Quality of life after various vitrectomy technologies in patients with proliferative diabetic retinopathy on hemodialysis
Heading: Тhematic supplement Article type: Original article
Authors: Belikova E.I., Golovin A.S., Kozhukhov A.A., Eskina E.N., Kumar V.
Organization: Academy of Postgraduate Education under the Federal Scientific and Clinical Center of the Federal Medical Biological Agency of Russia, Leningrad Regional Clinical Hospital, Saint Petersburg, Russia, Peoples' Friendship University of Russia
Abstract. Objective: comparative assessment of quality of life (QoL) after various vitrectomy techniques in patients with proliferative diabetic retinopathy on hemodialysis. Material and methods. 72 patients (mean age 57.4±2.2 years) requiring regular hemodialysis sessions were under observation. Patients were divided into two groups (36 patients, 36 eyes) equal in age, gender and severity of proliferative diabetic retinopathy: the main group included underwent vitrectomy following the developed technique and the control group included underwent the traditional surgery. QoL investigation was performed according to a special (Assessment of Quality of Life in Patients with Vitreoretinal Pathology, QoL-20) and general (Visual Function Questionnaire 25, VFQ-25) questionnaires before and one month after surgery. Results. QoL after vitrectomy was significantly increased by both questionnaires. Comparatively, the greatest positive dynamics was revealed in the main group patients compared to the control group on the VFQ-25 questionnaire (by 20.0%, p=0.013) and the QoL-20 questionnaire (by 47.5%, p=0.008). Conclusion. The developed technique of vitrectomy in patients with proliferative diabetic retinopathy undergoing hemodialysis was characterized by higher clinical effectiveness as shown by a comparative dynamics of QoL indicator, especially according to a special questionnaire QoL-20 designed for vitreoretinal pathology.
Bibliography:
1. Тео ZL, Tham YC, Yu M, et al. Global prevalence of diabetic retinopathy and projection of burden through 2045:
Systematic review and meta-analysis. Ophthalmology. 2021; 128 (11): 1580-91. DOI: 10.1016/j.ophtha.2021.04.027.
2. Fursova AZh, Vasil'eva MV, Derbeneva AS, et al. Optical coherence tomography angiography in the diagnosis of retinal microvascular changes in chronic kidney disease (clinical observations). The Russian Annals of Ophthalmology = Vestnik oftal'mologii. 2021; 137 (3): 97-104 DOI: 10.17116/oftalma202113703197.
3. Thomas RL, Halim S, Gurudas S, et al. IDF Diabetes Atlas: A review of studies utilising retinal photography on the global prevalence of diabetes related retinopathy between 2015 and 2018. Diabetes Res Clin Pract. 2019; 157 (11): 107840. DOI: 10.1016/j.diabres.2019.107840.
4. Ng H, Vermeer KA, van Meurs JC, La Heij EC. Visual acuity inadequately reflects vision-related quality of life in patients after macula-off retinal detachment surgery. Invest Ophthalmol Vis Sci. 2020; 61 (10): 34. DOI: 10.1167/iovs.61.10.34.
5. Yuldasheva NM. Proliferative diabetic retinopathy: new aspects of pathogenesis, substantiation of the system of sparing vitreoretinal surgery and complex pharmacotherapy DSc dissertation. Moscow, 2014; 308 с
6. Golovin AS, Belikova El. Scientific substantiation, development, evaluation of the safety and clinical efficacy of vitrectomy technology in patients with severe forms of proliferative diabetic retinopathy who are on hemodialysis. Ophthalmology in Russia. 2022; 19 (4): 746-52.DOI: 10.18008/1816-50 95-2022-4-746-752.
7. Karapetov GYu. Scientific substantiation, development and evaluation of the clinical and diagnostic effectiveness of the methodology for studying the patient's QoL in various types of vitreoretinal pathology. PhD dissertation. Moscow, 2017; 124 p.
8. Malyshev AV Complex system of personalized measures to improve the clinical and functional efficiency of surgical treatment of vitreoretinal pathology. DSc dissertation. Moscow, 2015; 212 p.
9. Ovechkin IG, Kovrigina El, Konovalov ME, Kumar V Quality of life study in ophthalmic practice. Ophthalmology Journal. 2021; 14(3): 61-70.
| Attachment | Size |
|---|---|
| 2022_04-1_651-653.pdf | 317.21 KB |




