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Features of echocardiography parameters in acute coronary syndrome combined with post-COVID syndrome

Year: 2025, volume 21 Issue: №1 Pages: 43-49
Heading: Cardiology Article type: Original article
Authors: Kozik V.A., Shpagina L.A., Shpagin I.S., Loktin E.M.
Organization: Novosibirsk State University
Summary:

Objective: to evaluate echocardiographic changes in patients with acute coronary syndrome (ACS) combined with post-COVID syndrome. Material and methods. The study included 118 patients, including 61 men and 57 women with ACS and a post-COVID syndrome. All patients underwent echocardiography on the first day, in addition to coronary angiography and general clinical examination methods. The comparison group consisted of 121 patients with ACS without post-COVID syndrome. Results. In the ACS and post-COVID syndrome group, statistically significant increases in blood pressure (relative risk — RR 2.327, 95% confidence interval — Cl 1.582-2.699), tachycardia (RR 2.067, 95% Cl 1.415-3.730), dyspnea (RR 2.022, 95% Cl 1.495-2.736), weakness (RR 4.077, 95% Cl 2.946-5.643), and insomnia (RR 1.893, 95% Cl 1.519-2.358); p<0,001, were recorded. In the group of patients with ACS and post-COVID syndrome, there was a statistically significant increase in the mean pulmonary artery pressure, dilation of the pulmonary artery diameter, and regurgitation on the mitral valve (p<0,001). The risk of developing left ventricular apex thrombosis (RR 1.785, 95% Cl 1.304-2.444), left ventricular aneurysms (RR 1.736, 95% Cl 1.23-2.443), hypokinesis and akinesis (RR 1.673, 95% Cl 1.275-2.196); p<0,05, was observed more often. Conclusion. Patients who have had ACS combined with post-COVID syndrome show more severe echocardiographic changes compared to patients without post-COVID syndrome.

Keywords: post-COVID syndrome, post-COVID period, new coronavirus infection, echocardiographic changes, acute coronary syndrome

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All articles of the authors: Shpagina L.A., Shpagin I.S., Loktin E.M., Kozik V.A.

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