Saratov JOURNAL of Medical and Scientific Research

№1, 2016, volume 12

Professor LevAleksandrovich Varshamov (dedicated to the 120-th anniversary of his birth)

Year: 2016, volume 12 Issue: №1 Pages: 87-89
Heading: Scientific schools and memorable dates Article type: Short message
Authors: Zavyalov A.I.
Organization: Saratov State Medical University
Summary:

The article presents biography of Professor LA Varshamov, his scientific and practical contribution to the development of Russian Medicine and to the training of academic staff at the Saratov Medical Institute.

Keywords: therapy, Professor L.A. Varshamov, biography

The art of communication of a higher school lecturer

Year: 2016, volume 12 Issue: №1 Pages: 82-86
Heading: Pedagogics and Education Article type: Short message
Authors: Kochetkova T.V., Chernenkov Yu.V., Bugaeva I.О., Dorogoykin D.L.
Organization: Saratov State Medical University
Summary:

The article is concerned with the communication skills of higher school teachers and significant aspects of theory and practice of pedagogical discourse.

Keywords: pedagogical discourse, the art of communication of a higher school lecturer

Sociological reflection of the phenomenon of compliance

Year: 2016, volume 12 Issue: №1 Pages: 77-81
Heading: Sociology of Medicine Article type: Author's opinion
Authors: Andriyanova Е.А., Usova E.N.
Organization: Saratov State Medical University
Summary:

The article explains the prospects of sociological interpretation of the phenomenon of compliance. The theoretical construct of the phenomenon of compliance is based on the allocation of social parameters of the therapeutic interaction as a particular social practice. The presence of the disease is seen as a sign of social, determined by the dynamics of social activity of the patient in the context of changes in the characteristics of social interaction. The author gives a sociological interpretation of the concept of compliance as the dynamic state of the area of therapeutic interaction. Substantiates the prospects of sociological reflection of compliance, which allows to carry out the social dimension of the conditions of stability/instability of the therapeutic interaction, predict and manage change behavioral strategies patients.

Keywords: compliance, factors of compliance of patients with chronic diseases, interaction of the subjects of the treatment process

Adherence to recommendations and effectiveness of glucose-lowering treatment in type 2 diabetes patients receiving insulin based in the Nizhny Novgorod region on data of mobile diagnostic and therapeutic centre "Diabetes mellitus"

Year: 2016, volume 12 Issue: №1 Pages: 71-76
Heading: Endocrinology Article type: Original article
Authors: Panova S.Yu., Petrov A.V., Strongin L.G.
Organization: N. Novgorod State Medical Academy
Summary:

Adherence to treatment is an important factor in diabetes management. Poor adherence may cause ineffective control, especially in insulin-treated patients. Aim of the study: to evaluate the adherence to nutrition, physical activity and self-monitoring in T2DM patients who do and do not receive insulin treatment. Materials and methods. 550 T2DM patients were examined as a part of mobile diabetes center in different areas of the Nizhny Novgorod region. Clinical examination results, HbA1c, creatinine and microalbuminuria were assessed. Adherence to treatment was evaluated by questionnaire Diabetes Self-Care Activities. Results. Insulin-treated patients had longer diabetes duration and worse HbA1 с level and similar levels of adherence related to diet, physical activity, foot care. Only for glucose self-monitoring was adherence higher. Best HbA1c values were observed in patients with adherence in middle region of 3-5 days. Conclusion. Long diabetes duration and worse glycemic control in insulin-treated T2DM patients is not associated with better adherence to treatment. This may be viewed as evidence on insufficient patients education and can be a potential target for improvement of glycemic control.

Keywords: adherence to treatment, insulinotherapy, type 2 diabetes

Surgical approach to patients with varicothrombophlebitis with undifferentiated dysplasia of connective tissue

Year: 2016, volume 12 Issue: №1 Pages: 66-70
Heading: Surgery Article type: Original article
Authors: Tsarev О.А., Anisimov A.Yu., Zakharov N.N., Korobov A.V.
Organization: Saratov State Medical University
Summary:

Aim: to study the peculiar features of clinical course of acute varicothrombophlebitis and surgical approach to patients with undifferentiated dysplasia of connective tissue. Material and Methods. The features of undifferentiated dysplasia of connective tissue, character of clinical course of acute varicothrombophlebitis, remote results for 94 patients, who had had Troyanov — Trendelenburg's operation, were studied. Results. 70 patients (74,5%) with acute varicothrombophlebitis demonstrated more than four phenotypic characters which showed the presence of undifferentiated dysplasia of connective tissue. 22 patients (31,4%) with acute varicothrombophlebitis with undifferentiated dysplasia of connective tissue were proved to have the discrepancy between localization of acute varicothrombophlebitis clinical evidences and level of proximal part of thrombus in the lumen of great saphenous vein. During the remote observation period, 66 patients (94,3%) with acute varicothrombophlebitis with undifferentiated dysplasia of connective tissue had pheblectomy, as there was vertical and horizontal pathological venous reflux. Out of 24 patients (25,5%) with acute varicothrombophlebitis without undifferentiated dysplasia of connective tissue, only four patients (16,7%) needed thesecond stage of surgical treatment, because 20 patients (83,3%), in 6 months after Troyanov — Trendelenburg's operation, demonstrated the restoration of functional consistency of valves of great saphenous and perforating veins. Conclusion. When determining the indications for urgent disconnection of saphenofemoral junction for patients with acute varicothrombophlebitis and also when choosing surgical treatment approach during remote observation period, it is reasonable to examine the phenotypic characters of undifferentiated dysplasia of connective tissue.

Keywords: varicothrombophlebitis, undifferentiated dysplasia of connective tissue, surgical tactics

Boerhaave's syndrome (case report)

Year: 2016, volume 12 Issue: №1 Pages: 61-66
Heading: Surgery Article type: Case report
Authors: Tainkin А.А., Bogdanova Т.М.
Organization: Saratov State Medical University
Summary:

The article describes a clinical case of spontaneous esophageal rupture. Raising awareness of physicians about this syndrome will facilitate its timely diagnostics.

Keywords: esophageal rupture, Boerhaave's syndrome

The clinical significance of the prevalence of parapancreatitis in pan-creonecrosis

Year: 2016, volume 12 Issue: №1 Pages: 57-60
Heading: Surgery Article type: Original article
Authors: Alexandrov D.A., Tolstokorov A.S., Sedov D.S.
Organization: Saratov State Medical University
Summary:

Tftea/m of the study is to determine the relationship of clinical surgical treatment options of degradation of retroperi-tonealfat. Material and Methods. We have analyzed the results of treatment of 1177 patients with necrotizing pancreatitis, taking into account the severity and characteristics of parapancreatitis. Statistical data processing was carried out by the program Statistica for Windows 6.0. using the Student's criterion. Results. The variety of clinical forms of pancreatic necrosis due to a combination of options lesions of the pancreas and retroperitoneal fat. The outcome of pancreatic necrosis is determined not only by the degree of destruction of the pancreas, but also features parapancreatitis. The allocation of limited and common prevalence of parapancreatitis was substantiated and specified. Conclusion. The effectiveness of the treatment of pancreatic necrosis is dependent on the development options of parapancreatitis which present the predictive and tactical value.

Keywords: pancreas, pancreatitis, parapancreatitis

Magnetic resonance imaging and biomarkers of serum and urine wile diagnostics of kidney cancer

Year: 2016, volume 12 Issue: №1 Pages: 52-56
Heading: Parmacology Article type: Original article
Authors: Nickolsky Yu.Ye., Chekhonatskaya M.L., Zakharova N.B., Popyhova E.B., Ponukalin A.N.
Organization: Saratov State Medical University
Summary:

Purpose: improvement of differential diagnostics of benign and malignant renal tumors basing on complex estimation of the results of MRTand the level of such biomarkers as vascular endothelial growth factor, monocyte chemotactic protein-1 and matrix metalloproteinase-9 in blood serum and urine. Material and Methods. A total of 106 patients including the main group of 60 patients with renal cancer (RC), the group of comparison of 16 patients with benign renal tumors and the control group of 30 practically healthy persons were examined. ELISA was employed for detection of the biomarkers in blood serum and urine. The tumors were diagnosed by MRT Results. The increase of the level of the biomarkers in blood serum and urine was registered independently of the character of neoplastic process; more significant increase was observed in patients with RC, especially at the early stages of the disease. Some peculiarities of changing of the level of the biomarkers depending on the dimensions of malignant tumors were found. Conclusion. At the early stages of RC complex detection of the abovementioned biomarkers in blood serum and urine can serve an additional clinical diagnostic and prognostic criterion.

Keywords: biomarker, magnetic resonance tomography, renal cancer

Parameters of quality of life of dental patients with various psychotypes

Year: 2016, volume 12 Issue: №1 Pages: 49-51
Heading: Stomatology Article type: Original article
Authors: Turusova Е.М., Bulkina N.V.
Organization:
Summary:

The aim is to study the effect of oral pathologies in the quality of life of patients, depending on the psychological characteristics of the individual. Material and Methods. The study involved 100 patients with included dentition defects and chronic generalized periodontitis. The index PMA, PI and hygiene index of Greene — Vermillion were identified in all patients. To assess the quality of life we used the OHIP-14 questionnaire. To assess the psychotype we used the modification of the questionnaire, developed in 2005, St. Petersburg. Results. There is a dependence of changes in the quality of life of dental patients with various psychotypes. Conclusion. Patients with a variety of personality types react differently to oral health, and it should be taken into account when choosing the tactics of conduct with patient data, as well as the choice of treatment and at all the stages of treatment.

Keywords:

Clinical case: paroxysmal tachycardia attack in a newborn with multiple heart rhabdomyomas

Year: 2016, volume 12 Issue: №1 Pages: 45-48
Heading: Pediatrics Article type: Case report
Authors: Chernenkov Yu.V., Pozgaleva N.V., Panina O.S.
Organization: Saratov State Medical University
Summary:

The purpose of the clinical observation is to study the early symptoms of multiple heart rhabdomiomas of a newborn; to draw the attention of specialists on one of the rarely occurred problems in the neonatal practice.

Keywords: multiple rhabdomyomas, neonatology, tachycardia