Comparative analysis of methods for determining the activity of foci of localized scleroderma
Year: 2022, volume 18 Issue: №4 Pages: 729-734
Heading: Тhematic supplement Article type: Original article
Authors: Morrison A.V., Moiseev A.A., Epifanova A.Yu., Grebennikova I.P., Eldesbayeva Ya.S.
Organization: Saratov State Medical University
Heading: Тhematic supplement Article type: Original article
Authors: Morrison A.V., Moiseev A.A., Epifanova A.Yu., Grebennikova I.P., Eldesbayeva Ya.S.
Organization: Saratov State Medical University
Summary:
Objective: to characterize the methods for determining the activity of foci of localized scleroderma and conduct their comparative analysis. Material and methods. Using two female patients as examples, we compared three instrumental methods of determining localized scleroderma activity: radio-wave diagnostics (active radiometry or trans-resonance functional topography), ultrasound (ultrasound) of the skin and infrared thermal scanning (IR thermogra-phy), as a method for assessing the activity of the pathological process in juvenile localized scleroderma. Results. The thermal imager allows obtaining a visual display that clarifies the clinical picture of the disease from the entire studied area, however, changes on the skin may be lower than the diagnostic accuracy of the device. Ultrasound of the skin requires special training, a separate module and software for determining the speed of blood flow, which will allow an assessment of both morphological damage and functional disorders. At the same time, the speed of blood flow may not reflect metabolic processes in damaged tissues. Some places are difficult to explore. Radio-wave diagnostics, despite the long time and the presence of hard-to-reach places, give a more accurate result, which can be expressed by numerical indicators that remain stable for the duration of the inflammatory reaction, even after visual resolution. Conclusion. All three methods have the potential to determine the presence and activity of a localized scleroderma lesion in the areas of skin under study.
Bibliography:
1. Kreuter A, Krieg Т, Worm М, et al. German guidelines for the diagnosis and therapy of localized scleroderma. JDDG 2016; 14(2): 199-216.
2. Giuggioli D, Colaci M, Cocchiara E, et al. From localized scleroderma to systemic sclerosis: coexistence or possible evolution. Dermatol Res Pract. 2018; (2018): 1284687. DOI: 10.1155/2018/1284687.
3. Raupov RK, Imelbaev Al, Kostik MM. Juvenile localized scleroderma from the perspective of pediatric rheumatologist. Aspects of Diagnostics. Current Pediatrics. 2020; 19 (2): 150-61.
4. Mayorov R. Modern views on pathogenesis and therapy of restricted sclerodermy. Norwegian Journal of development of the International Science. 2019; (30): 32-5.
5. Chung L, Lin J, Furst DE, Fiorentio D. Systemic and localized scleroderma. Clinics in Dermatology. 2006; 24 (5): 374-92.
6. Bolotnaya LA, Kutasevich YF. Modern look to pathogenesis of localized scleroderma and chronic lupus erythematosus (review of literature). Dermatology and Venerology. 2014; 64 (2): 5-16.
7. Kotov АА. State of the antioxidant system and micro-circulation in patients with limited scleroderma and their correction by oxygen-ozone therapy. PhD diss. Moscow, 2005; 122 p.
8. Sorokina NV. Optimization of the complex therapy of patients with localized scleroderma. PhD diss. Krasnodar, 2018; 112 p.
9. Clinical guidelines 2020. Localized scleroderma. URL: https://www.rodv.ru/klinicheskie-rekomendacii/(7 Okt 2022)
10. Ovsyannikova OB, Ananyeva LP, Lesnyak VN, et al. Changes of activity index and total severity index in patients with systemic sclerosis and interstitial lung disease over a 5-year follow-up period. Rheumatology Science and Practice. 2016; 54 (3): 312-7.
11. Kameneva ЕА, Zaharina ОА, Babaeva АР. Serum gly-cosaminoglycanes and antibodies to them as diagnostic markers of vascular complications in patients with diabetes mellitus. Journal of Volgograd State Medical University. 2008; 2 (26): 50-3.
12. MedsgerTA, Bombardieri S, Czirjak L, et al. Assessment of disease severity and prognosis. Clin Exp Rheumatol. 2003; 21 (3 Suppl 29): S42-6.
13. Moiseev AA, Utz SR. Resonance radio wave diagnostics of localized sclerodermia: pilot study. Saratov Journal of Medical Scientific Research. 2017; 13 (3): 585-90.
14. Gromov MS, Terekhov IV, Bondar SS, et al. Technology for assessing the permeability of capillaries by means of active
radiometry. Journal of New Medical Technologies, eEdition. 2009; XVI (4): 177.
15. Terekhov IV, Solodukhin КА, Arzhnikov VV, et al. The possibility of using active microwave radiometry for assessing alveolar-capillary permeability in experiment. Regionarnoe Kro-voobrashenie i Microcirculacia. 2011; 4 (40): 83-6.
16. BlagodarovAV, Vlaskin SV, Gromov MS, et al. Computer analysis in TRF topography for the differentiation of malocclusion
and pathology in mammology and pulmonology. Journal of New Medical Technologies, eEdition. 2006; XIII (3): 140-3.
17. Terekhov IV, Petrosyan VI, Parfenyk VK, Arzhnikov VV. Diagnostics and monitoring of infiltrative processes in the thoracic cavity by the method of luminescent analysis. 2017. URL: http://aquatone.Su/d/447480/d/11 .infiltrativnyyeprotsessyv-grudnoypolosti.pdf (7 Okt 2022)
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