Multiform exudative erythema diagnosed as Stevens — Johnson syndrome
Heading: Тhematic supplement Article type: Case report
Authors: Shchava S.N., Serdyukova E.A., Ivanova I.N.
Organization: Volgograd State Medical University
The article presents a case of the development of a bullous form of exudative erythema multiforme, which was erroneously diagnosed as Stevens — Johnson syndrome. This observation demonstrates the difficulties encountered in the differential diagnosis of dermatoses having the similar etiopathogenesis and identification of manifestations. The authors presenting a clinical case focus on those symptoms that allow, in the event of a diagnostic examination, to exclude the most severe skin disease — Stevens — Johnson syndrome. The knowledge of the data will prevent practising physicians from medical diagnostic and tactical errors.
Bibliography:
1. Bulgakova Al, Hismatullina ZR, Zatsepina MV, Kudryavt-seva JA. On the clinical course of multiforme exudative erythema of the oral cavity (literature review). Parodontologiya. 2020; 25 (1): 71-4.
2. Shwe S, Kraus CN, Linden KG, et al. Erythema multiforme in a child with Kawasaki disease. JAAD Case Rep. 2019; 5 (4): 386-8. DOI: 10.1016/j.jdcr.2019.02.013.
3. Federal clinical guidelines. Dermatovenereology 2015: Skin diseases. Sexually transmitted infections. 5th ed., revised, and additional. Moscow: Business Express, 2016; 768 p.
4. Grigorev DV. Erythema multiforme exudative, Stevens — Johnson syndrome and Lyell's syndrome — a modern interpretation of the problem. Russian Medical Journal. Dermatology. 2013; (22): 1073-83.
5. Olteanu С, Shear NH, Chew HF, et al. Severe physical complications among survivors of Stevens — Johnson and toxic epidermal necrolysis. Drug Safety. 2018; 41 (3); 277-84. DOI: 10.1007/S40264-017-0608-0.
6. Shchava SN, Serdyukova EA. Features of the course and treatment of erythema multiforme exudative at the present stage. Medicinal Herald. 2016; 4 (64): 41-3.
7. Fujimura Т, Kambayashi Y, Hidaka Т, et al. Severe erythema exudative multiforme developing from advanced melanoma treated with dabrafenib and trametinib followed by nivolumab. J Dermatol. 2018; 45 (2): e35-6. DOI: 10.1111 /1346-8138.14085.
8. Brito FJF, Rodriquez R. Exudative erythema multiforme due to cyclobenzaprine. J Investig Allergol Clin Immunol. 2016; 26 (4): 265-6. DOI: 10.18176/jiaci.0064.
9. Dalipi ZS, Dragidella F, Dragidella DK. Oralmanifestationsof exudative erythema multiforme in a patient with COVID-19. Case Rep Dent. 2021; (2021): 1148945. DOI: 10.1155/2021/1148945.
10. Khamaganova IV, Malyarenko EN, Denisova EV, et al. Mistakes of diagnostics in pemphigus vulgari: case report. Russian Journal of Skin and Venereal Diseases. 2017; 20 (1): 30-3. DOI: 10.18821/1560-9588-2017 -20-1-30-33.
11. Karachyova YuV, Prohorenkov VI, Gajdash AA, et al. Bul-lous skin lesions: problems of nosology and differential diagnosis. Siberian Medical Review. 2007; (3): 10-5.
12. Dyubkova ТР, Zhernosek VF. Differential diagnosis of Stevens — Johnson syndrome/toxic epidermal necrolysis and erythema multiforme in children. Meditsinskiye novosti. 2014; (2): 43-7.
| Attachment | Size |
|---|---|
| 2022_04-2_742-744.pdf | 526.42 KB |



