Saratov JOURNAL of Medical and Scientific Research
Home

Functional resistance of enamel and the phenomenon of transtegumental fluid transport

Year: 2011, volume 7 Issue: №1 Pages: 211-216
Heading: Stomatology Article type: Original article
Authors: Okushko V.R. Okushko R.V. Ursan R.V.
Organization: Dnester State University n.a. T.G. Shevchenko
Summary:

Current data related to transport of fluid through the covering tissue formations (skin, nail plate, dental enamel, gum valley) are being analyzed. A supposition is made of transtegumental fluid transport (TFT) as a general biological regularity which is specifically manifested in tissues of different functional purposes. Depending on the peculiarity of the organ, the tooth performs the TFT providing functional resistance of the enamel, whose level is clinically detected in the «test of enamel resistance» (TER) used in modern research. The article draws attention to the reasonability of an in-depth study of the tooth physiology, where the central element is TFT. This phenomenon is of interest both from fundamental and highly practical standpoints. Identification of seasonal periods in the functional resistance decline makes it possible to get a distinct effect by means of concentrating prevention efforts on this. The TER sample, as well as other transtegumental fluid transport patterns, is to find place in the system of personalized predictive approach to caries diseases

Keywords: tooth physiology, skin, predictive medicine, personalized medicine, nail, gum valley, dental enamel, caries

References (including transliteration from Cyrillic to Roman script)

1.  Okushko V. R. Fundamental'naja odontologija i karioznaja bolezn'//DentArt 2010. №3. S. 31-34.
2.  Baranov V. S. Programma «Genom cheloveka» kak nauchnaja osnova profilakticheskoj mediciny // Vestnik RAMN.
2000.  №10. S. 27.
3.  Jemec G.B., Agner T., Serup J. Transonychial water loss: relation to sex, age and nail-plate thickness // Br. J. Dermatol. 1989. Vol. 121(4). P. 443-446.
4.  McCarthy D.J. Anatomic considerations of the human nail // Clin. Podiatr. Med. Surg. 2004. Vol. 21. P. 477-481.
5.  Transepidermal Water Loss Does Not Correlate with Skin Barrier Function In Vitro / R Chilcott, S Dalton., A Emmanuel, [et al]//J. oflnvestig. Derm.-2002. Vol. 118. P. 871-875.
6.  Leonora J., Tieche J.M., Celestin J. Physiological factors affecting secretion of parotid hormone //Am. J. Physiol. 1987. Vol. 252. P. 447.
7.  Steinman R.R. Biologic activity in the tooth in health and disease // Sotr. Contin. Educ. Dent. 1984. Vol. 9. P. 722-728.
8.  Okushko V. P. Osnovy fiziologii zuba. M.: Newdent, 2008. 344 s.
9.  Pikovskij V. Ju., Kozlov A.V. Obwee peregrevanie (teplovoj udar). [Jelektronnyj resurs] // Medicinskij vestnik. 2007. № 3. URL: http://medvestnik.rU/2/0/8572/view.html (data obrawenija 10.12.2010).
10.  Hjesset Dzh. Vvedenie v psihofiziologiju. - M.: Mir, 1981.244 s.
11.   Fischbarg G. Fluid Transport Across Leaky Epithelia: Central Role of the Tight Junction and Supporting Role of Aquaporins//Physiol. Rev. 2010. Vol. 90. - P. 1271-1290.
12.  KrbnauerO, Gfesser M., Ring J., Abeck D. Transonychial water loss in healthy and diseased nails //Acta Derm. Venereol.
2001.  Vol.81. P. 175-177.
13.    Levin J., Maibach H. The correlation between transepidermal water loss and percutaneous absorption: an overview// Nature 2005. Vol. 103. P. 291-299.
14.  Driscoll M.S., Jane M. Hormones, nevi, and melanoma: An approach to the patient // J. of Am. Ac. of Derm. 2007. Vol. 57. P. 919-931.
15.  Bergman G, Linden L. Techniques for microscopic study of enamel fluid in vivo. //J. Dent. Res. 1965. Vol. 44. P. 1409.
16. Lar'kova I. A., Ksenzova L. D. Atopicheskij dermatit u detej: sovremennye aspekty uhoda za kozhej // Pediatrija. 2009. - №3. S. 45-49.
17.  Huang F.L., Roop D., DeLuca L.M. Vitamin A deficiency and keratin biosynthesis in cultured hamster trachea // In Vitro
Cellular & Developmental Biology - Plant. 1986. Vol. 22(4). P. 223-230.
18.   Shafer L., Kragballe K. Abnormalities in epidermal lipid metabolism in patients with atopic dermatitis // J. Invest. Dermatol. 1991. Vol. 96. P. 10-15.
19.  Kim S., Wong P., Coulombe PA. A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth // Nature. 2006. Vol. 441. P. 362-365.
20.  Murdan S., Hinsua D., Guimiera M. A few aspects of transonychial water loss (TOWL): Inter-individual, and intra-individual inter-finger, inter-hand and inter-day variabilities, and the influence of nail plate hydration, filing and varnish // Eur. J. of Pharm. and Biopharm. 2008. Vol. 70. P. 684-689.
 

AttachmentSize
2011_01_Прил_211-216.pdf457.26 KB
All articles of the authors: Ursan R.V., Okushko V.R., Okushko R.V.

No votes yet