Saratov JOURNAL of Medical and Scientific Research

Diagnostic capabilities of optical coherence tomography angiography in patients with primary open-angle glaucoma

Year: 2021, volume 17 Issue: №3 Pages: 662-665
Heading: Тhematic supplement Article type: Original article
Authors: Tikhonov D.A., Kamenskikh T.G., Kolbenev I.O., Veselova E.V.
Organization: Saratov State Medical University, University Clinical Hospital №2 (Clinic of Eye Diseases)
Summary:

Purpose: to assess the state of intraocular microcirculation in patients with primary open-angle glaucoma (POAG) before and after surgical treatment using optical coherence tomography angiography (Angio-OCT). Material and Methods. The study involved 30 patients (30 eyes) diagnosed with POAG stage lb (group 1) and 25 people (31 eyes) without ophthalmic pathology (group 2, control group). All patients with POAG underwent sinustrabeculectomy. Results. Patients with POAG revealed a decrease in the density of blood vessels (up to 18.10±0.53) and blood flow density of the optic nerve disc (up to 33.77±0.65). After surgical treatment, the vascular density increased to 19.06±0.32, the blood flow density to 37.74±0.32. After 6 months, the hemodynamic and morphofunctional parameters of the optic nerve disc head remained the same in comparison with the data obtained after the operation. Conclusion. After antiglaucoma operation, a significant increase in the hemodynamics of the optic nerve disc was observed, which lasted for 6 months and was accompanied by the stabilization of the morphofunctional indices of the optic nerve disc. The results of the optic nerve disc Angio-OCT can be used as an additional criterion for the stabilization of the glaucomatous process.

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