Saratov JOURNAL of Medical and Scientific Research

Modern view on the problem of optic neuritis (systematic review)


The review discusses modern concepts of etiopathogenesis, clinic, diagnosis, treatment and preventive measures for optical neuritis, as well as the position of modern ophthalmology on the principles of management of patients with optical neuritis of various etiologies. The review includes 14 sources over the past 25 years from Russian (Elibrary CyberLeninka) and international (PubMed) databases.

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2. Gusev El, Zavalishin IA, Boiko AN. Multiple sclerosis, clinical guidelines. Moscow: Real Time, 2011; 528 p.
3. loyleva ЕЕ. Krivosheeva MS. Microperimetry in optic neuritis due to multiple sclerosis. Ophthalmosurgery 2016; (3): 33-8.
4. loyleva ЕЕ, Krivosheeva MS. Significance of assessment of neuroarchitectonics of the retina under optic neuritis. Practical Medicine 2018; 16 (4): 74-7.
5. loyleva Е, Krivosheeva М. Microperimetry in optic neuritis due to multiple sclerosis Neuro-Ophthalmology 2017; 41 (1):87-8.
6. Gabilondo I, Martinez-Lapsia EN, Martinez-Heras E, et al. Trans-synaptic axonal degeneration in the visual pathway in multiple sclerosis. Journal of Ophthalmology 2014; (23): 667-85.
7. Akopyan VS, Boyko AN, Davydovskaya MV, et al. Neuroarchitecture of the retina in multiple sclerosis: diagnostic capabilities of optical coherence tomography (preliminary results). Ophthalmology 2011; (1): 32-6.
8. loyleva ЕЕ, Krivosheeva MS, Smirnova MA. The results of examination of patients with optic neuritis in the debut of multiple sclerosis. Bulletin of the Orenburg State University 2014; (12): 143-46.
9. Keltner JL, Johnson СА, Spurr JO, et al. Visual field profile of optic neuritis: One-year follow-up in the Optic Neuritis Treatment Trial/The Optic Neuritis Study Group. Arch Ophthalmology 1994; (112): 946-53.
10. loyleva E, Krivosheeva M. Microperimetry in the diagnosis of the first manifestation of optic neuritis in multiple sclerosis. Journal of the Neurological Sciences 2015; (357): e47.
11. Zakharov AV, Poverennova IE, Khivintseva EV, et al. Analysis of the probability of transition of a monofocal clinically isolated syndrome to clinically significant multiple sclerosis. Saratov Journal of Medical Scientific Research 2012; 8 (2): 432-5.
12. Oberwahrenbrock Т, Ringelstein М, Jentschke S, et al. Retinal ganglion cell and inner plexiform layer thinning in clinically isolated syndrome. Mult Scler J 2013; (19): 1887-95.
13. Kuhle J, Disanto G. Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study. Mult Scler 2015 Feb 13. pii: 1352458514568827.
14. Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Annals of Neurology 2011; 69(2): 292-302.

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