№2, 2012, volume 8

Studying of dynamics and role of neurologic disorders in an assessment of surgical treatment effciency of nonspe-cifc purulent diseases of a backbone was the goal of the research. As a material of research two groups of patients, check group — 73 patients, the main group — 110 patients, were treated with nonspecifc purulent diseases of a backbone served. After surgical treatment essential regression of initial neurologic disorders was observed. Considerable changes of a pain vertebrogenic syndrome and neurologic defciency are sensitive criteria of an assessment of effcien-cy of results of the surgical treatment, as it refects accurate dynamics of initial indicators by the end of hospitalization.

The goal of the research is to analyze the dynamics of the clinical picture at multiple sclerosis (MS) patients living in Rostov region, who got the disease over the 1965 to 2010 period. The clinical data of 505 MS patients have been analyzed (age, gender, MS onset peculiarities, speed of MS progression, the time of reaching 3,4 and 6 EDSS scores). Worsening of the natural MS course over recent decades in population of Rostov region has been identifed. Taking into account the multifactor nature of multiple sclerosis, the fact of worsening can be explained by the increase of negative environmental infuence, which should be considered while medico-prophylactic organizations.

Analysis of alcohol and dyscirculatory encephalopathies among the elderly and working age. Material and methods. A survey of 781 patients of neurological departments of a hospital of the Central Clinic № 58 of the Federal Medical-Biological Agency and the City Hospital № 2 Severodvinsk in Arkhangelsk region in 2004 – 2010. During the research specifc information about the prevalence of alcohol and discirculatory encephalopathies among different age and gender and social groups have been revealed. The annual increase in the number of patients with alcohol encephalopathy is accompanied by the growing number of elderly patients. In a signifcant percentage of the organization of treatment include intensive care due to the rapid development and severe disease on the background of comorbid somatic pathology is needed.

Immunograms of 50 healthy people and 117 neurooncologic patients were analysed as comparison of their status of health and pathology in their immunity. Differences in immune parameters in test groups interpreted as reorganization of immune homeostasis with functional immunodefciency were determined by mathematic methods.

The article presents data on risk factors that contribute to the development of suicidal behavior. The development of suicidal behavior is infuenced by a number of factors. These include — gender, age, residence, occupation, marital status, health status, etc. A number of studies indicated the impact of economic and social factors on the level of suicidal activity of the population. Observed relationship between mental disorders, substance abuse (particularly alcohol) and suicide. In this case, the presence of numerous investigations in the feld of Suicidology, a number of problems still remains unsolved. Further study of issues relating to risk factors that infuence the development of suicidal behavior. Of particular note is the importance of “regional” risk factors that most infuence on the formation of suicidal behavior in a particular region.

Purpose: to study the dental status and neurological symptoms in patients with fractures of the mandible for improving diagnosis, predicting the course of reparative processes and the application of preventive measures of infam-matory complications. Material. We observed 132 patients with mandibular fractures of different location, the hospital received no later than 3 days after injury and comparison group, consisting of 15 healthy people. Dental status of patients included clinical examination: identifying reasons for injuries, complaints external examination of maxillofacial area. Assessment of pain that was observed in patients in the area of innervation of the trigeminal nerve, was carried out using a scale for measuring the intensity of pain and need for analgesics (Lantsev EA, AA Smirnov, 1990). Zone of hypesthesia and hyperesthesia were detected in patients in the study of the surface (pain, temperature and tactile) and the deep sensitivity of the skin. State of the motor portion of the third branch of the trigeminal nerve was assessed by palpation of masticatory and temporal muscles, according to electromyographic, in the late periods of the presence of atrophy of the masticatory muscles on the affected side and disturbance trajectory of the mandible. In addition, elec-trophysiological examination included registration of trigeminal somatosensory evoked potentials. The study of pain sensitivity of the teeth was carried out using a digital tester to determine the viability of the pulp «Digitest». This study was conducted on the day of admission and on the 10th day of treatment. Results. Clinical and instrumental evaluation of patients with uncomplicated fractures of the mandibular nerve fber damage detected in 100 % of cases. In complicated fractures clinically identifed sensory disorders paresteticheskih signs of interest in the trigeminal nerve were found in 51.8 % of cases. In patients with no sensory disorders paresteticheskih using electrophysiological methods trigeminal interest in fractures of the lower jaw found in 26.9 % of all cases. Thus, the overall damage to the trigeminal nerve in complicated fractures of the mandible comprise 77.8 % of cases. Conclusion. The results of our study, often leaving by the wayside, neurological symptoms affect the course and the healing of fractures of the mandible. Sensory disturbances in the form paresteticheskie hyperesthesia after the therapy offset, or pass into a more pronounced form — gipesteticheskie violation. Uncomplicated fractures of the lower jaw, accompanied by gipesteticheskimi sensory symptoms, in most cases are complicated. In our study, sensory disorders paresteticheskie in complicated fractures were found — in 77.8 % of patients. Undoubted interest of the trigeminal nerve in the development of complications of fractures, which was confrmed in our work. Thus, this study will enable the practitioner without additional methods reliably suggest a possible neurological symptoms, the recovery rate of trigeminal nerve and to adjust therapy in patients with mandibular fractures.

The goal of the research is to study features of the clinico-physiological prediction of nonspondilogical dorsopathy in young adults with psycho-social dysadaptation syndrome. 105 young adult patients with nonspondilogical dorsopa-thy and psycho-social disadaptation syndrome were examined. The received results revealed that psycho-social and biomechanical factors infuence as the chronisation of pain syndrome as progression of functional and organic changes in locomotive sphere. Using the anamnestic, physiological, neurological, and experimental psychological approach the received research fndings have promoted methods of approaching predictive risk estimation in manifestation of neurological disorders caused by dorsopathies.

Цель: изучить клинические особенности протекания классической невралгии тройничного нерва (НТН) при различных нейроваскулярных конфликтах на основании анализа отдельных симптомов заболевания. Материал и методы. Обследовано 200 больных в возрасте от 31 до 86 лет с диагнозом НТН, у которых нейроваску-лярный конфликт был верифицирован при выполнении им микроваскулярной декомпрессии (МВД) корешка тройничного нерва. Результаты. Установлено, что в подавляющем большинстве наблюдений в конфликте с КТН принимают участие артерии мозжечка (96 %) и только в 4 % был конфликт с веной. Чем выше частота приступов, тем хуже показатели повседневной активности больного. Чем в более старшем возрасте начинается заболевание, тем короче его продолжительность. Большей продолжительности заболевания соответствуют большая продолжительность последнего обострения и большая частота приступов. Большей частоте приступов соответствует меньшая продолжительность приступа.

The goal of the research is studying of patients who suffer from disequilibrium because of the gerontal dyscir-culatory encephalopathy (DE) with borderline disorders. The research also highlights possible relationship between depression and postural abnormalities using stabilometrics. 72 patients of 75 – 90 years old with dyscirculatory en-cephalopathy were examined. There were clinical and psychometric trials. Mental depression was detected according to depressive disorder criteria of ICD-10 (International Classifcation of Deseases-10^th revision). Clinical assessment of static sense according to R. Bohannon scale (1989). Stabilometrics was carried out in compliance with European open eyes — methodology using “MBN — Biomechanics” complex (Moscow).During the tests two groups of patients were sorted out. They are the main group consisted of 56 patients with depressive symptom and a group for comparison consisted of 16 patients without anxiety or depression. The groups are comparable to age and cognitive defect rate. There was no difference according to clinical assessment of static sense according to R. Bohannon scale. The length and the area of a stabilogram, the centre of pressure movement speed in the main group is higher because the oscillation amplitude in the medium frequency area in frontal plane.The research concluded that depression intensifes balance disorder at patients with gerontal dyscirculatory en-cephalopathy. This disorder can be revealed by computer stabilometrics method. These disorders are the consequences of the infuence of phrenopathy on muscle tone.

The paper presents literature data on the polymorphism of mental disorders in perimenopausal period in women and the theories of the climacteric syndrome. According to current hypothesis, melatonin has antigonadotropnym properties. The sharp decline in melatonin levels in the body during puberty promotes activation of pituitary gonadotrophic function, the development of the follicle stimulating hormone and luteinizing hormone, which have a stimulating effect on the sex glands. Involvement of melatonin in the pathogenesis of climacteric syndrome has been insuffciently studied, and studies devoted to the use of melatonin as a therapeutic agent are contradictory. Further study of the role of melatonin in the occurrence of the climacteric syndrome will understand the possibilities of pharmacotherapy considered disorders.