Microflora of the conjunctival cavity in healthy subjects and in patients with some inflammatory diseases of the anterior eye segment in Kirov region

Objective: to study the microflora of the conjunctival cavity in adults in normality and in different inflammatory diseases of the anterior eye segment of patients in the Kirov region. Material and Methods. In the course of experimenting, two groups were identified: the first group consisted of 24 people (25 eyes) who were treated for different infectious and inflammatory pathologies of the ocular surface. The control group (the second group) consisted of 29 people (29 eyes) without infectious and inflammatory pathology of the organ of vision. The material was taken and then seeded on nutrient media. Results. The composition of the microflora in the patients was the same, but in different proportions. The exception was a patient who was seeded with a single microorganism that caused conjunctivitis, Proteus vulgaris; in two patients, the only microorganism in a concentration of more than 105 CFU/ml was Anaerococcus prevotii. In the first group, the most frequently isolated microorganisms were Candida sp., Staphylococcus aureus, Streptococcus pyo-genes, Peptostreptococcus, Propionibacterium granulosum, Klebsiella sp., Staphylococcus epidermidis, Escherichia coli. In the second group, microorganisms were more common: Candida sp., Klebsiella sp., Staphylococcus aureus, Propionibacterium granulosum. Conclusion. In general, the composition of the microflora in the patients was the same, but in different proportions, which indicates the conditional pathogenicity of the microflora of the conjunctival cavity. Most of patients have a high frequency and large concentrations of Candida sp., which can be explained by the peculiarities of the conjunctival microflora of the residents of the Kirov region and the impact of the COVID-19 pandemic.