Saratov JOURNAL of Medical and Scientific Research

The value of composition and cytokine activity of wound discharge cells in patients with acute odontogenic inflammatory diseases of the maxillofacial region

Year: 2015, volume 11 Issue: №2 Pages: 173-177
Heading: Stomatology Article type: Original article
Authors: Lepilin A.V., Zakharova N.B., Fedotenkova D.A., Tereshkina N.E.
Organization: Saratov State Medical University

Purpose: to establish the diagnostic value of the immune cells composition and cytokine activity of the cells in wound discharge from patients with acute odontogenic inflammatory diseases of maxillofacial region. Materials and methods. A total of 31 patients with acute odontogenic inflammatory diseases of maxillofacial region were examined. The number of immune cells and pro-inflammatory cytokines content (IL1(3, MCP1, IL6, IL8, TNFa) in the wound discharge were determined. Results. It has been established that depending on the severity of the inflammatory process in maxillofacial region the immune cells composition and levels of pro-inflammatory cytokines are changing. Conclusion. Determination of the immune cells composition and level of cytokines in the wound discharge can be used for estimation of the character and severity of acute odontogenic inflammatory processes in the maxillofacial region.

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