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The effectiveness of the use of bioplastic materials based on chitosan in the local treatment of dermal burns

Year: 2021, volume 17 Issue: №4 Pages: 709-714
Heading: Surgery Article type: Original article
Authors: Griban P.A., Afanasov I.M., Usov V.V., Moguryan O.E., Sotnichenko S.A., Filatov Yu.N., Karakulev A.V., Bogdanova Yu.A., Shkuratov A.G., Bogdanov S.B.
Organization: Far Eastern Regional Medical Center of FMBA of Russia, Kuban State Medical University, Lomonosov Moscow State University, MIREA — Russian Technological University, Research Institute — Regional Clinical Hospital No. 1 n. a. Professors. V. Ochapovsky
Summary:

The aim was to evaluate the effectiveness of the use of bioplastic materials based on chitosan "ChitoPran" in the treatment of deep dermal burn wounds in comparison with atraumatic mesh dressings. 22 patients with deep dermal thermal burns were included in the study. Material and methods. In 2-3 days after injury surgical necrectomy of the affected areas to viable tissues was performed under general anesthesia. After surgical cleansing and local haemostasis using 1 % adrenaline solution, the wounds were covered with different materials: bioplastic material "ChitoPran" (main group, 12 patients) and atraumatic wound dressing "ParaPran" with chlorhexidine (comparison group, 10 people). Results. "ChitoPran" proved to be effective bioplastic wound dressing for the local treatment of burn wounds after necrectomy: it protects the newly formed epidermis, resorbs in 5.5±1.6 days and optimizes reparative processes, which allows in most cases to achieve epithelialization of deep dermal burns in 20.9±1.6 days without performing autologous skin transplantation. Conclusion. Epithelialization of deep dermal burns using "ChitoPran" is 3-4 days faster compared to the use of atraumatic mesh dressings.

Keywords: bioplastic material, wound covering

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All articles of the authors: Afanasov I.M., Bogdanov S.B. , Bogdanova Yu.A. , Filatov Yu.N., Griban P.A., Karakulev A. V. , Moguryan O.E., Shkuratov A.G., Sotnichenko S.A., Usov V.V.

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