Saratov JOURNAL of Medical and Scientific Research

2017, volume 13

Acousto-optical method of blood typing: the comparison of application of anti-A and anti-B monoclonal antibodies with standard hemagglutinating sera

Year: 2017, volume 13 Issue: №1 Pages: 022-028
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Doubrovski V.A., Medvedeva M.F.
Organization: Saratov State Medical University

The aim of the article is a comparison of resolution of the acousto-optical method for blood typing for two types of reagents: monoclonal antibodies and standard hemagglutinating sera. Materials and Methods: The influence of the concentrations of reagents (monoclonal antibodies and standard hemagglutinating sera), of blood sample, which is to be tested, as well as of the duration of the ultrasonic action on the biological object upon the resolution of acousto-optical method were investigated. The peculiarity of this work is the application of digital photo images processing by pixel analysis previously proposed by the authors. Results: The optimal experimental conditions to obtain maximum of the resolution of the acousto-optical method were found, it creates the prerequisites for a reliable blood typing. Conclusions: The present paper is a further step in the development of acousto-optical method for determining human blood groups.

Keywords: blood typin, digital imaging, erythrocytes, light absorption, monoclonal antibodie, RBC agglutination, RGB decomposition, sedimentation

Steroid compounds of phytogenic origin: scientometric research data of scientific and practical literature

Year: 2017, volume 13 Issue: №1 Pages: 014-021
Heading: Parmacology Article type: Review
Authors: Sukhanov А.Е., Buyuklinskaya O.V., Koptyaeva R.G.
Organization: Northern State Medical University

Steroid compounds of phytogenic origin are important in clinical medicine rendering anti-inflammatory, anti-prolifer-ative and antithrombotic actions. However, steroid compounds of phytogenic origin, in particular, steroid saponins are insufficiently studied from an identification position in tissues of vegetable organisms and methods of their physical and chemical analysis. The scientometric analysis of research data (abstract documents) containing an analytical array of scientific publications concerning isolation, selection, cleaning, identification and the quantitative definition of steroid saponins in tissues of the higher vascular plants in the abstract bibliographic database SciVerse Scopus (Elsevier publishing house) with use of criteria "key word" and "the key phrase" is provided in the article.

Keywords: scientometric analysis , steroid saponins

Characteristics of cases with poor outcomes of rendering medical care to children in six regions of the Russian Federation

Year: 2017, volume 13 Issue: №1 Pages: 010-013
Heading: Forensic medicine Article type: Original article
Authors: Erofeev S.V., Kupryushin A.S., Efimov А.А., vishnyakova Zh.S., Semina M.N.
Organization: Bureau of Forensic Medical Examination of the Ivanovo Region, Ivanovo State Medical Academy, Penza State University, Saratov State Medical University

Objective: to determine the characteristics of the outcome of the improper care for children, established during the commission of forensic examinations. Material and Methods. The material of this study was commission a forensic medical examination of the archives department of complex expertise of the Bureaus of Forensic Medicine of Moscow; the Moscow, Penza, Samara and Ulyanovsk regions, and the Republic of Mordovia, conducted from 1996 to 2006. The method of this study was a statistical database processing using Excel software application package. Results. The article presents the results of the analysis of 279 forensic medical examinations conducted by committees in the Bureaus of Forensic Medical Examination of Moscow; the Moscow, Penza, Samara and Ulyanovsk regions, and the Republic of Mordovia from 1996 to 2006. The examinations were conducted in connection with poor outcomes of rendering medical care to children. Conclusion. The number of conducted examinations correlates with the population of the region. The parents of the children affected by poor treatment mostly demand the medical staff to be prosecuted and more often make legal claims to the quality of emergency medical care; dissatisfaction with the quality of medical care is more often expressed by the parents of children under 3 years old. Legal claims are more often made against obstetricians-gynecologists, pediatricians, surgeons, infectious disease specialists and anesthesiologists-resuscitators. If the conclusion of the forensic medical examination committee on the nature of the pathological process coincides with the final clinical diagnosis, the provided medical care often turns out to be adequate; in cases of inadequate medical care the risks of moderate and grievous bodily harm as well as the patient's death are high.

Keywords: children, forensic medical examination conducted by a committee, medical care, poor outcome

Issues on optimization of primary health care for working patients with diagnosed hypertension

Year: 2017, volume 13 Issue: №1 Pages: 007-009
Heading: Health Service Organization Article type: Original article
Authors: Shulpina N.Yu., Erugina M.V, Sazanova G.Yu, Krom I.L.
Organization: Saratov State Medical University

Aim: to justify the ways of optimization of availability of primary health care for working-age patients with arterial hypertension. Material and Methods. The study of the availability of drug treatment of working-age patients with arterial hypertension was based on a survey of 409 patients and calculated the average cost of treatment of this group of patients for 1 month in accordance with the care standards. Results. On 01.06.2016, the cost of treatment for a patient with stage 1 hypertension amounted to 316.89 rubles per month, with 2 stage 652.68 rubles per month. 67% of patients of working age are unable to follow the doctor's recommendations and take the prescribed medicines. Conclusion. Provision of free medicines to patients with arterial hypertension of stages 1 and 2 and the formation of their commitment to preventive treatment causes a direct economic effect, which will be 7915979 rubles per year, and indirect economic effect of the decreased mortality from cardiovascular diseases, disability, reduce in disability days and increase of the gross domestic product.

Keywords: arterial hypertension, economic effectiveness, primary health care

Modern features of sexual behavior of students

Year: 2017, volume 13 Issue: №4 Pages: 582-585
Heading: Psychiatry Article type: Original article
Authors: Barylnik Yu.B., Kolesnichenko E.V., Guseva M.A., Titova A.A., Kuzina M.V.
Organization: Saratov State Medical University

The aim of the study is to identify the state of sex education and sexual behavior characteristics of students of Saratov State Medical University n.a. V. I. Razumovsky. Material and Methods. The anonymous survey of 214 students (160 female, 54 male) has been conducted. The median age of female respondents was 22±1.02 years, male respondents 21±1.21 years. Results. The issues concerning the sexual culture of today's youth and their reproductive plans have been discussed. Conclusion. The main trends of sexual behavior among medical students and intersexual characteristics of sexual culture among young people have been found out.

Keywords: students, sexual education, sexual behavior