Saratov JOURNAL of Medical and Scientific Research

2013, volume 9

Nutrition of low birth weight infants

Year: 2013, volume 9 Issue: №4 Pages: 720-725
Heading: Pediatrics Article type: Review
Authors: Kadymova I.I., Bochkova L.G.
Organization: Saratov State Medical University
Summary:

The article is concerned with the current state of nutrition of low birth weight infants. Anatomo-physiological features of digestive system of heterogeneous cohort of low birth weight infants are given. The article presents the description of metabolism of basic food ingredients in neonatal age. The analysis of efficiency of modern methods of enteral and parenteral nutrition of newborns with morphofunctional immaturity has been carried out. The necessity of complex programming of specific nutrition schemes for low birth weight infants of different weight categories has been proved in the work. The method of complex programming will guarantee safe survival of low birth weight infants.

Keywords: feeding, low birth weight, newborn, nutrition

Factors influencing the level of physical development of premature newborns

Year: 2013, volume 9 Issue: №4 Pages: 714-719
Heading: Pediatrics Article type: Original article
Authors: Vostrikova G.V., Ippolitova L.I., Pochatkov V.A., Popova I.N.
Organization: Voronezh Regional Children’s Hospital №1, Voronezh State Medical University n.a. N.N. Burdenko
Summary:

Purpose: to assess the factors having impact on physical development of prematurely born children at birth. Materials and Methods. 1099 case histories of newborns, the exchanged cards of pregnant women, birth case histories of women who gave birth in gestational age from 22 to 37 weeks. Results. It has been shown that there are significant indices effecting premature birth affect: chronic inflammatory diseases of the oropharynx, gastrointestinal tract, diabetes, thyroid disease, pathology of vision, infectious diseases, skin diseases; sexually transmitted infections, chronic pelvic inflammatory disease, cervical erosion, genital infantilism; preeclampsia of the first and second half of pregnancy, chronic fetoplacental insufficiency, anemia, inflammatory diseases during pregnancy, acute respiratory viral infections, obesity, gestational diabetes and pyelonephritis; prenatal pouring out of amniotic fluid, umbilical cord pathology, cho-rioamnionitis. Defined correlation between weight and height indicators of premature infants at birth and groups of medicines that women have during their pregnancy. Conclusions. Identification of factors affecting the level of physical development of premature children is important in determination of women with a higher probability of birth of children with intrauterine development and for assessing the further development of these children.

Keywords: child, physical development, prematurely-born

Application of modified auditory profile in observation of hearing rehabilitation effects among adult partially deaf patients with cochlear implant system

Year: 2013, volume 9 Issue: №4 Pages: 707-713
Heading: Otolaryngology Article type: Original article
Authors: Pankovska A., Solnitsa J., Skarzhynski Kh., Skarzynski P. Kh.
Organization: Warsaw Medical University, Warsaw Institute of Physiology and Pathology of Hearing, Kajetany World Hearing Center, Kajetany Institute of Sense Organs
Summary:

Aim: to obtain results in order to organize an individual profile of patient's hearing skills, which is a graphic illustration of obtained results that are used to monitor and provide appropriate assessment of the rehabilitation process using the modified set of hearing abilities tests. Material and methods. Material includes 24 adult patients (19 female and 5 male) with partial deafness. All of them use cochlear implants. 6 patients have been using the Cl for no more than 6 months. 12 subjects have been using the Cl for more than 6 months, 3 of them have been using the Cl for more than a year and 3 people have been using the Cl for more than 24 months. Results. Research was based on 18 tasks. In the 8 of them 24 patients obtained the result of 100% identification just one month after the first speech processor fitting. However significant changes were observed in the remaining 10 tasks. 3 complete profiles of the patients hearing skills were created. Conclusions. Results obtained by the patients confirm that the set of supervision materials designed to control the effects of rehabilitation and proposed as pilot study is valuable and can be used in diagnostics. Formula developed on the basis of auditory skill profile of the patient provides clear information on patient's progress (both to a patient and a therapist). It helps determine exercises for the next stages of rehabilitation.

Keywords: partially deaf patients, cochlear implants, auditory skill profile

Laser thermal therapy is increasingly being used in clinical practice for cancer treatment. Its major limitation is associated with low spatial selectivity. This restriction may be excluded by the use of plasmon-resonant gold nanoparticles as photothermal

Year: 2013, volume 9 Issue: №4 Pages: 700-706
Heading: Oncology Article type: Review
Authors: Chumakov D.S., Basko M.V., Dikht N.I., Bucharskaya A.B., Rodionova Т.I., Terentyuk G.S.
Organization: Saratov State Medical University, Saratov state university
Summary:

Laser thermal therapy is increasingly being used in clinical practice for cancer treatment. Its major limitation is associated with low spatial selectivity. This restriction may be excluded by the use of plasmon-resonant gold nanoparticles as photothermal sensitizers. Tunable synthesis, unique optical properties and low toxicity make gold nanostructures promising as a therapeutic agent for cancer treatment. The research work has presented the experimental data that concern the use of plasmon photothermal therapy for the treatment of transplanted and induced tumors of laboratory animals. Taking into consideration the research results it is determined that the transition of this therapeutic technology into the clinical practice can be predicted.

Keywords: gold nanoparticles, laser photothermolysis

Seasonal pattern to multiple sclerosis in newborns in Bashkortostan

Year: 2013, volume 9 Issue: №4 Pages: 697-699
Heading: Neurology Article type:
Authors: Magzhanov R.V., Sharafutdinova L.R., Bakhtiyarova K.Z.
Organization: Bashkiria State Medical University
Summary:

Research objective is to investigate the seasonal pattern to multiple sclerosis (MS) in newborns in the Republic of Bashkortostan (RB) depending on months of year in comparison with the RB population. Materials. Months of the birth of 1224 patients with MS republican have been analyzed in the center of the Republic of Bashkortostan (Ufa). The data of patients were compared to the data of birth rate in the RB within a year. Results. The majority of patients was born in May (12%), and the minimal amount of patients was determined in November (5.6%) and December (4.4%) that authentically differs from the rate of birth in various months of the year in the RB (p

Keywords: birth seasonal pattern, multiple sclerosis, vitamin D3

Personal peculiarities in patients with middle cerebral artery infarction

Year: 2013, volume 9 Issue: №4 Pages: 695-697
Heading: Neurology Article type: Original article
Authors: Antonova N.A., Sholomov I.I.
Organization: Saratov State Medical University
Summary:

The purpose of the work is to reveal personal peculiarities in patients who have suffered middle cerebral artery infarction. Material and Methods. 39 patients with middle cerebral artery infarction have been under the study. All patients have received clinical instrumental inspection (neurologic survey, duplex ultrasound investigation of vessels of neck, head and brain, the research CT or MRT). Personal peculiarities have been studied by "The standard multiple-factor method of research of the personality" (PITCHES). Results. Psychological reactions for the disease have been determined. They include hypochondria, depression, psychasthenia and anxiety. Conclusion. Personal peculiarities in patients suffered from middle cerebral artery infarction may be characterized by the appearance of psychological response to the psychotraumatic situation. Therefore it is necessary to give psychotherapeutic aid.

Keywords: cerebral infarction, middle cerebral artery, personal peculiarities

Frequency of occurrence of chronic diseases among former athletes depending on gender

Year: 2013, volume 9 Issue: №4 Pages: 691-694
Heading: Therapeutic exercise, sports medicine Article type: Original article
Authors: Fedotova I.V., Statsenko М.Е., Bakulin V.S., Sentyabrev N.N.
Organization: Volgograd State Academy of Physical Education, Volgograd State Medical University
Summary:

The aim of the article is to study the analysis of the frequency of occurrence of chronic diseases among former athletes depending on gender — specific. Material and Methods. 80 former athletes who finished sports activity no more than 5 years ago (this period is adopted for the early post-sports period) at the age of 20-35 were examined. The analysis of medical records, inspection and consulting expertise required to verify the diagnosis. Results. Statistically significantly higher level of disease is defined among former male athletes in comparison with the women who have stopped regular training and competitions. Conclusions. The determined incidence of chronic disease in former athletes might be substantiated by the absence of proper medical care to former athletes immediately after the cessation of active training and competitions.

Keywords: chronic diseases, former athletes, gender factors, post-sport period

Rehabilitation of patients with cerebral palsy using simulators

Year: 2013, volume 9 Issue: №4 Pages: 687-691
Heading: Therapeutic exercise, sports medicine Article type: Original article
Authors: Rogov A.V.
Organization: Seversk Rehabilitation Center for Challenged Children and Teenagers
Summary:

The Objective is to develop new simulators available that increase the effectiveness in therapy in patients with cerebral palsy. The inspection and rehabilitation of 70 patients with Children Cerebral Paralysis in spastic form have been carried out. Objects and methods. In basic group (35 children) complex treatment has been improved by the trainings with help of authors. Results. The results of therapy by such categories as contact, movement, self-service, playing activity have been more evident in the group where training complexes have been used. Conclusion. It has been proved that therapeutic and rehabilitation strategies for disabled children should be developed.

Keywords: cerebral palsy, children's disability, orthopedic pathology, rehabilitation

Optimization technique of the stay of person in the middle-altitude conditions

Year: 2013, volume 9 Issue: №4 Pages: 684-686
Heading: Therapeutic exercise, sports medicine Article type: Original article
Authors: Borisenko О.V., Khramov V.V., Shpitalnaya V.P., Tolstokorov S.A.
Organization: Saratov State Medical University
Summary:

The objective: In order to improve exercise capacity in the middle-altitude conditions a technique of urgent adaptation with use of the compact device has been developed. Material and Methods. The study included two groups of people involved in mountain tourism, on the move and stay in the midlands, which used (experimental group) and didn't use (control group) the developed technique. Considering the specificity of observations directly on the mountain route, the compact equipment and functional studies (pulse oximetry, spirometry, peak flow, the dynamic measurement of pulse and blood pressure with the calculation of double product index) were used to monitor the experiment. Results. During the experiment changes of the data characterizing positive development of the functioning of human cardiore-spiratory system during the physical activities in the conditions of middle mountains were recorded (peak expiratory flow rate (from 512,86 to 592,86 I / min, t = 2,25, or by 115,6% in the experimental group) and double product index (from 95,66 to 127,09 units., t = 2,41, or by 132,9% in the experimental group). Conclusion. Thus, the offered device and its technique compose an effective scheme of preliminary preparation of cardiorespiratory system to stay in the middle-altitude condition and can be recommended for use in need short-term adaptation.

Keywords: training, physical activity, middle altitude, hypoxia

Markers of systemic inflammatory response in coxarthrosis

Year: 2013, volume 9 Issue: №4 Pages: 679-683
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: Korshunov G.V., Shakhmartova S.G., Puchinyan D.M.
Organization:
Summary:

Objective: to detect markers of the systemic inflammatory response syndrome in patients with coxarthrosis by means of assessment of the status of the hemostasis system, endothelium function and inflammation intensity. Material and Methods. The indices of the plasmatic hemostasis, levels of VCAM-1, ICAM-1, ELAM-1, VEGF-A, neop-terin were analyzed. Results. It has been found that among the patients with hip coxarthrosis a group of patients (47%) with endothelium dysfunction, cellular immunity activation, a high content of Soluble Fibrin Monomer Complex and D-dimers and a group of patients (53%) without any abnormalities in these parameters should be differentiated. Conclusion. Among the patients with hip coxarthrosis a group with signs of a systemic inflammatory response syndrome (occurrence of endothelium dysfunction, cellular immunity activation, a high content of Soluble Fibrin Monomer Complex and D-dimers) and a group of patients with reference values of these parameters can be determined. The markers of the systemic inflammatory response syndrome in cases with hip osteoarthrosis are Soluble Fibrin Monomer Complex and D-dimers, high levels of intercellular adhesion molecule-1 (slCAM-1), vascular cell adhesion molecule-2 (sVCAM-1), cell adhesion E-selectin-1 (ELAM-1) and Neopterin (Np).

Keywords: cellular immunity, coxarthrosis, hemocoagulation, markers of systemic inflammatory response syndrome