Saratov JOURNAL of Medical and Scientific Research

SD-OCTA parameters of the optic disk and peri papillary retina in older age group

Year: 2020, volume 16 Issue: №1 Pages: 265-268
Heading: Ophtalmology Article type: Original article
Authors: Safonenko A.Yu., loyleva Е.Е., Gavrilova N.A.
Organization: S. Fyodorov Eye Microsurgery Federal State Institution

The purpose of the study is to investigate the optic disk and peripapillary retina parameters using SD-OCTA in people of an older age group. Material and Methods. 31 patients (62 eyes), 12 males and 19 females, mean age 57.1 ±9.6 were examined. All patients underwent SD-OCT and SD-OCTA examination (RTVue XR, Optovue), by using protocol HD Angio Disk 4.5*4.5 mm. SD-OCT and SD-OCTA were used to measure the radial peripapillary capillaries (RPC, %) and retinal nerve fiber layer thickness (RNFL, urn), rim area, disc area, cup volume. Results. Mean value of the RNFL thickness was 109.7±11.1 urn. The lower value of the RNFL thickness was observed in "Tempo Inferior" and "Tempo Superior" segments. Rim area was 1.66±0.33 mm2, disc area 1.87±0.28 mm2. The mean value of RPC density in peripapillary retina was 52.2±2.3%. The lower value of the RPC density was in "Nasal Inferior" and "Superior Nasal" segments, 48.9±3.2 and 49.9±3.1 %, respectively. Conclusion. The reference values of the optic disk and peripapillary retina parameters for senior Russian citizens, which were developed with RTVue XR Avanti (Optovue Inc., USA) device, can be used as diagnostic criteria for neuroophthalmological pathology.

1. Flammer J, Orgul S, Costa VP, et al. The impact of ocular blood flow in glaucoma. Prog Ret Eye Res 2002; 21: 359-93. DOI: 10.1016/S1350-9462 (02) 00008-3.
2. Conroy RM, et al. [SCORE project group]. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 2003; 24 (11): 987-1003.
3. Ding X, Lu L, Yang J, et al. The peripapillary retinal capillary density is highly correlated with its nerve fiber layer in normal population. Clin Hemorheol Microcirc 2019 Oct; p. 1-9. DOI: 10.3233/CH-180453.
4. Zabel P, Kaluzny JJ, Wilkosc-Debczynska M, et al. Comparison of retinal microvasculature in patients with alzheimer's disease and primary open-angle glaucoma by optical coherence tomography angiography. Invest Ophthalmol Vis Sci 2019; 60 (10): 3447-55. DOI: 10.1167/iovs. 19-27028.
5. Bochicchio S, Milani P, Urbini LE, et al. Diurnal stability of peripapillary vessel density and nerve fiber layer thickness on optical coherence tomography angiography in healthy, ocular hypertension and glaucoma eyes. Clin Ophthalmol 2019; 13: 1823-32. DOI: 10.2147/OPTH. S214877.
6. Maslova EV. Investigation of the role and place of OCT angiography in the diagnosis of glaucoma: PhD abstract. Moscow, 2016; 24 p. Russian (Маслова E.B. Исследование роли и места ОКТ-ангиографии в диагностике глаукомы: ав-тореф. дис. ... канд. мед. наук. М., 2016; 24 с).
7. Leveque РМ, Zeboulon Р, Brasnu Е, et al. Optic disc vascularization in glaucoma: value of spectral-domain optical coherence tomography angiography. J Ophthalmol 2016; 6956717-9.
8. Safonenko AYu, loyleva ЕЕ. Modern visualization technologies in diagnosing the optic nerve pathologies. Practical Medicine 2018; 114 (3): 156-60.
9. loyleva ЕЕ, Krivosheeva MS, Andrusyakova ЕР. ОСТ-angiography parameters of the macular area of the retina and optic nerve in healthy young people. Russian Ophthalmology of Children 2019; (3): 38-42.

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