Saratov JOURNAL of Medical and Scientific Research

2011, volume 7

Complex experimental investigation of antibacterial silver microimplants and technology of their production

Year: 2011, volume 7 Issue: №1 Pages: 127-132
Heading: Stomatology Article type: Original article
Authors: Suyetenkov D.Ye., Lyasnikova A.M, Taran V.M., Gnetnev A.M., Firsova I.V.
Organization: Saratov State Technical University, Saratov State Medical University
Summary:

Modification technology of surface of orthodontic microimplants is developed with the help of adding Poviargolum liquid into the structure of plasma evaporated hydroxyapatite coating in the process of finishing ultrasonic treatment. It is shown by experiments, that silver coatings inhibit biochemical activity of staphylococcus and its hemolytic properties

Keywords: silver coatings, orthodontic microimplants, nanostructuring, antibacterial properties

Development and clinical course of diseases accompanied by connective tissue dysplasia in children of puberty age

Year: 2011, volume 7 Issue: №1 Pages: 123-126
Heading: Pediatrics Article type: Original article
Authors: Sidorovich O.V., Goremykin V.I., Elizarova S.Yu., Korolyova I.V.
Organization: Saratov State Medical University
Summary:

The risk of development and clinical course of somatic diseases have been analyzed in the research work. 111 adolescents suffering from connective tissue dysplasia have been under the study. It has been stated that the frequency of somatic diseases among adolescents with connective tissue dysplasia is higher than this frequency among adolescents without such disease. Phenotypic signs of connective tissue dysplasia have been revealed. They are responsible for the development of bronchial asthma and severe stomach ulcer

Keywords: somatic diseases, puberty period, connective tissue dysplasia

Peculiarities of cardiac hemodynamics and functional state of left ventricular myocardium in teenagers with connective heart tissue dysplasia

Year: 2011, volume 7 Issue: №1 Pages: 119-123
Heading: Pediatrics Article type: Original article
Authors: Makhmudova F.M.
Organization: Azerbaijan Medical University
Summary:

The aim of investigation is to study heart hemodynamics in teenagers with connective tissue dysplasia of heart (CTDH). 35 patients ages 12 to 15 years with CTDH have been observed: Group I (n=14) are the patients with mitral valve prolapse (MVP) without mitral regurgitation (MR) and myxomatous degeneration(MD) or isolated minor heart abnormalities (MHA), Group II (n=11)are patients with MVP and MR in combination with 1 or2 MHA, and Group III (n=10) are patients with MVP and mixoid degeneration (MD) in combination with 2 or more MHA. The control group consisted of 15 patients of the same age without MHA. All the children passed Doppler and echocardiography. According to the results significant changes of cardiohemodynamic indices in patients of Group I were not observed. The changes of size and volume indices of the left ventricle (LV), increase in wall thickness and diastolic dysfunction of the LV were observed in Group II. The significant changes of systolic function of left ventricular myocardium were observed in Group III. The study comes to the conclusion that teenagers with CTDH have definite changes of heart hemodynamics and functional state of left ventricular myocardium. These changes depend on mitral regurgitation, myxomatous degeneration and MHA combination

Keywords: systolic and diastolic dysfunction, myxomatous degeneration, mitral regurgitation, minor heart abnormalities, connective tissue dysplasia

Retrospective analysis of follow-up results in patients with skin lymphomas of low degree malignancy

Year: 2011, volume 7 Issue: №1 Pages: 115-118
Heading: Oncology Article type: Original article
Authors: Tarasov V.V.
Organization: Saratov Military Medical Institute
Summary:

Administration of specific chemotherapy (cytostatics) has great significance in the treatment of skin lymphomas of low degree malignancy. The research goal is to study follow-up results of cytostatic therapy of skin lymphomas. Retrospective observation of survival of patients with T-cell epidermothropic skin lymphomas using special therapy and without its use has been studied. Comparative analysis of survival rate in two groups of patients has been done. 40 patients received cytostatics and 32 patents were not treated by chemotherapy. The first group of patients showed the reduction of survival level and increase of mortality level from skin lymphomas of low degree malignancy. The research findings proved the influence of cytostatic therapy on the survival of patients with skin lymphomas of low degree malignancy

Keywords: survival analysis, skin lymphoma, cytostatics

Advanced methods of treatment of hypophysis adenoma

Year: 2011, volume 7 Issue: №1 Pages: 112-114
Heading: Neurology Article type: Review
Authors: Zhestikova M.G., Kan Ya.A., Sholomov I.I.
Organization: Saratov State Medical University, Novokuznetsk State Medical Institute for Advanced Training of Physicians, Novokuznetsk State Clinical Hospital № 1
Summary:

Hypophysis adenomas are mostly spread in the chiasmatic cellular area. They account 18% of all new brain formations, the structure of pituitary adenomas includes prolactinomas in a large number of cases which are manifested by the syndrome of hyperprolactinemia and hormone inactive hypophysis tumours (35%). Somatotropins (13-15%) are lower in frequency, the main clinical feature is acromegalia. One can rarely reveal corticotropins (8-10%), gonadotro-pins (7-9%) and thyrotropins (1%) and their mixed forms. Transsphenoidal surgical interventions are considered to be methods of choice treatment of hypophysis adenomas and other formations in the chiasmatic cellular area. Alternative methods of treatment are conservative. They can be as an addition to microsurgery (radiotherapy)

Keywords: neurosurgery, medication, hypophysis adenoma

Exrtraarticular manifestations of psoriatic arthritis in patients with low clinical and laboratory activity of disease

Year: 2011, volume 7 Issue: №1 Pages: 107-111
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: Gaidukova I.Z., Kargalskaya O.G., Rebrov A.P.
Organization: Saratov State Medical University
Summary:

The research goal is to present the clinical observation that shows possibility of combination of low clinical and laboratory activity of psoriatic arthritis with 1) a large amount of exrtaarticular manifestations; 2) severe lesion of internal organs; 3) development of nephritis and hepatitis; 4) cardiovascular system pathology. The possibilities of different diagnostic and therapeutic methods have been considered in the article

Keywords: psoriatic arthritis, nephritis, extraarticular manifestations, arterial stiffness

Peculiarities of infectious diseases course accompanied by quinsy syndrome in children (data from children infectious hospital)

Year: 2011, volume 7 Issue: №1 Pages: 103-106
Heading: Infectious Diseases Article type: Original article
Authors: Borisova O.V., Gasilina E.S., Santalova G.V., Mitrofanov AM, Ovchinnikova T.A.
Organization: Samara State Medical University
Summary:

The research goal is to study morbidity dynamics for the period of 15 years and to determine clinical signs that accompany quinsy syndrome (diphtheria, infectious mononucleosis, scarlet fever, quinsy). Retrospective study analysis of annual reports and case-histories was carried out. 323 cases of infectious diseases accompanied by quinsy syndrome were examined. Clinical and epidemic signs of diseases were determined during the period of morbidity raise. The current clinical course of diseases was characterized in detail. The significant percentage of renal complications in case of pharyngonasal cavity lesion was shown

Keywords: renal lesion, quinsy syndrome, morbidity dynamics, clinical signs of disease

Study of bioelectric brain activity and characteristics of heart activity in nystagmus suppressing by periodic light action

Year: 2011, volume 7 Issue: №1 Pages: 097-102
Heading: Ophtalmology Article type: Original article
Authors: Usanova Т.В., Nikolenko V.N., Skripal A.V.
Organization: Saratov National Research University n.a. N. G. Chernyshevsky, Saratov State Medical University, First Moscow State Medical University n.a. I.M. Sechenov
Summary:

Results of research of bioelectric brain activity and heart rate activity of patients with eye nystagmus with simultaneous registration of nystagmograms, electroencephalograms and electrocardiograms are given. It is shown that at periodic influence of light on the eyes of patients the interconnected reduction of amplitudes of spectral components of electrocardiograms and electrocardiograms power spectra are observed

Keywords: ophthalmology, nystagmus, frequency analysis, electroencephalography, electrocardiography

Cardiovascular mortality: quality diagnostics analysis and causal statistics of lethal outcomes

Year: 2011, volume 7 Issue: №1 Pages: 091-096
Heading: Internal Diseases Article type: Original article
Authors: Nikulina N.N.
Organization: Ryazan State Medical University n.a. I.L.Pavlov
Summary:

The high cardiovascular mortality (CVM) proves the necessity of verification analysis of cardiovascular death causes. The research goal is to determine the quality, facilities and peculiarities of cardiovascular diseases (CVD) of postmortem diagnostics and statistical recording as a cause of death. 1972 successive cases of CVM in Voronezh, Ryazan and Khanty-Mansiysk have been analyzed. The majority of deaths caused by CVD were classified as fatalities occurring outside hospital and in the absence of medical care (88.0%). Incidence of cardiovascular deaths was confirmed by autopsy in 28.3% cases. With increasing age, the incidence of detecting CVD as a cause of death increased, while the frequency of referral to autopsy consistently decreased. Chronic Ischemic Heart Disease (IHD) forms comprising 48.3% of all CVM were confirmed by autopsy results only in 29.5% of cases. Acute IHD forms (including myocardial infarction) accounted for only 11.6% of CVM; however this diagnosis was based on autopsy results in 72.4% of cases. The high death rate outside hospital and in the absence of medical care with the rare referral to autopsy, especially for elderly having chronic CVD, does not provide reliable statistical information on CVM

Keywords: cause of death, cardiovascular mortality, autopsy

Features of clinical course and quality of life in patients with chronic pancreatitis and diabetes mellitus

Year: 2011, volume 7 Issue: №1 Pages: 087-091
Heading: Internal Diseases Article type: Original article
Authors: Kunitsyna М.А., Kashkina E.I.
Organization: Saratov State Medical University
Summary:

Clinical and life quality features of 183 patients with chronic pancreatitis and diabetes mellitus were studied. We have found that the incidence of exacerbations increased by 36,7% after the appearance of diabetes mellitus, the number of days of loss of ability to work increased by 27,8%, the quality of life decreased

Keywords: diabetes, clinical course features, chronic pancreatitis