectomy using optical coherence tomography-angiography

Year: 2018, volume 14 Issue: №4 Pages: 856-862
Heading: Ophtalmology Article type: Original article
Authors: Aznabaev В.М., Dibaev T.l., Ismagilov T.I..
Organization: Saratov State Medical University, ZAO Optimedservis
Summary:

Purpose: to analyze the parameters of the microcirculation of the macular area in patients operated on by the method of ultrasound vitrectomy 25G for idiopathic through macular opening (IMO) and epiretinal fibrosis (ERF). Material and Methods. ОСТ angiograms of 35 patients operated on by ultrasound vitrectomy for idiopathic through macular opening (IMO) and epiretinal fibrosis (ERF) before and for 3 months after surgery were analyzed. The following parameters of microcirculation of the retina were investigated: the area of the foveal avascularzone (FAZ), the density of the foveal vessels in the ring 300 urn around the FAZ, the density of the vessels in the superficial and deep capillary networks of the retina. Results. The FAZ area with IMO decreased within 3 months, while with ERF an increase in this parameter was recorded (p<0.05). In the superficial capillary network in both pathologies there was a decrease in the density of the vascular pattern (p<0.05), in IMH there was a tendency to recovery to the pre-op values. The deep capillary network was characterized by decrease of vascular pattern density to 1 month with following increase to 3 month (p<0.05). Conclusion. Features of the dynamics of the parameters of the microcirculation of the macular area in different periods of the postoperative period largely depend on the nature of the pathology, the stress response of the tissue to the operative traumaand the degree of recovery of the vascular pattern of the retinal neuroepithelium in the superficial and deep capillar networks.

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To the memory of Professor Sergey Rudolfovich Utz

Year: 2018, volume 14 Issue: №4 Pages: 779-781
Heading: Dermatovenerology Article type:
Authors: Zavyalov Al, Shnaider DA, Bakulev AL.
Organization: Saratov State Medical University
Summary:

The article is devoted to medical, scientific, pedagogical and public activity of S. R. Utz — a prominent scholar, dermatologist, chief physician of the clinic of skin and venereal diseases, Professor of the Saratov State Medical University.

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95 years on guard for health: from venereal offices to University clinic of dermatovenerology and cosmetology

Year: 2018, volume 14 Issue: №4 Pages: 773-779
Heading: Dermatovenerology Article type:
Authors: Schneider D.A., Bakulev A.L., Sherstobitova L.A., Martynova V.V..
Organization: Saratov State Medical University, SEH «Saratov regional dermatovenerologic dispensary»
Summary:

The article presents information about the establisment and development of the Saratov Regional Clinical Skin and Venereal Dispensary, the most prominent representatives of the dispensary, the main directions of scientific, educational and therapeutic activities. The role of the dispensary in the development of health education, prevention and improvement transmitted infections and infectious skin diseases is shown.

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Modern domestic cosmetics in combined treatment of scalp conditions

Year: 2018, volume 14 Issue: №4 Pages: 769-773
Heading: Dermatovenerology Article type: Original article
Authors: Shnaider D.A., Guskova O.P., Gorbenko A.V., Ivanov S.D.
Organization: Saratov State Medical University
Summary:

Objective: to evaluate effectiveness, safety and feasibility of using modern domestic ASD-containing liposomal cosmetics (all type shampoo and balm for dry scalp) in combined treatment of psoriasis patients with scalp involvement. Material and Methods. Sixty three patients (35 women and 28 men) with disseminated guttate-plaque psoriasis with scalp involvement were observed in Saratov Regional Clinical Dermatovenerologic Dispensary. The disease was in the stage of progression in all patients. All type shampoo and balm for dry scalp were included in the treatment regimen of all patients, while no other topical preparations were used on the scalp. Results. We observed good therapeutic and cosmetic effect in all patients, who encountered noside effects during the use of ASD-containing liposomal cosmetics. Conclusion. Combined scalp skin care with the use of modern domestic ASD-containing cosmetics will help doctor and patient to achieve the optimal result in treatment of psoriasis with scalp involvement, effectively eliminating main symptoms of the disease in a shorter time, improving patients' quality of life and giving them opportunity to lead normal life and feel comfortable in society.

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Clinical case of a very rare form of keratodermia in a child

Year: 2018, volume 14 Issue: №4 Pages: 763-765
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Morrison A.V., Marchenko V.M., Moiseev A.A., Ulanova A.M., Dobdina A.Yu.
Organization: Saratov State Medical University
Summary:

 Cases of keratoderma are the most common among genodermatoses and take the second place after a group of ichthyosis. The frequency of occurrence of keratodermia in the world, including Russia, is from 1:300 to 1:15000. There is a very rare form of diffuse keratoderma: Olmsted Syndrome, which in 2009 is described in 10 sources of scientific literature. The defeat not only affects the palms and soles, and skin around the orifices, forms a flexion deformity and con-tracture fingers, until spontaneous amputation. Some observations noted the presence of follicular keratosis of the extremities, leukokeratosis on the face and language, pererastayut joints, alopecia, absence of premolars. We present a clinical case of a patient with this pathology.

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Neurofibromatosis in the practice of dermatology

Year: 2018, volume 14 Issue: №4 Pages: 760-763
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Morrison A.V., Marchenko V.M., Moiseev A.A., Sherstobitova K.Yu., Ishmukhametova R.A.
Organization: Saratov State Medical University
Summary:

Neurofibromatosis belongs to the group of systemic hereditary diseases from the group of phakomatosis, characterized by developmental defects of ectodermal and mesodermal structures, mainly of the skin, nervous and bone systems, with an increased risk of developing malignant tumors. There are 7 types of the disease include a wide range of clinical manifestations even within the same family: a progressive course, the involvement of almost all organs and systems in the process, a high risk of complications, including many serious and fatal (cardiovascular) pulmonary insufficiency due to severe skeletal abnormalities, malignant degeneration by neurofibromas, etc.). An analysis of 5 clinical cases with neurofibromatosis is presented.

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Clinical case of the Besnier-Boeck-Shaumann syndrome in dermatology practice

Year: 2018, volume 14 Issue: №4 Pages: 755-757
Heading: Dermatovenerology Article type: Case report
Authors: Slesarenko N.A., Morrison A.V., Marchenkna E.M., Moiseev A.A., Roshchepkin V.V.
Organization: Saratov State Medical University
Summary:

Sarcoidosis (Besnier-Boeck-Schaumann syndrome) is a benign systemic disease, which is based on the defeat of the reticuloendothelial system with the formation of epithelioid cell granulomas without caseosa and perifocal inflammation in the absence of Mycobacterium tuberculosis. It occurs in all countries of the world, but the highest incidence is recorded in Northern Europe and the United States. The incidence ranges from 11 to 35 per 100,000 population. The etiology of the disease is unknown. The pathogenesis is based on delayed hyperergic immune reactions, which lead to the formation of granulomas involving T cells, as well as the release of various chemokines and cytokines, including tumor necrosis factor (TNF-alpha). The aim of the work is to present a clinical case, due to the rarity of dermatosis, as well as the complexity of diagnosis.

Keywords: rare dermatoses
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Psoriasis onset risk assessment in persons with hereditary predisposition with age, stress level and eating behavior taken into account

Year: 2018, volume 14 Issue: №4 Pages: 751-754
Heading: Dermatovenerology Article type: Original article
Authors: Shnaider D.A.
Organization: Saratov State Medical University
Summary:

Purpose: to analyze the significance of stress levels and psychology of eating behavior in people with hereditary predisposition for psoriasis for assessment of psoriasis manifestation risk in the next three years. Material and Methods. Two hundred eighty seven people aged 21-63 years with newly diagnosed psoriasis were investigated. All patients were surveyed using Holmes — Rahe Stress Inventory to assess their stress levels and Dutch Eating Behavior Questionnaire to determine the type of their eating behavior. Results. It has been established that external and emotional eating behavior in people with hereditary predisposition to psoriasis is an unfavorable prognostic factor for manifestation of dermatosis at an earlier age. Conclusion. In persons with hereditary burden index over 0.6 units psoriasis can manifest with stress level below 150 points, as determined by Holmes — Rahe questionnaire, while in persons with a hereditary burden index below 0.2 units disease manifestation is largely associated with a stress level over 300 points.

The effect of medical and social factors on compliance to prevention recommendations in psoriasis patients

Year: 2018, volume 14 Issue: №4 Pages: 748-751
Heading: Dermatovenerology Article type: Original article
Authors: Shnaider D.A., Bakulev A.L.
Organization: Saratov State Medical University
Summary:

Purpose: to evaluate the effect of medical and social factors on compliance to recommendations for prevention of psoriasis in affected patients. Material and Methods. Two hundred eighteen patients aged 22-43 years with 1 to 10 years from the onset of psoriasis were observed for one year. Patients were surveyed to evaluate their willingness to follow the recommendations for prevention of disease exacerbations after a detailed explanation of these preventive measures. Results. It has been established that men living in rural areas, having a family and with more than 5 years since the onset of psoriasis belong to a social group which has a tendency to ignore most recommendations for prevention of psoriasis. Conclusion. A regression analysis has demonstrated a relationship between degree of compliance to doctor's recommendations for prevention of exacerbations and their annual frequency.

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