Cardiometabolic risk factors and target-organ damage in women with hypertensive disorders during pregnancy 10 years and more after delivery
Year: 2022, volume 18 Issue: №3 Pages: 359-363
Heading: Cardiology Article type: Original article
Authors: Tarasova О.А., Chulkov V.S., Starodubtseva I.A.
Organization: South Ural State Medical University, Voronezh State Medical University n.a. N.N. Burdenko
Heading: Cardiology Article type: Original article
Authors: Tarasova О.А., Chulkov V.S., Starodubtseva I.A.
Organization: South Ural State Medical University, Voronezh State Medical University n.a. N.N. Burdenko
Summary:
Objective: to assess cardiometabolic risk factors and target-organ damage in women with hypertensive disorders during pregnancy 10 years and more after delivery. Material and methods. A cross-sectional study based on a prospective cohort study. The study included 66 women divided into two groups: group 1 — with a history of hypertensive pregnancy disorders (n=33), group 2 (control) —with a history of normotensive pregnancies (n=33). Results. The frequency of cardiometabolic risk factors in group 1, including arterial hypertension (87.9 vs6.1%, p=0.019), abdominal obesity (36.4 vs 12.1%, p=0.042), increased uric acid levels (18.2 and no cases in group 2, p =0.012) and impaired fasting glycemia (15.2 vs 3.0%, p=0,197) and a higher laboratory markers of insulin resistance (HOMA-IR index 1.47 [0.55-1.62] vs 0.40 [0.27-0.67], p<0.001) were higher compared with group 2. Metabolic syndrome was detected in every third case (36.4%), and stage II hypertension was found in every second woman with hypertension (44.8%) in group 1 (44.8%) and absence rate in the control group. Conclusion. Women who had hypertensive disorders during pregnancy are at high risk of developing metabolic syndrome with target-organ damage compared to normotensive women during pregnancy.
Keywords: arterial hypertension, cardiometabolic risk factors, hypertensive disorders during pregnancy, target-organ damage
Bibliography:
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