Saratov JOURNAL of Medical and Scientific Research
Home

Microbiological aspects of acute odontogenic osteomyelitis in children

Year: 2023, volume 19 Issue: №2 Pages: 145-148
Heading: Stomatology Article type: Original article
Authors: Halyuta Е.Е., Mokhnacheva S.B., Dugina I.G., Kutarenko A.D., Fomina A.A.
Organization: Izhevsk State Medical Academy, Headofthe Department of Clinical Diagnostic Laboratory №2 of the Respublican Children's Clinical Hospital, Izhevsk, Russia
Summary:

Objective: to determine the species composition of pathogens of acute odontogenic inflammatory processes of the jaws in children, to determine the sensitivity and resistance of the isolated microflora to antibiotics of various groups, as well as to determine the dependence of the characteristics of the clinical course of the disease on the type of dominant pathogen. Material and methods. The analysis of the results of microbiological methods for the study of exudate from purulent odontogenic foci of 900 children, due to periostitis and osteomyelitis of the jaws, was carried out. Results. In 65.6% of cases, the causative agent was Pyogenic streptococcus or group A beta-hemolytic streptococcus (BHSA) ith a high level of sensitivity to vancomycin (99%), fluoroquinolones (98%), beta-lactams (91 %) and the highest percentage of resistance to macrolides (41%). Streptococcus viridans (6.1%), Streptococcus pneumoniae (4.3%) and others were also isolated; mixed microflora (14.3%). The syndrome of endogenous intoxication of the body was manifested in 56% of cases by fever, in 38% by leukocytosis, in 57.4% by accelerated ESR. There was no statistically significant difference in the degree of endogenous intoxication in groups with different types of streptococcus. Conclusions. The cause of the inflammatory process of the jaws in 65.6% of cases was BHSA with a high level of sensitivity to vancomycin (99%), fluoroquinolones (98%), beta-lactams (91 %).

Keywords: sensitivity and resistance to antibiotics, osteomyelitis, childhood, acute odontogenic periostitis

Bibliography:
1. Drobyshev AYu, Yanushevich 00. Maxillofacial surgery. Moscow: GEOTAR-Media, 2018; 880 p.
2. Bazikyan ЕА, Chunikhin АА. Odontogenic inflammatory diseases — just about the complex. Moscow: GEOTAR-Media, 2017; 160 p.
3. Stolbov IYu, Kuznetsova NL. Complex treatment of patients with chronic osteomyelitis of the lower jaw. Problemy Stomatologii. 2010; (4): 54-5.
4. Supiev ТК, Negametzyanov NG, Nurmaganov SB. Prevention and treatment of odontogenic inflammatory diseases in children in the Republic of Kazakhstan. Stomatologiya Detsk-ogo Vozrasta i Profilaktika. 2017; 16 (4): 53-6.
5. Fantoni М, Taccari F, Giovannenze F. Systemic antibiotic treatment of chronic osteomyelitis in adults. Eur Rev Med Pharmacol Sci. 2019; 23 (2 Suppl): 258-70. DOI: 10.26355/eur-rev_201904_17500.
6. Badikov VD. Microbiological bases of antimicrobial therapy of infectious diseases: A guide for physicians. Saint Petersburg, 2005; 184 p.
7. Privol'nev VV, Rodin AV, Karakulina EV. Local use of antibiotics in the treatment of bone infections. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya 2012; 14 (2): 118-31.
8. Minaev SV, Filip'eva NV, Leskin VV, et al. Microbiological spectrum of pyoinflammatory diseases causative agents in children at a multispeciality hospital. Medical News of the North Caucasus. 2018; 13 (1): 112-4.
9. Makeeva IM, Daurova FYu, Byakova SF, et al. Sensitivity of microbial associations of periodontal pocket exudate and odontogenic focus to antibacterial drugs. Stomatologiya. 2016; 95 (3): 2630.
10. Ippolitov EV, Didenko LV, Tsarev VN. The characteristics of morphology of biofilm of periodontium under inflammatory diseases of gums (chronic catarrhal gingivitis, chronic periodontitis, Candida-associated periodontitis) according results of electronic microscopy. Russian Clinical Laboratory Diagnostics. 2015; 60 (12): 59-64.

AttachmentSize
2023_02_145-148.pdf347 KB
All articles of the authors: Mokhnacheva S.B., Kutarenko A.D., Halyuta Е.Е., Fomina A.A. , Dugina I.G.

No votes yet