Saratov JOURNAL of Medical and Scientific Research

Endophthalmitis prevention after cataract phacoemulsification (review)


Abstract. Objective: to analyze the literature data on the endophthalmitis incidence and prevention after cataract phacoemulsification. Literature search was carried out in the Russian (RSCI) and international (PubMed) databases using the keywords "cataract phacoemulsification", "endophthalmitis", "antibacterial agents", "intracameral administration of antibiotics". A total of 554 sources were analyzed with further use of systematic review filters and authors' knowledge on the topic (48 sources were selected for review). The duration of the retrospective analysis was 10 years (2013-2022). Conclusion. The incidence of endophthalmitis in the traditional use of antibacterial drugs (aminoglycosides, fluoroquinolones in drops) ranged from 0.066 to 0.206%; when using these drugs in combination with intracameral administration of antibiotics (cefuroxime, moxifloxacin) — from 0.015 to 0.035%. The data presented in the literature correspond to both traditional unilateral sequential cataract surgery and immediate sequential bilateral cataract surgery the relevance of which may be due to the complex epidemiological situation.

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