2008, volume 4

Influence ofantineoplastic drug doxorubicin and amikacin, the aminoglycoside family on adhesive activity of Escherichia coli was studied. Antimicrobialactivity(minimum inhibitory concentration-MIC) ofboth drugs against experimental strains using serial two-fold dilution method was determined. Susceptibility of E.coli to amikacin in the presence of Sand j MIC doxorubicin was studied. After 10 passages in beef-extract broth with constant and increasing doxorubicin concentrations in the presence of Sand j MIC doxorubicin, the adhesive activity of initial and passage variants according to theirability to absorb human erythrocytes 1(0) Rh+ was determined. Itwas observed that experimental strains were susceptible to amikacin (MIC 1,5-6,2 mkg/ml) butwere resistantto doxorubicin (MIC 1000 mkg/ml). Subinhibitory concentrations of this cytostatic (S and j MIC) raised the sensitivity of experimental strains to amikacin and differently effected on adhesive activity of passage variants of E.coli.

The purpose of our study is to determine morphologic changes in microvascular bed of liver in 78 female and male white rats adults on the first, seventh, fourteenth, twenty-eighth days and third, sixth, ninth months after operation. The hepatic microcirculation was analyzed using light and scanning electron microscopy, histological methods, morphometry and statistics. The splenectomy influenses on microvascular bed and hepatocytes in early periods. Itcauses irreversible morphological changes of hepatic tissue in long-term periods after operation.

By means ofhistological, immunohistochemical and cytogenetic methods of research the morphological changes of endomethum and fetoplacental tissues, obtained by the endometrectomy of the women due to spontaneous abortions of different etiology, have been investigated in this study.

On the basis of epidemiological and demographic data, hygienic indicators of the quality of drinking water and computer software STATISTICA 6.0 an intestinal infections database was developed. The effectiveness of its usage for social and hygienic monitoring and epidemiological inspection of intestinal infections was proved.

Russia’s joint to "Bologna process" sets definition of main points in innovative and integrative processes as an object for academic community. The aim of all applied innovations is to improve education quality and deep integration to European educational space. Modular principle of teaching at profile chair of pediatric faculty, presented in the article, permits to raise students' motivation in educational process; to improve formation of final-year students' professional competence by means of optimization class workand self-study.

Stomatological faculty of SaratovState Medical University was founded in 1988. During 20 years scientific stomatologic school on the basis of all major directions was formed in our university. Greatamountof high professional scientific staff and practitioners was trained.

The article gives brief biographic information about professor P.S. Grigoriev, that highlights several aspects of his becoming a scientist and founder ofSaratovscientific schoolofdermatovenereology in the first halfofthe 20th century. The scientific inputofP.S. Grigoriev in the development of native and world-wide dermatovenereological science is also shown.

In article is given the review of a modern condition of a problem of the Reino phenomenon, its diagnostic and differential diagnostics meaning. 40 afflicted persons by a systemic scleroderma and systemic lupus erythematosus with clinically apparent Reino symptoms and - 40 practically healthy internship doctors as a control group were investigated. The given research has allowed to specify features of statement of со Id test and interpret its results, to reveal pathogenetic mechanisms of infringement of a hemodynamics, including early stages of development, and to develop the most rational approaches for treatment.

We studied the use ofnon-steroid anti-inflammatorydrugs (NSAID) at the in-patient department ofcentral district hospitalwith the application ofDDD-techniques before and after the formular system adoption. After introduction of drug formular and treatment standards the use of NSAID was reduced; the physicians began to use modern drugs. Non-indicated and contraindicated NSAID were prescribed more seldom. Itwas determined that reduction of antihypertensive drugs efficiency in hypertensive patients was the main side effect of NSAID use. NSAID gastropathy occurred more seldom, and mainly in the patients receiving several NSAIDs simultaneously.

Low-intensify electro-magnetic waves (EMW) influence were studied at experiment. Certain EMI frequency regimes (they are transparent for the water and water-binding substances, and they are known as trans-resonance) can intensify the metabolic rate. In turn, certain EMW frequency regimes (they are not transparent for the water and the water-containing tissues, and they are called as non-resonance) can disturb the native electro-magnetic status of the cells and can lead to morphological changes in organs. Morphological changes in adrenal glands and cortizol level of 60 White Vistar rats (males) in serum under transparent EMW frequency regimes and non-transparent ones were examined. Transparent and non-transparent frequency regimes impact the various changes in adrenals. Cortizol level corresponds to morphologic conclusion. Stress modified EMW-effects in both variants - under resonance and non-resonance EMW frequency regimes in adrenal morphology and cortizol level.