Saratov JOURNAL of Medical and Scientific Research

Autonomic cardiac support in young males with arterial hypertension syndrome according to the type of hemodynamic response to physical exercise

Year: 2020, volume 16 Issue: №3 Pages: 728-736
Heading: Cardiology Article type: Original article
Authors: Zayats A.N., Shyshko V.I.
Organization: Grodno State Medical University

Objective: To evaluate the clinical and instrumental signs of autonomic dysfunction in young men with arterial hypertension (AH) syndrome depending on the type of hemodynamic response (TGR) to dosed physical activity. Material and Methods. Veloergometry (VEM) and cardiovascular testing (CVT) were performed in 208 men aged 18-29 years: 22 men in the control group, 34 men with physiological TGR, 52 men with hyperreactive TGR, 53 men with hypertensive TGR, 45 men with hyperdynamicTGO (HDTGR). Results: Clinical manifestation of autonomic dysfunction was present in less than 1/3 of patients regardless of TGR. In the HDTGR group SDNN was 36 (30; 54) ms, LF —605(363; 1073) ms2/Hz, HF — 322(160; 947) ms2/Hz and were significantly less than in other groups. According to the CVTdata, there was a paradoxical SDNN 1.2 times increase, the absence of HF and %VLF dynamics. Conclusion: Autonomic support is mostly disturbed in HDTGR, and is accompanied by a significant strain of the regulatory systems, hyporeactivity of the central regulatory mechanism and vagal unresponsiveness with a paradoxical SDNN increase.

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