Saratov JOURNAL of Medical and Scientific Research

Clinical and neurological features in patients with venous cerebral dysfunction

Year: 2019, volume 15 Issue: №2 Pages: 241-245
Heading: Neurology Article type: Original article
Authors: Gafurov B.G., Nazarova Zh.A.
Organization: Tashkent Institute of Postgraduate Medical Education,

Objective: to study the clinical and neurological features in patients with chronic cerebral ischemia, depending on the presence of venous cerebral dysfunction. Material and Methods. 168 patients sufering from chronic cerebral ischemia took part in the study (mean age 61.2±3.8 yrs; 45.2 % — men). The control group comprised 20 healthy subjects comparable in age and sex distribution. All patients with chronic cerebral ischemia underwent rheoencephalographya for detection of cerebral venous dysfunction, as well as standard clinical and neurological examination (patient»s complaints, past history, neurological status assessment). Clinical features of headache were evaluated using the original questionnaire. The intensity of headache were determined using a ten-point visual-analog scale. Cognitive function was assessed in all study groups by means of evoked potential method with using P300 technique. Results. In patients with chronic cerebral ischemia in 46.4 % of cases revealed venous cerebral symptoms. In such patients, headache syndrome is most pronounced, both by clinical criteria and by visual-analog scale score: 6.8 points against 5.1 points in patients with chronic cerebral ischemia without venous cerebral dysfunction (p<0.05). In patients with chronic cerebral ischemia with concomitant cerebral palsy revealed more pronounced comorbid background and cognitive defcits, manifested in violation of sensory integration, diferentiation of stimuli, memory and decision-making as compared with patients with chronic cerebral ischemia without venous cerebral dysfunction and healthy subjects. Conclusion. Venous cerebral dysfunction aggravated the course of chronic brain ischemia predominantly due to the presence of cognitive defciency.

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