№2, 2009, volume 5

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Article is devoted to the Ninetieth Anniversary of Creation of the «substantia nigra» theory of Parkinson’s disease by famous Saratov scientist K. N. Tretjakov.

Biographic facts about Professor E.A.Tatarinov are presented in the article. These data give close attention to his contribution to the development of Department of Pathological Physiology at Saratov State Medical University.

The article represents the history of the first University Therapeutical Department, that was organized in September 1911, stages of it’s development and scientific schools foundation.

In this article the authors demonstrate the results of use the contemporary forms of students’ self-work organization.

Pathogenesis mechanisms of tuberculosis have been considered. It is shown, that important place in pulmonary tuberculosis therapy should belong to the means of pathogenetic therapy directed to the improvement of pulmonary circulation and living conditions of cells of lung parenchyma, restoration of local tissue immunity, including macrophage system and other defensive mechanisms, synthesis and secretion stimulation of surfactant, and use of surfactant medications.

To study the variants of the clinical course of varicose disease of patients with different grades of connective tissue dysplasia intensity. The results of the examination and treatment of 280 patients with various forms of varicose disease have been studied. The degree (grade) of connective tissue dysplasia intensity has been estimated. The values characterizing flow and coagulation properties of blood, functional activity of thrombocytes have been studied. Morphological, histological, histochemical check studies of extirpated varicose modified veins of patients with various grades of connective tissue dysplasia intensity have been held. The conducted check studies have shown that lower limbs varicose disease of patients with evident connective tissue dysplasia is characterized by early evidence of clinical signs, rapid advance of the disease, widely spread damage of veins and complicated course caused by the weakness of the connective-tissular carcass of a vein wall as well as by evident disorders of flow and coagulation properties of blood. Patients with varicose disease secondary to the evident (expressed) connective tissue dysplasia are in the risk group of palindromia, thrombus complications and trophesies development, need dispensary observation for proper treatment in good time.

The purpose is to reveal patterns of variability of thoracic vertebrae size characteristics for adequate selection of standard sizes and orientation of corrective hardware introduction. Materials include preparations of vertebrae of 60 skeletons from the collection of Department of Human Anatomy, Saratov State Medical University and 110 computer tomograms in adults without visible backbone pathology, 200 computer tomograms of backbone traumas from archives at Saratov Scientific Research Institute of Traumatology and Orthopedics. The analysis of results of surgical treatment of 288 patients with backbone damages have been carried out from 1995 till 2008. Since 2003 preoperative planning at 160 patients has been done taking into account anatomo-topographic vertebrae sizes. Optimum selection of ventral designs has been carried out taking into account the sizes of vertebral bodies (front, back, lateral heights, sagittal and frontal diameters of vertebral bodies). It is necessary to consider the sizes of back structures (thickness and height of arches, pediculo-regional length, height, width, corners of convergence and inclination of pedicles of vertebrae).

The method of global electromyography has been used for the evaluation of 231 patients aged from 16 to 74 (43,7±0,8) with bilateral osteoarthrosis of major joints of lower extremities I-III degrees before the course of conservative treatment, immediately after the end of conservative treatment and in three months. Conservative treatment of patients with osteoarthrosis of major joints of lower extremities has been shown to cause restructuring of EMG patterns of maximal voluntary muscle contraction in lower extremities accompanied by decreased asymmetry of activity levels in muscle pairs and less observations of pathologically changed EMG that results in improved functional condition of the locomotor system.

Injury of both superficial and deep tendons of fingers flexors needs to carry out tendinous plasty with excision of distal part of superficial flexor muscle tendon. Use of length measuring method for tendinous transplant allows us to avoid the flexion contracture in future and appearance of functional insufficiency of flexion during postoperative period and rehabilitation of patient.