Parameters of local and integral mucociliary clearance in the postoperative period in patients with foreign bodies in the maxillary sinus
Heading: Otolaryngology Article type: Original article
Authors: Mareev O.V., Mareev G.O., Ermakov I.Yu., Fedosov I.V.
Organization: Saratov State Medical University, St. Petersburg State Hospital №40
Objective: to evaluate the local and integral parameters of the mucociliary clearance (MCC) of the nasal cavity in the postoperative period in patients with foreign bodies in the maxillary sinus using various methods of surgical approach to the maxillary sinus. Material and methods. The study performed in 90 patients with foreign bodies in the maxillary sinus and 60 healthy individuals. To evaluate MCC, we used the technique of high-speed digital video recording of the microscopic picture of the specimen and saccharin test; computed tomography (CT) data. Results. Local MCC in the rhinological healthy individuals in our study was 10.84±3.80 Hz. There is a linear correlation of the local MCC and the saccharin test with inverse mean strength (r=-0.64). Local MCC depend on the type of surgical approach; the saccharin test do not reflect the nature of the surgical injury and quickly normalized. The degree of pathological changes in the area of the ostiomeatal complex on the computed tomogram, correlates with the local MCC before and after surgery. Conclusion. The measured indicator of local MCC characterizes the processes in the area of the ostiomeatal complex and correlates with CT; the values of local MCC due to surgical trauma decrease for up to 3-5 months. The saccharin test is not a method for determining the osteomeatal complex function and cannot be used as a diagnostic criteria. The method of investigation of local MCC can be used as a criterion for choosing surgical access to the maxillary sinus.
Bibliography:
1. Zakharova GP, Yanov YuK, Shabalin VV. The mucociliary system of the upper respiratory tract. St. Petersburg: Dialog, 2010; 360 p.
2. Sedaghat МН, Shahmardan MM, Norouzi М, et al. Effect of cilia beat frequency on mucociliary clearance. J Biomed Phys Eng 2016; 6 (4): 265-78.
3. Magomedov MM, Zeinalova DF, Magomedova NM, et al. Functional state of the mucous membrane of the nasal cavity and paranasal sinuses after radical and minimally invasive surgical interventions. Bulletin of Otorhinolaryngology 2016; 81 (2): 88-92.
4. Myller JP, Luukkainen AT, Huhtala HS, et al. Satisfaction with maxillary sinus surgery might be influenced by risk factors. Allergy Rhinol (Providence) 2013; 4(1): e6-12. DOI: 10.2500/ar. 2013.4.0039.
5. Luukkainen A, Myller J, Torkkeli T, et al. Endoscopic sinus surgery with antrostomy has better early endoscopic recovery in comparison to the ostium-preserving technique. ISRN Otolaryngol2012; 2012: 189383. DOI: 10.5402/2012/189383.
6. Jiao J, Meng N, Wang H, et al. The effects of vitamins С and B12 on human nasal ciliary beat frequency. ВМС Compleent AlternMed2013; 13(1): 1-6. DOI: 10.1186/1472-6882-13-11.
7. Workman AD, Cohen NA. The effect of drugs and other compounds on the ciliary beat frequency of human respiratory epithelium. American Journal of Rhinology & Allergy 2014; 28 (6): 454-64. DOI:10.2500/ajra.2014.28.4092.
8. Chernykh NM. The mucociliary system with changes in the hormonal status. Russian Rhinology 2014; (4): 57-60.
9. Koskinen A, Salo R, Huhtala H, et al. Factors affecting revision rate of chronic rhinosinusitis. Laryngoscope Investig Otolaryngol2016; 1 (4): 96-105. DOI: 10.1002/lio2.27.
10. Venetis G, Bourlidou E, Liokatis PG, et al. Endoscopic assistance in the diagnosis and treatment of odontogenic maxillary sinus disease. Oral Maxillofac Surg 2014; 18 (2): 207-12. DOI: 10.1007/sl0006-013-0413-6.
11. Mareev OV, Mareev GO, Fedosov IV, et al. Evaluation of mucociliary clearance in the postoperative period after a maxillary sinus surgery. Science and Innovations in Medicine 2020; 5 (1): 23-7.
12. Piatti G, Scotti A, Ambrosetti U. Nasal ciliary beat after insertion of septo-valvular splints. Otolaryngol Head Neck Surg 2004; 130 (5): 558-62. DOI: 10.1016/j.otohns.2003.07.013.
13. Smith CM, Djakow J, Free RC, et al. CiliaFA: a research tool for automated, high-throughput measurement of ciliary beat frequency using freely available software. Cilia 2012; (1): 14. DOI: 10.1186/2046-2530-1-14.
14. Zhang L, Han DM, Wang H, et al. [Measurement of respiratory ciliary beat frequency quantified with high-speed
digital microscopy]. Zhonghua Er Bi Yan Hou Ke Za Zhi. 2004; 39 (7): 433-7. PMID: 15469118.
15. Boatsman JE, Calhoun KH, Ryan MW. Relationship between rhinosinusitis symptoms and mucociliary clearance time. Otolaryngol Head Neck Surg 2006; 134 (3): 491-3. DOI: 10.1016/j.otohns.2005.10.045.
16. Hosemann W, Gode U, Langer F, Wigand ME. Experimented Untersuchungen zur Wundheilung in den Nasenneben-hohlen. II. Spontaner Wundschluss und medikamentbse Effekte im standardisierten Wundmodell [Experimental studies of wound healing in the paranasal sinuses. II. Spontaneous wound healing and drug effects in a standardized wound model]. HNO 1991; 39 (2): 48-54.
17. Otori N, Fukami M, Yanagi K, et al. [Patency of the ostium of the frontal sinus after endoscopic endonasal surgery for chronic sinusitis]. Nihon Jibiinkoka Gakkai Kaiho 1996; 99 (5): 653-60. DOI: 10.3950/jibiinkoka.99.653. PMID: 8691302.
18. Huang HM, Cheng JJ, Liu CM, Lin KN. Mucosal healing and mucociliary transport change after endoscopic sinus surgery in children with chronic maxillary sinusitis. Int J Pediatr Otorhinolaryngol 2006; 70 (8): 1361-7. DOI: 10.1016/j.ijporl. 2006.01.016. PMID: 16519952.
Attachment | Size |
---|---|
2022_2_177-184.pdf | 464.98 KB |