Саратовский научно-медицинский ЖУРНАЛ

Лучевые методы оценки функции почек у детей

Год: 2018, том 14 Номер: №3 Страницы: 385-388
Рубрика: Лучевая диагностика Тип статьи: Обзор
Авторы: Чехонацкая М.Л., Аверьянов А.П., Утц И. А., Великанова М.Г., Бобылев Д. А., Чехонацкий И. А.
Организация: ФГБОУ ДПО РМАНПО Минздрава России, ФГБОУ ВО Саратовский ГМУ им. В.И. Разумовского Минздрава России, Клиническая больница имени С. Р. Миротворцева СГМУ
Резюме:

Точная оценка почечной функции имеет решающее значение для адекватного дозирования медикаментов. Наиболее информативным маркером, отражающим функциональное состояние почек, является скорость клу-бочковой фильтрации (СКФ). Определение клиренса инулина — наиболее точный способ оценки СКФ у детей и взрослых. Вместе с тем метод является инвазивным, громоздким, детям младшего возраста требуется установка мочевого катетера. Методики радиоизотопной оценки СКФ могут решить эту проблему, однако все широко используемые радиоизотопы имеют способность к незначительному связыванию с белками плазмы, что приводит к занижению реальных значений

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