Saratov JOURNAL of Medical and Scientific Research

The treatment of H.pylori infected adults and children in Volgograd: pharmaco-epidemilological investigation

Year: 2014, volume 10 Issue: №1 Pages: 185-188
Heading: Parmacology Article type: Original article
Authors: Magnitskaya O.V., Ponomareva Ju.V., Ryazanova A.Ju., Yefimova A.A., Chechetkina Je.M., Idelbaeva E.S., Bukina N.Ju., Volodina L.A., Kartashova T.R., Gorjushkina A.A..
Organization: Volgograd State Medical University

This article represents results of pharmacoepidemiological research of H.pylori eradication treatment of adults and children in Volgograd. The aim was to determine H. pylori pharmacotherapy stereotypes and compare with international experts' recommendations. Material and Methods. There were analyzed CRFs of 94 adults and 132 children with H.pylori associated diseases in Volgograd region. Results. There were identified mistakes of treatment regimes and eradication control principles. Conclusion. The treatment of H.pylori infected adults and children in Volgograd does not match to international experts' recommendations.

1. Ivashkin VT, Maev IV, Lapina TL, et al. Guidelines of the Russian Gastroenterological Association on diagnostics and treatment of Helicobacter pylori infection in adults. RJGHC 2012; 22 (1): 87-89; 2. Guidelines of the Russian Gastroenterological Association on diagnostics and treatment of ulcer disease. URL: (27.02.2014); 3. Malfertheiner Р, Megraud F, O'Morian CA, et al. Management of Helicobacter pylori infection the Maastricht IV/ Florence Consensus Report. Gut 2012; 61: 646-664; 4. Koletzko S, Jones NL, Goodman KJ, et al. H pylori Working Groups of ESPGHAN and NASPGHAN. Evidence-based guidelines from ESPGHAN and NASPGHAN for Helicobacter pylori infection in children. J Pediatr Gastroenterol Nutr 2011; 53 (2): 230-43; 5. Shcherbakov AP, Shcherbakov PL. H. pylori infection management in children (evidence based guidelines ESPGHAN and NASPGHAN 2010). Lechashchiy vrach 2011; (6). URL:; 6. Maev IV, Samsonov АА, Golubev NN, et al. Helicobacter-associated Form Of Peptic Ulcer Of Stomach And Duodenum: Problems Of Therapy. Pharmateka 2011; (2): 10-17; 7. Kornienko YeA, Parolova Nl. Antibiotic resistance of Helicobacter pylori among children and treatment selection. Current pediatrics 2006; 5 (5): 46-50; 8. Pharmacoepidemiologic researches of ulcer disease. In: Applied pharmacoepidemiology/ General ed. of Petrov VI. Moscow: GEOTAR-Media, 2008; p. 298-304; 9. Fuccio L, Minardi ME, Zagari RM, et al. Meta-analysis: duration of first-line protonpump inhibitor based triple therapy for Helicobacter pylori eradication. Ann Intern Med 2007; (147): 553-662.

2014_01-01_185-188.pdf246.52 KB

No votes yet