Analysis of the AMO-ATOS-IKL efficiency in the treatment of primary open-angle glaucoma
Year: 2021, volume 17 Issue: №3 Pages: 669-675
Heading: Тhematic supplement Article type: Original article
Authors: Filatova V.S., Kamenskikh T.G., Veselova E.V.
Organization: Saratov State Medical University, University Clinical Hospital №2 (Clinic of Eye Diseases)
Heading: Тhematic supplement Article type: Original article
Authors: Filatova V.S., Kamenskikh T.G., Veselova E.V.
Organization: Saratov State Medical University, University Clinical Hospital №2 (Clinic of Eye Diseases)
Summary:
Purpose: increasing the effectiveness of therapy in patients with primary open-angle glaucoma (POAG) by developing combined magnetic and laser exposure. Material and Methods. 199 patients diagnosed with POAG I (n=66), II (n=68), III (n=65) stages were examined. Patients of the main group (n=103) underwent rotational laser magneto-stimulation in the projection of the eye drainage system using the AMO-ATOS-ICL treatment; control group patients (n=96) received local antihypertensive therapy. Ophthalmological examination, intraocular blood flow examination, electrophysiological examination were carried out; determined the level of monocytic chemoattractive protein (MCP-1), vasculoendothelial growth factor (VEGF) in blood serum. Results. Rotational laser magnetostimulation is most effective in the treatment of patients with early glaucoma changes, which is confirmed by the following indicators: increase in the amplitude of the P100 peak by 24.1 %; decrease in latency by 10.2%, p<0.001; an increase in the coefficient of ease of outflow by 13.3%; decrease in true intraocular pressure by 7.6%, p<0.001; increase in the minimum diastolic blood flow velocity by 9.7%, p=0.003; decrease in the resistance index in the posterior short ciliary arteries by 16.4%, p=0.001. Conclusion. The developed and tested in clinical practice technique of rotary laser magnetostimulation of the eye drainage system turned out to be effective in the immediate and long-term follow-up of patients.
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