Saratov JOURNAL of Medical and Scientific Research

Development of neurosurgery for hemorrhagic stroke at the present stage (review)


Objective: analysis of trends in the development of neurosurgery for hemorrhagic stroke (HS) at the present stage. Research was carried out using the databases Web of Science, Scopus, PubMed, CyberLeninka, eLibrary by searching/analyzing sources published within 3 years, as well as individual publications older than 5 years (range from 2014 to 2022). The analysis of 50 literary sources was carried out. Neurosurgical approaches to the treatment of HS and current approaches to the study of pathological mechanisms, predictors and risk factors are considered. It is established that much attention is paid to the comparative study of the outcomes of classical and minimally invasive methods of pathology treatment. An increase in the proportion of the latter leads to a decrease in the mortality rate in HS. Arterial hypertension is an unambiguous risk factor in the development of pathology. Much research have been devoted to potential predictors of HS outcomes (prealbumin level, hyperuricemia, lymphocyte/neutrophil ratio). Special attention is paid to the mechanisms of formation of programmed cell deaths in the postoperative period. The list of molecular-cellular predictors optimal for risk stratification in HS has not been formed. It is necessary to search for therapeutic targets through an in-depth study of the mechanisms of development/remission of pathology at the molecular and cellular level.

1. Stakhovskaya LV, Kotova SV. Stroke. A guide for doctors. Moscow: MIA, 2014; p. 234-260.
2. Mustafin MS, Novikova LB, Akopyan АР, Shakirov RR. Neurosurgical aspects of hemorrhagic stroke. Annals of Clinical and Experimental Neurology 2018; (1): 19-23.
3. Donkor ES. Stroke in the 21st century: a snapshot of the burden, epidemiology, and quality of life. Stroke Res Treat 2018; (2018): 3238165.
4. Krylov VV, Dashyan VG, Godkov IM. Endoscopic surgery for hemorrhagic stroke. Moscow: Binom, 2014; 96 p.
5. Gaberel Т, Magheru С, Parienti JJ, et al. Intraventricular fibrinolysis versus external ventricular drainage alone in intraventricular hemorrhage: A meta-analysis. Stroke 2011; 42 (2): 2776-81.
6. Hanley DF, Lane K, McBee N, et al. Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial. Lancet (London, England) 2017; 389 (10069): 603-11.
7. Dey M, Jaffe J, Stadnik A, Awad IA. External ventricular drainage for intraventricular hemorrhage. Current Neurology and Neuroscience Reports 2012; 12 (1): 24-33.
8. Skvortsova VI, Shetova IM, Kakorina EP, et al. Reduction in stroke death rates through a package of measures to improve medical care for patients with vascular diseases in the Russian Federation. Profilakticheskaya Meditsina 2018; 21 (1): 4-10.
9. Rava RA, Seymour SE, LaQue ME, et al. Assessment of an artificial intelligence algorithm for detection of intracranial hemorrhage. World Neurosurgery 2021; (150): e209-17.
10. Trifan G, Arshi B, Testai FD. Intraventricular hemorrhage severity as a predictor of outcome in intracerebral hemorrhage. Front Neurol 2019; (10): 217.
11. Song L, Qiu, XM, Guo TT, et al. Association between anatomical location and hematoma expansion in deep intracerebral hemorrhage. Front Neurol 2022; (12): 749931.
12. Nguyen HS, Li L, Patel M, et al. Radiodensity of intraventricular hemorrhage associated with aneurysmal subarachnoid hemorrhage may be a negative predictor of outcome. Journal of Neurosurgery 2018; 128 (4): 1032-6.
13. Yarikov AV, Balyabin AV, Morev AV. Modern surgical methods for the treatment of hemorrhagic stroke. MediAl magazine 2016; 1 (18): 91-6.
14. Yarikov AV, Balyabin AV. Surgical treatment options for hemorrhagic stroke in the Nizhny Novgorod Neurosurgical Center. Medical Almanac 2015; 4 (39): 139-42.
15. Sidhartha JM, PurmaAR, Reddy LVPK, et al. Risk factors for medical complications of acute hemorrhagic stroke. Journal of Acute Disease 2015; 4 (3): 222-5.
16. Pinzon RT, Wijaya VO. Complications as poor prognostic factors in patients with hemorrhagic stroke: A hospital-based stroke registry. Int J Neurol Neurother 2020; (7): 96.
17. Yarikov AV, Balyabin AV. Recurrence of traumatic intracranial hematomas. Questions of Traumatology and Orthopedics 2014; 2 (9): 18-20.
18. Dashyan VG, Kryachev RYu, Shesterikov YaA, et al. Results of endoscopic and open removal of hypertensive subcortical hematomas. Russian Sklifosovsky Journal of Emergency Medical Care 2021; (1): 100-7.
19. Kobata Н, Ikeda N. Recent updates in neurosurgical interventions for spontaneous intracerebral hemorrhage: minimally invasive surgery to improve surgical performance. Front Neurol 2021; (12): 703189.
20. Chung DY, Mayer SA, Rordorf GA. External ventricular drains after subarachnoid hemorrhage: Is less more? Neurocritical Care 2018; 28 (2): 157-61.
21. Zhu J, Tang C, Cong Z, et al. Endoscopic intraventricular hematoma evacuation surgery versus external ventricular drainage for the treatment of patients with moderate to severe intraventricular hemorrhage: a multicenter, randomized, controlled trial. Trials 2020; 21 (1): 640.
22. Chugunova SA, Im EV, Sharina SF, et al. Results of introducing new methods of treating stroke in the regional vascular center of Yakutia over a ten-year period. Vestnik of North-Eastern Federal University. Series: Medical Sciences 2021; 1 (22): 76-85.
23. Hou D, Lu Y, Wu D, et al. Minimally invasive surgery in patients with intracerebral hemorrhage: A meta-analysis of randomized controlled trials. Front Neurol 2022; 12: 789757.
24. Broderick J, Grotta J, Naidech A, et al. The story of intracerebral hemorrhage: from recalcitrant to treatable disease. Stroke 2021; 52 (5): 1905-14.
25. Marenco-Hillembrand L, Suarez-Meade P, Ruiz Garcia H, et al. Minimally invasive surgery and transsulcal parafascicular approach in the evacuation of intracerebral haemorrhage. Stroke and Vascular Neurology 2019; 5 (1): 40-9.
26. Shao J, Witek A, Borghei-Razavi H, et al. Endoscopic evacuation of intracerebral hematoma utilizing a side-cutting aspiration device. Operative Neurosurgery (Hagerstown, Md.) 2020; 18(6): E248-54.
27. Katsuki M, Kakizawa Y, Nishikawa A, et al. Endoscopic hematoma removal of supratentorial intracerebral hemorrhage under local anesthesia reduces operative time compared to craniotomy. Sci Rep 2020; (10): 10389.
28. Kellner CP, Song R, AN M, et al. Time to evacuation and functional outcome after minimally invasive endoscopic intracerebral hemorrhage evacuation. Stroke 2021; 52 (9): e536-9.
29. Kellner CP, Schupper AJ, Mocco J. Surgical evacuation of intracerebral hemorrhage: the potential importance of timing. Stroke 2021; 52 (10): 3391-8.
30. Xu X, Zheng Y, Chen X, et al. Comparison of endoscopic evacuation, stereotactic aspiration and craniotomy for the treatment of supratentorial hypertensive intracerebral haemorrhage: study protocol for a randomised controlled trial. Trials 2017: (18): 296.
31. Fahmi A, Subianto H, Suroto N, et al. Stereotactic aspiration of spontaneous intracerebral hematoma: Case series. International Journal of Surgery Case Reports 2020; (72): 229-32.
32. Guo W, Liu H, Tan Z, et al. Comparison of endoscopic evacuation, stereotactic aspiration, and craniotomy for treatment of basal ganglia hemorrhage. J Neurointerv Surg 2020; (12): 55-61.
33. Liu H, Wu X, Tan Z, et al. Long-term effect of endoscopic evacuation for large basal ganglia hemorrhage with GCS scores § 8. Front Neurol 2020; (11): 848.
34. Dong H, Liu S, Jing L, et al. Hypertension among hemorrhagic stroke patients in northeast China: A population-based study 2017-2019. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research 2020; (26):e926581.
35. Karpova OV, Udalov YuD, Radionova DM. Stem hemorrhagic stroke: treatment approaches and opportunities for rehabilitation. Saratov Journal of Medical Scientific Research 2019; 15 (4): 986-9.
36. Hagg-Holmberg S, Dahlstrom EH, Forsblom CM, et al. The role of blood pressure in risk of ischemic and hemorrhagic stroke in type 1 diabetes. Cardiovascular Diabetology 2019; 18 (1):88.
37. Seung K, Ho W, Yeon K, et al. Blood pressure management in stroke patients. Journal of Neurocritical Care 2020; (13): 69-79.
38. Rist PM, Buring JE, Ridker PM, et al. Lipid levels and the risk of hemorrhagic stroke among women. Neurology 2019; 92 (19):e2286-94.
39. Fang Y, Gao S, Wang X, et al. Programmed cell deaths and potential crosstalk with blood-brain barrier dysfunction after hemorrhagic stroke. Frontiers in cellular neuroscience 2020: (14): 68.
40. Zhao H, Chen Y, Feng H. P2X7 receptor-associated programmed cell death in the pathophysiology of hemorrhagic stroke. Current Neuropharmacology 2018; 16 (9): 1282-95.
41. Song SY, Zhao XX, Rajah G, et al. Clinical significance of baseline neutrophil-to-lymphocyte ratio in patients with ischemic stroke or hemorrhagic stroke: an updated meta-analysis. Front Neurol 2019; (10): 1032.
42. Mapoure YN, Ayeah CM, Ba H, et al. The prognostic value of serum uric acid in the acute phase of hemorrhagic stroke patients in black Africans. The Pan African Medical Journal 2019; (32): 165.
43. Zhang SQ, Peng B, Stary CM, et al. Serum prealbumin as an effective prognostic indicator for determining clinical status and prognosis in patients with hemorrhagic stroke. Neural Regeneration Research 2017; 12 (7): 1097-1102.
44. de Oliveira MAL, Goffi A, Zampieri FG, et al. The critical care management of spontaneous intracranial hemorrhage: A contemporary review. Crit Care 2016; (20): 272.
45. Forti P, Maioli F, Zoli M. Association of early glycemic change with short-term mortality in lobar and non-lobar intracerebral hemorrhage. Sci Rep 2021; (11): 16059.
46. Al-Mufti F, Thabet AM, Singh T, et al. D: Clinical and radiographic predictors of intracerebral hemorrhage outcome. Intervent Neurol 2018; (7): 118-36.
47. McGurgan IJ, Ziai WC, Werring DJ, et al. Acute intracerebral haemorrhage: diagnosis and management. Practical Neurology 2021; (21): 128-36.
48. Sorogovets Al, Tsirkunova AG, Zubareva AD, Kurash IA. Application of minimally invasive surgery for hypertensive intracerebral hemorrhage. Young Scientist 2018; 46 (232): 92-4.
49. Scaggiante J, Zhang X, Mocco J, Kellner CP. Minimally invasive surgery for intracerebral hemorrhage. Stroke 2018; 49 (11): 2612-20.
50. de Oliveira Manoel AL. Surgery for spontaneous intracerebral hemorrhage. Crit Care 2020; (24): 45

2022_2_206-214.pdf1.05 MB

No votes yet