Saratov JOURNAL of Medical and Scientific Research

Pathomorphological characteristics of the wound bed before skin autoplasty

Year: 2022, volume 18 Issue: №1 Pages: 73-77
Heading: Рathophysiology Article type: Original article
Authors: Bogdanov S.B., Melkonyan K.I., Polyakov A.V., Sotnichenko A.S., Verevkin A.A., Gilevich I.V., Aladyina V.A., Bogdanova Yu.A., Karakulev A.V., Medvedeva L.A., Porhanov V.A.
Organization: Kuban State Medical University, Research Institute — Regional Clinical Hospital No. 1 n. a. Professors. V. Ochapovsky

Objective: to conduct a comparative pathomorphological analysis of wounds of various origins requiring full-thickness skin autoplasty. Material and methods. Histomorphological comparison of the wound bottom before plastic surgery with full-layer skin autografts was performed in those groups of patients: 1 — for excision of scar tissue in elective surgery; 2 — traumatic detachment of the skin perform plastic surgery by Krasovitov; 3 —when excising granulation tissue to the fibrous layer. The object of research is biopsies of patients from three study groups. Results. The histologi-cal picture of wounds after scar removal is characterized by well-developed dense fibrous-cellular connective tissue, has signs of chronic inflammation. Unlike a cicatricial wound, acute lesions were characterized by granulation and mature dense fibrous connective tissue, with pronounced inflammatory changes, each of which had its own characteristics. Conclusion. The results of a comparative analysis revealed the features of the morphological picture of wounds depending on the type of injury. In the group of acute injuries, traumatic and burn wounds, the most pronounced tissue injuries were revealed. Given the data obtained, it should be assumed that full-thickness autodermoplasty will have the best result in the group of patients after planned excision of scar tissue.

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