Saratov JOURNAL of Medical and Scientific Research

Antiphospholipid syndrome in a patient with myasthenia gravis: case report

Year: 2021, volume 17 Issue: №1 Pages: 148-151
Heading: Тhematic supplement Article type: Case report
Authors: Romanova T.V.
Organization: Samara State Medical University

Patients with myasthenia gravis have an increased risk of other autoimmune diseases compared to population without myasthenia gravis. The development of two autoimmune diseases in one patient suggests common pathogenetic mechanisms. The article presents a case report of progression of antiphospholipid syndrome in a 44-year-old woman 12 years after onset of myasthenia gravis with an early onset and a high titer of antibodies to acetylcholine receptors, without a history of thymectomy This woman had a good obstetric history. She was diagnosed with antiphospholipid syndrome on the basis of clinical manifestations in form of ischemic stroke, and detection of high levels of antibodies to beta-2-glycoprotein-1 twice with an interval of 12 weeks. In the scientific literature there are limited cases of

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