Lysis of a thrombus-"rider" with massive pulmonary embolism after two weeks of treatment with Warfarin (clinical case)

Massive pulmonary embolism (PE) with damage to the trunk and main branches of the pulmonary artery is one of the most common causes of death in hospitalized patients, both surgical and therapeutic. At present, there are no clearly formulated recommendations on the duration of anticoagulant therapy for pulmonary embolism. In addition, there are no clear indications and timing of CT angiography in the clinical guidelines to monitor the presence of pulmonary artery thrombosis. The given clinical case clinical case demonstrates the lysis of a thrombus-"rider" spreading into the pulmonary arteries on both sides and further into the lobar, segmental and subsegmental branches after taking Warfarin for two weeks during hospital stay, followed by CT angiopulmonography before discharge.