2014, volume 10

This article represents results of pharmacoepidemiological research of H.pylori eradication treatment of adults and children in Volgograd. The aim was to determine H. pylori pharmacotherapy stereotypes and compare with international experts' recommendations. Material and Methods. There were analyzed CRFs of 94 adults and 132 children with H.pylori associated diseases in Volgograd region. Results. There were identified mistakes of treatment regimes and eradication control principles. Conclusion. The treatment of H.pylori infected adults and children in Volgograd does not match to international experts' recommendations.

The aim of the study was to investigate the clinical status of patients with atrial fibrillation (AF) and diabetes mellitus (DM) type 2 and to identify differences in the treatment of AF, conducted in the cardiology departments of multidisci-plinary teaching hospitals of the Saratov city. Materials and methods. A comparative retrospective analysis of 1041 pharmacoepidemiological solid history of patients with AF who were hospitalized in emergency, and in the planning department of cardiology of 2 multidisciplinary teaching hospitals of the Saratov city consecutively in a calendar year on the AF, recorded on an electrocardiogram. Results. Among all patients with AF, patients with DM accounted for 20.2%. Among them were women, they were younger, they developed fibrillation at a younger age, they differed more severe structural heart disease, among which was significantly greater with myocardial infarction, nearly all had symptoms of heart failure. Patients with DM performed less frequently cardioversion, and to monitor heart rate often preferred a combination of beta-blockers and digoxin. 100% of patients with DM had a higher risk of thromboembolic complications (91.9% without diabetes) in both groups, oral anticoagulants (OAC) prescribed often enough. Conclusion. DM was diagnosed in every fifth patient with AF, especially among women and patients with persistent AF and is associated with the presence of more severe organic heart disease compared with patients without DM. All patients on the background DM was a high risk of thromboembolic complications, i.e. OAC must be assigned in 100% of cases, but in the surveyed hospitals OAC were appointed only in 23% of cases.

Based on the published data the role of inflammation in development of pneumonia has been discussed. The role of inflammatory mediators and laboratory markers for diagnostics of community acquired pneumonia is evaluated, as well as prognostic role of different biomarkers of inflammation, available for clinical laboratories, but not widely used in daily clinical practice. Influence of Omega-3 polyunsaturated fatty acids on inflammatory processes and possibilities to use them in the treatment of community acquired pneumonia is also discussed in the study.

The aim of the study: to study the effect of mexidol content of ionized calcium and magnesium in erythrocytes and the number of circulating endothelial cells in patients undergoing surgery in the maxillofacial area. Material and methods. The intracellular concentration of calcium and magnesium was measured before the operation, in one, three and five days after the surgery with the help of cytochemical method. Mexidol (100mg) was administered intravenously as a single addition to the standard premedication. Results. After surgery, the intracellular calcium and magnesium content increased. After 24 hours, the magnesium level began to decline, and the calcium content in erythrocytes continued to grow. On day 5, the magnesium concentration in erythrocytes decreased below the initial level, and calcium levels remained significantly elevated. Number of endothelial cells in the blood increased immediately after surgery and magnesium-calcium balance and limits endothelial dysfunction. Mexidol continued growing, reaching a peak on day 5 after surgery. When using mexidol decreased levels of calcium and magnesium levels help prevent falls on the 5th day after surgery, decreased the number of circulating endothelial cells. Conclusion. Mexidol prevents postoperative magnesium violation.

The article presents the history review on the development of blood transfusion in Saratov, the organization and activity of regional station of blood transfusion during the war and the post-war years.

Представлены биографические данные о профессоре О. С. Глозмане, отражающие его вклад в развитие патологической физиологии и кафедры в Саратовском медицинском университете.

The aim of the article is to discuss the main stages of formation and development of Department of Health Service, Public Health and Medical Law of Saratov State Medical University. Scientific and practical contribution to the development of the national health over the years has been determined. The data on the current scientific and educational activities of the department have been highlighted.

This article analyzes the first experience in the implementation into the pedagogical process of one of the methods of active training — role playing. The need for intensification of medical education process is linked primarily to the rapid increase in the volume required to provide students with information and the lack of training time. The analysis showed that the game significantly increases the level of students' knowledge, but require substantial modernization of the educational process.

The article is devoted to the innovations in the higher medical education. Particular attention in this sphere is paid to the detailed analysis of the subject as a mechanism of cognition and psycho-emotional aspect. It should be noticed that the development of the university education demands the integration of functional systems to study the general medicine and the art of healing. In conclusion it has been found out that the new methodological approach is necessary to bring the teacher closer to the subject particularly to integrate the relation of the opposites.

Despite the success of therapeutic treatment of peptic ulcer and the introduction of endoscopic technologies, the problem of peptic ulcer hemorrhage remains valid. A large number of publications in foreign literature are dedicated to epidemiology and prevention of bleeding, evaluation of modern tactics and search for new methods of treatment. The works relating to organization of aid to patients with peptic ulcer bleeding are of particular interest. According to the recent data not all clinics even in economically developed countries manage to follow the recommendations of an international consensus-2010 for non-variceal bleeding treatment of upper gastrointestinal tract. Among the causes of non-compliance of international recommendations there are subjective and objective factors, the understanding of which can significantly affect the optimization of aid to patients with peptic ulcer bleeding.