Saratov JOURNAL of Medical and Scientific Research

The effect of elective percutaneous coronary intervention on clinical and echocardiographic parameters of patients with heart failure with mildly reduced ejection fraction

Year: 2022, volume 18 Issue: №2 Pages: 227-233
Heading: Cardiology Article type: Original article
Authors: Kulbaisova S.A., Galin P.Yu.
Organization: Orenburg State Medical University

Objective: to assess the annual dynamics of clinical, laboratory and echocardiographic characteristics of patients with heart failure with mildly reduced ejection fraction after elective percutaneous coronary intervention. Material and methods. The study involved 101 patients (16 women and 85 men) with signs of chronic heart failure and ejection fraction 40-49%. The examination included scoring on the clinical condition assessment scale, six-minute walk test, determination of N-terminal prohormone of brain natriuretic peptide (NT-proBNP, pg/ml), transthoracic echocardiogra-phy. Mean age is 59±9 years. The distribution by functional classes of heart failure was as follows: I — 1%, II —63.4%, ill — 33.7%, IV — 2%. Results. After 12 months the number of points on the clinical condition assessment scale decreased from 3 (2; 4) to 1 (0; 1) points (p<0.001) mainly due to a decrease in dyspnea. The increase in distance in the six-minute walk test over 12 months was 85 (57; 115) meters (p<0.001). Mean NT-proBNP level in the group decreased from 370 (295; 459) to 264 (193; 343) pg/ml (p <0.001). Over the year, mean increase in the ejection fraction was 7±5% (p<0.001). Conclusion. Elective percutaneous coronary intervention has a positive effect on the annual dynamics of clinical, laboratory and echocardiographic parameters of patients with heart failure with mildly reduced ejection fraction.

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