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Risk analysis of carotid endarterectomy complications in the early period after stroke

Year: 2022, volume 18 Issue: №3 Pages: 341-349
Heading: neurosurgery Article type: Original article
Authors: Yakubov R.A., Khairutdinov A.I., Tarasov Yu.V., Valiullin D.Kh., Yakubova V.T., Komarov R.N., Shchanitsyn I.N., Bazhanov S.P.
Organization: N. V. Sklifosovsky Research Institute for Emergency Medicine, Saratov State Medical University, State Autonomous Health Institution of the Republic of Tatarstan "Emergency Hospital"
Summary:

Objective: analysis of the predictors of carotid endarterectomy complications in early poststroke recovery. Material and methods. A retrospective analysis of the results of early carotid endarterectomy in 88 patients with symptomatic stenosis of the internal carotid artery stenosis (according to NASCET) up to 30 days after stroke was performed. The analysis of stroke, myocardial infarction, and 30-day mortality predictors was univariate and regressive. Results. Ipsi-lateral stroke was observed in 3 patients (3.4%) and was fatal in one case. The univariate analysis revealed female sex (p=0.009; OR=5.31; CI95%: 3.42-8.26), stenosis of the operated artery <70% (p=0.037; OR=3.15; CI95% 2.31-4.29) and multiple lesions on computed tomography/magnetic resonance imaging (p=0.04; OR=16.80; CI95%: 1.39-205.3) to be significant risk factors, while the multivariate analysis did not reveal any significant risk factors for 30-day stroke and death after surgery. Conclusion. The univariate analysis revealed the female sex, <70% ipsilateral carotid artery stenosis, and multiple brain lesions as significant risk factors of 30-day stroke and death after surgery. Further large-scale studies are needed to improve these findings.

Keywords: acute stroke, carotid stenosis, early carotid endarterectomy

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All articles of the authors: Bazhanov S.P., Khairutdinov A.I., Komarov R.N., Tarasov Yu.V., Valiullin D.Kh., Yakubov R.A., Yakubova V.T.

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