Application of rhythmic transcranial therapy with low-intensive magnetic field in the complex treatment of climacteric and postovarectomy syndromes

Objective is to assess the effectiveness of the inclusion of rhythmic transcranial stimulation (rTMS) in the treatment of climacteric (CS) and postovarectomy syndromes (POES). Material and Methods. 95 women with POES (main group IA(n=48), comparison IB (n=47)) and 135 women with CS (main IIA(n=68), comparison IIB (n=67)) were included. All patients underwent menopausal hormone therapy (MHT), in the main groups — in combination with rTMS. Results. The average age of patients with POES is 47.9±2.2, with CS — 53.6±3.5 years (p=0.042). The duration of menopause was 2.8±0.6 years. On the scales of physical and psychological components of health in the main groups IA, IIA showed higher values after 3, 6 months of therapy compared to the same parameters in the comparison groups IB, IIB. The dynamics of the decrease in the values of psychoemotional and neurovegetative disorders of the modified menopausal index in the main groups IA, MA after 3 months was more pronounced compared to the same parameters in the comparison groups IB, IIB. The ratio of the chances of normalization of the clinical picture by 6 months for the main group lAand comparison group IB is 2.5 with 95% Cl [1.05-6.16], and for the main group IIAand comparison group IIB — 7.6 with 95% Cl [3.05-19.05]. Conclusion. The inclusion in the treatment of CS and POES along with MGT rTMS improves the quality of life, improves immediate and long-term results.