№3, 2013, volume 9

Aim: to analyze the erbium laser effects in oral surgery in patients with the risk of bleeding. There were selected 2 groups of patients for oral surgery treatment. Materials and methods. The first group included 31 patients with bleeding risk. In this group erbium laser radiation was used for the cut and tooth socket conditioning after tooth extraction. The second (control) group of 43 patients without concomitant pathology was determined for conventional surgical treatment. Results. In the first group there was no postoperative bleeding, post-surgical pain and infection were prevented with no need for analgesics, and the wounds epithelization took 1-3 days. It takes less time than in control group. Conclusion. Application of erbium laser is a modern method which can be successfully used in surgical treatment of patients with the risk of bleeding.

Purpose: to study the properties of nanostructured coatings in orthodontic implants. Material and methods. Low and average molecular mass chitosan, 3-amynopropil-3-methoxysylan and suspensions of 5 nm and 10 nm gold nano-spheres stabilized with natrium citrate were used for nanocomposed surfaces. 2mg/ml polyethylenamin water solution was used for making the underlayer before putting polyion coverage using «POLYION-1M». The polyion covering dynamics was studied by polyquartz weighing method. Morphology of created layers was studied with atomic microscopy, elements were studied by secondary ion mass-spectrometry. Results. The best transmission among structures of chito-san/metals was showed by low molecular mass of chitosan and 8-1 Onm nanoparticles of metals. Analysis of roughness of surface shows that nanoparticles of gold make the most solid surface on 3-amynopropil-3-methoxysylan underlayer. Conclusion. The development of biocomparative materials in maxillofacial surgery is considered to be effective method of decreasing the risk of post-operative inflammatory complications by local antibacterial effect.

Objective: To assess the importance of using the new system Quick Sleeper for local anesthesia, to highlight benefits of quick and comfortable anesthesia. Material and Methods. The examination of effectiveness, convenience of this kind of anesthesia has been carried out. Results. All patients, taking part in this examination, confirmed more comfortable condition after this anesthesia than conductor and infiltration methods of anesthesia. The effect of anesthesia is better than after conductor anesthesia. Conclusion. This technology guarantees equal introduction and spread of anesthetic, independently of tissue density, eliminating the risk of carpule breakage.

The purpose of the work is to prescribe combined treatment in order to determine the efficiency of cycloferon liniment. Materials and methods. 80 patients suffering from such inflammatory disease of parodentium as herpetic stomatitis and periodontitis have been examined and treated. Results. Cycloferon liniment used in the combined treatment of stomatitis and periodontitis reduces the infection load in gingival pockets, decreases local inflammation, normalizes immunity parameters, decreases endotoxemia and reduces relapse rates. Conclusion. Cycloferon liniment is an efficient medication restoring the parameters of local nonspecific immune response.

Objective: to develop a questionnaire for assessing the level of dentophobia and dynamics of the relationship in the «doctor-patient» in the course of treatment and to conduct its clinical trials. Material and Methods. 90 patients aged 26-56 years with chronic generalized periodontitis have been examined. The research has been conducted by Hospital Anxiety and depression (HADS) questionnaire to determine the level of dentophobia; psychophysiological testing was carried out on the hardware-software complex (APC) «NS-Psychotest» (LLC «Neurosoft», Russia, Ivanovo, 2007). Clinical examination included examination of the mouth and the index of assessment of hard tissue of teeth and peri-odontal tissue: a defining simplified oral hygiene index (UIG), sulcus bleeding index (IR), gingival index (PMA). The survey was carried out before the treatment and 3 months after the treatment. Statistical analysis was performed in the program Statistica. Using non-parametric methods (Wilcoxon test, criterion A2, Spearman correlation coefficient). Statistically significant differences with p < 0,05 were considered. Results. The development of the questionnaire was carried out in accordance with all generally accepted standards. The initial testing was performed easily by patients. During the clinical trials visible results of the proposed questionnaire were obtained that proved its sensitivity to the changes in dental and psychological status of the oral cavity. Conclusion. The practical application of the questionnaire determines the level of dentophobia during the first visit. The data of the questionnaire identify the differentiated deontological approach. It improves the relationship with the patient, reduces his level of dentophobia. The reduced dentophobia promotes compliance and psychologically comfortable communication in the doctor-patient system, which also contributes to the prevention of emotional burn out among dentists.

Objective: to study the adhesion of oral microflora and the degree of penetration into the structure of the basis of structural polymers in a comparative perspective. Material and methods. The object of the study is based on samples representative of the modern basis of polymers subjected to contamination by microorganisms in the experiment. Assessment of the quality of the resulting surface samples of basic dental polymer after polishing using a scanning ion microscope. The study of adhesion of microorganisms on the surface of the samples was performed in the experiment in vitro by the method of V. N. Zarev, 2006. Fluorescence imaging was held to study microbial penetration into the interior of polymers of microorganisms using a confocal laser scanning microscope. Results of the study revealed a degree of adhesion and penetration of microorganisms to the surface and the structure of the base polymer. Conclusion. The findings suggest the importance of final basic polymers. Thermoplastic polymers are characterized by complex processing, concerning promote greater adhesion and infiltration of microorganisms into the interior of the construction in comparison with the acrylic polymers.

The purpose: to improve the treatment of patients with orthopedic dento-alveolar deformation of dentition and occlusion by using a range of methods of psychophysiological support of patient care. Material and methods. The study included 86 patients, men and women aged from 18 to 49 years with dento-alveolar deformation of dentition and occlusion. The study used clinical, anthropometric, radiological, photometric and static methods. At each stage of treatment, to investigate the characteristics of the functional status of patients methods of SAN, IPC «adaptive», self-esteem of patients by developed questionnaire were used. Results. A direct, reliable, moderate correlation has been established between the estimates that have given quality of care to patients with a regularity of the complex of psychophysiological methods proposed. Conclusion. A positive impact of the proposed complex of psychophysiological methods to support the functional characteristics of the patients and their assessment of the treatment, and the effectiveness of orthopedic treatment have been determined.

Molecular markers of destruction of periodontal tissue and alveolar bone belong to the mediators, participating in maintenance of chronic inflammatory process in the clinical attachment. Purpose: To reveal changes of cytokine profile of gingival fluid and proliferative activity of cells of gum at patients with inflammatory periodontal diseases. Material and methods. Immunohistochemical research of biopsy gum material of 70 patients with periodontal disease with monoclonal antibodies: Ki-67 (marker of proliferative activity of cells), Bcl-2 (apoptosis marker); method of the solid-phase immunofermental analysis for level definition interleukin -6, 10, 12, 18 in gingival fluid (about — and anti-inflammatory markers). Results. It is shown that level definition of cytokines in gingival fluid allows to monitor the activity of the inflammatory process in the periodontal tissues, and the morphometric analysis of periodontal cells reflects degree of its weight. Conclusion. The use of molecular markers in inspection of patients with periodontal disease is the informative method, allowing to predict development and course of chronic periodontal disease.

The aim of the research was the study of the cell proliferation indices of the gum epithelial cells in patients with parodentium inflammatory diseases accompanied by gastroesophageal reflux disease (GERD). Material and methods. 160 patients were examined, 60 patients with parodentium inflammatory diseases accompanied by NEGERD, 40 patients with parodentium inflammatory diseases accompanied by GERD. The comparison groups consisted of 40 patients with diseases of parodentium without esophagus pathology and 20 healthy persons. Results. On the basis of the conducted clinical-endoscopic, immune-histological and morphological examinations it was established that gingivitis and periodontitis are successive stages of disturbance of the cellular homeostasis of gum epithelial cells. Conclusion. The enhancement of the processes of proliferation and apoptosis promotes the progression of the structural alterations in the tissues of parodentium and oesophagus and may serve as additional diagnostic and prognostic criteria of the diseases of parodentium accompanied by GERD.

Objective: to study the qualitative and quantitative composition of microflora in the root canals of teeth in the treatment of patients with chronic apical periodontitis. Material and methods. The efficiency of the treatment of chronic apical periodontitis was determined in two groups of patients: the main group 1 (18 persons) and comparison group 2 (11 persons), by examining culture-biochemical properties of the contents of the teeth root canal (RC), the concentration of total protein and leukocyte. For endodontic treatment in group 1 the «Radent» was used and in group 2 was used «Krezodent.» Results. In group 1 suppression of anaerobic microorganisms was found and the reduce of occurrence of streptococci, the growth of Candida, Enterobacterium and Corynebacterium did not detected. In group 2, rising Candida, pyogenic streptococci, staphylococci and anaerobic microorganisms was found. The concentration of total protein and white blood cells in teeth RC contents in groupl decreased significantly and in group 2 contents did not change. Conclusion. The pathological process in the periodontium under chronic apical periodontitis supported predominantly coccal and anaerobic microflora, with exacerbation prevail streptococci, Neisseria and enterobacteria. Inflammation of the periodont supports leukocyte cells that synthesize the protein molecules. «Radent» has a strong antibacterial and anti-inflammatory effect.