Experience of treatment of progressive choroidal nevus by transpupillary thermotherapy
Year: 2021, volume 17 Issue: №1 Pages: 23-28
Heading: Ophtalmology Article type: Original article
Authors: Gurko T.S.
Organization: S. Fedorov Eye Microsurgery Federal State Institution
Heading: Ophtalmology Article type: Original article
Authors: Gurko T.S.
Organization: S. Fedorov Eye Microsurgery Federal State Institution
Summary:
Purpose: to assess the efficacy of transpupillary thermotherapy (TTT) in treatment of the progressive choroidal nevus. Material and Methods. Diagnosis and treatment of 29 patients (29 eyes) with progressive choroidal nevus were analyzed. The follow-up was from 4 months to 3 years. In the diagnosis of the neoplasm we paid a special attention to the ultrasound B-scanning, optical coherence tomography (ОСТ), OCT-angiography. According to the ultrasound scanning (B-scanning) data the neoplasm height varied from 0.78 to 3.64 mm (1.60 (1.40; 1.84) before treatment, the length varied from 1.30 to 14.05 mm (6.41 (5.12; 7.54). For treatment we used laser device IRIS MEDICAL IQ 810 "IRIDEX" in the LONGPULSE mode. Results. After treatment the prominence in the nevus zone was not defined in 14 cases (48.3%) according to B-scanning data. In 15 (51.7%) patients the neoplasm height and length decreased: prominence height was 1.40 (1.20; 1.50), varying from 0.7 to 3.1 mm, the length was from 1.3 to 7.5 mm (6.10 (4.69; 7.30). In 28 (96.5%) patients visual acuity has not changed. Conclusion. The treatment of progressive choroidal nevus by TTT showed its efficacy, safety and good tolerance.
Bibliography:
1. Shilds DzhA, Shilds KL. Intraocular tumors: Atlas and reference guide. Moscow: Izdatel'stvo Panfilova, 2018; 608 p.
2. Magaramov DA, Yarovoy АА, Solomin VA. Optimization of diagnosis and laser methods of treatment of chorioretinal neoplasms. Modern technologies in ophthalmology 2016; (3): 111-5.
3. Shields CL, Furuta M, Mashayekhi A, et al. Clinical spectrum of choroidal nevi based on age at presentation in 3422 consecutive eyes. Ophthalmology 2008; 115 (3): 546-52.
4. Shields CL, Shields JA, Kiratli H, et al. Risk factors for metastasis of small choroidal melanocytic lesions. Ophthalmology 1995; (102): 1351-61.
5. Singh AD, Kalyani P, Topham A. Estimating the risk of malignant transformation of a choroidal nevus. Ophthalmology 2005; (112): 1784-9.
6. Naumann GO, Hellner K, Naumann LR. Pigmented nevi of the choroid. Clinical study of secondary changes in the overlying tissue. Trans Am Acad Ophthalmol Otolaryngol 1971; (75): 110-23.
7. Zaldivar RA, Aaberg TM, Sternberg P, et al. Clinicopathologic findings in choroidal melanomas after failed transpupillarythermotherapy. American Journal of Ophthalmology 2003; 135 (5): 657-63.
8. Magaramov DA, Yarovoy AA, Loginov RA, Solomin VA. Remote results of laser treatment of choroidal hemangioma.
Modern technologies in ophthalmology 2017; (1): 176-8.
9. Shields CL, Furuta М, Berman EL, et al. Choroidal nevus transformation into melanoma: analysis of 2514 consecutive cases. Arch Ophthalmol 2009; 127 (8): 981-7.
10. Oosterhuis JA, Journee-de Korver HG, Keunen JE. Transpupillary thermotherapy: results in 50 patients with choroidal melanoma. Arch Ophthalmol 1998; 116 (2): 157-62.
11. Linnik LF, Magaramov DA. A 3-year experience of using transpupillary diodlaser thermotherapy as an independent method of treating uveal melanoma. Ophthalmosurgery 2003; (4): 17-24.
| Attachment | Size |
|---|---|
| 2021_01_023-028.pdf | 1.33 MB |
Русский
English