Saratov JOURNAL of Medical and Scientific Research

2018, volume 14

Results of combined treatment of iris cysts

Year: 2018, volume 14 Issue: №4 Pages: 891-894
Heading: Ophtalmology Article type: Original article
Authors: Yarovoy А.А., Bulgakova E.S., Yarovaya V.A., Chochaeva A.M., Korobov E.N.
Organization: The S. Fyodorov Eye Microsurgery Federal State Institution
Summary:

Purpose. To present the own experience in iris cyst treatment. Materials and Methods. In this retrospective study 20 eyes with iris cysts were included. Lesions were managed with intracystic ethanol irrigation with and without subsequent surgical resection of the walls. Results. Complete iris cyst destruction was achieved in 16 cases. In 4 eyes cyst recurrence after ethanol irrigation was revealed and successfully treated by ethanol irrigation without subsequent surgical resection of the walls. No complications were seen within mean follow-up of 26 months. Conclusion. Intracystic ethanol irrigation is an effective treatment modality. Additional surgical resection of the cyst walls helps to improve treatment results with no signs of recurrences and complications.

Keywords: ethanol irrigation, iris cyst, surgical excision, treatment

Bilateral acute generalized uveitis with Vogt-Koyanagi-Harada Syndrome

Year: 2018, volume 14 Issue: №4 Pages: 886-891
Heading: Ophtalmology Article type: Case report
Authors: Latypova Е.А.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

This study presents a case of bilateral generalized uveitis with exudative retinal detachment and Vogt- Koyanagi-Harada syndrome with a severe fulminant course in 27 year-old man with underlying neurological manifestations and hearing loss. The delayed diagnosis of the disease led to the rapid development of the late stage of uveitis with depigmentation of the fundus in the form of the "setting sun", persistent reduction of vision and complications with development of cataract, ophthalmic hypertension, epiretinal synechia and relapses. High-dose corticosteroids and immunosuppressive therapy allowed to achieve a positive effect and partially restore visual functions. Uveitis with a symmetrical lesion in both eyes is often an ophthalmological manifestation of systemic diseases. When it develops in individuals with darker skin pigmentation it is necessary to bear in mind the Vogt- Koyanagi-Harad syndrome.

Keywords: bilateral uveitis, exudative retinal detachment, uveomeningoencephalitis, Vog-Koyanagi-Harad syndrom

Aggressive posterior retinopathy of prematurity in a child conceived by in vitro fertilization

Year: 2018, volume 14 Issue: №4 Pages: 882-885
Heading: Ophtalmology Article type: Case report
Authors: Latypova E.A., Somova A.B., Matryuk D.I., Abdrakhmanova Yu.A.
Organization: Bashkir State Medical University of the Russian Health Care, «Republican Children's Clinical Hospital», Ufa
Summary:

Aggressive posterior retinopathy of prematurity (AP-ROP) is the most severe form ofretinopathy of prematurity (RP), characterized by early onset, fulminant course with absence of stagingand resistance to treatment. Today, the increase in AP-ROPincidence is associated with the changing standards for nursingof severely premature infants and wideprevalence of assisted reproductive technology — in vitro fertilization (IVF). The article presents a clinical case of aggressiveposterior retinopathy of prematurity in a girl with agestational ageof 25 weeks and a birth weightof about 860 grams who was conceived by IVF. Medical and high-tech laser treatment, fullycarried out in time, has lead toregression of this disease, which mayallowto preserve and develop visual function.

Keywords: aggressive posterior retinopathy, fertilization in vitro (IVF), gestational age, retinal laser coagulation

Disruption of the microcirculation of the retinal macular zone in a patient who had hemorrhagic fever with renal syndrome according to OCT-angiography of the macula

Year: 2018, volume 14 Issue: №4 Pages: 880-882
Heading: Ophtalmology Article type: Case report
Authors: Aznabaev ВМ, Batyrshin RA, Aleksandrov АА, Idrisova LR, Khakimova NP.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

The article presents the results of a standard diagnostic examination and a description of the impaired microcirculation of the macular retinal area according to optical coherence tomography angiography (ОСТ angiography) in a patient who had hemorrhagic fever with renal syndrome. The survey revealed a violation of the microcirculation of the macula in the form of a decrease in perfusion of the inner layers of the retina. This diagnostic method allows objectively, quickly and without contact to assess the state of the microcirculation of the macula in persons who have had hemorrhagic fever with renal syndrome, and can be recommended for assessing the effects of the disease and preventing complications from the organ of vision.

Keywords: macula microcirculation, OCT-angiography

Results of treatment of optic neuritis

Year: 2018, volume 14 Issue: №4 Pages: 875-879
Heading: Ophtalmology Article type: Original article
Authors: Latypova Е.А.
Organization: Bashkir State Medical University of the Russian Health Care
Summary:

Purpose: to investigate the epidemiological and clinical features of optic neuritis, evaluate the effectiveness of treatment and underlying diseases. Material and Methods. 58 patients (60 eyes) with optic neuritis (ON) were observed. Among them, 54 adults (26 men, 28 women) aged 19-67 years (mean age 36±11.8 years) and 4 children (1 boy, 3 girls) 14-16 years. Along with the standard ophthalmologic examination, electrophysiological studies, visual evoked potentials and magnetic resonance imaging of the brain and orbit, and a consultation with a neurologist were conducted. The patients were divided into two groups. In the main group of 32 patients (34 eyes), the complex treatment is carried out according to the developed method, which includes daily administration of 1 % nicotinic acid solution in the age dose (from 1 ml to 6 ml per day) with pentoxifylline on the background of basic ON therapy. In the control group of 26 patients (26 eyes), along with basic therapy of 1% nicotinic acid, 1 ml intramuscularly is prescribed a course of 10-15 days. Results. The number of children of young working age (65.5%), including children (6.9%). In the overwhelming number of cases, intrabulbar neuritis was diagnosed (84.5%). In 8 of 9 patients, the precursor of retrobulbar neuritis (PN) was multiple sclerosis (MS). Among other etiological causes of ON viral infection prevailed (37.9%). In patients prolonged by the proposed method, an improvement in visual functions (increased visual acuity, expansion of the general boundaries of the visual field) was achieved in 91% of cases, including high vision (0.5-1.0) in 65% of cases; in patients of the control group, these indicators correspond to 54% and 23%. Conclusion. The use of nicotinic acid intravenously in age dosage with pentoxifyllone in complexes with basic therapy allows the use of methods of treatment of optical neuritis using etiology and can be recommended for widespread use in practical ophthalmology.

Keywords: nicotinic acid, optic neuritis, treatment

Central retinal vein thrombosis in a patient with newly diagnosed congenital thrombophilia

Year: 2018, volume 14 Issue: №4 Pages: 872-875
Heading: Ophtalmology Article type: Case report
Authors: Latypova E.A., Zagidullina A.Sh., Yamlikhanov A.G., Arslanova A.l., Nugmanova A.R.
Organization: Bashkir State Medical University of the Russian Health Care, City clinical hospital 10 Ufa
Summary:

To date the etiology and pathogenesis of retinal vein thrombosis have not been fully studied despite a large body of scientific research. The article describes a rare clinical case of central retinal vein thrombosis in a 52-year-old man with newly diagnosed congenital thrombophilia.

Keywords: congenital thrombophilia, folate cycle disorder, hyperhomocysteinemia, thrombosis

Surgical treatment of rhegmatogenous retinal detachment with inferior breaks using gas tamponade of the vitreal cavity

Year: 2018, volume 14 Issue: №4 Pages: 870-872
Heading: Ophtalmology Article type: Short message
Authors: Shkvorchenko D.O., Gorshkov I.M., Yukhananova A.V, Khurdaeva A.G.
Organization: The S. Fyodorov Eye Microsurgery Federal State Institution
Summary:

Purpose: to evaluate the efficacy of tamponade of a vitreous cavity with gas-air mixture in patients with rhegmatogenous retinal detachment (RRD) in the lower hemisphere. Materials and Methods. We examined and operated on 52 patients with RRD with the localization of the discontinuities in the lower hemisphere: 30 patients with RRD with involvement of macula and 22 patients with RRD without macular involvement. All patients underwent general and special ophthalmological examination. Standard surgical treatment of retinal detachment finalized with injection of gas-air mixture into the vitreal cavity was performed. Results. In all cases, patients with RRD without involvement of macula and in 27 cases of RRD with involvement of macula there was a full adherence of the retina. In 3 cases patients with RRD involving the macula underwent repeat surgery with tamponade of the vitreous cavity with silicone, after which the retina adherence was finally observed. Close relationship between the improvement of visual acuity in patients 6 months after the operation and reduction in retinal thickness. Conclusion. The obtained results demonstrate the possibility of using gas tamponade of the vitreous cavity in RRD surgery with localization of rupture in the lower hemisphere.

Keywords: perfluoropropane, regmatogenous retinal detachment, retinal tears

Surgical treatment of regmatogenous retinal detachment complicated by macular hole using platelet-rich blood plasma and local staining

Year: 2018, volume 14 Issue: №4 Pages: 867-870
Heading: Ophtalmology Article type: Original article
Authors: Zaharov V.D., Shkvorchenko D.O., Krupina E.A., Kakunina S.A., Norman K.S., Khurdaeva A.G., Yukhananova A.V.
Organization: The S. Fyodorov Eye Microsurgery Federal State Institution
Summary:

Purpose: to study the effectiveness of surgical treatment of regmatogenous retinal detachment (ROS) complicated by macular hole (MH) using platelet-rich blood plasma (PRP). Material and Methods. The study included 27 patients (27 eyes) with a diagnosis of ROS complicated by MH. In each case, the technique was used, namely, that after performing vitrectomy, a perfluororganic compound (PFOS) was injected into the hole area with a diameter of 2-3 diameter of the disk, to prevent penetration of dye under the retina, stained and removed internal limiting membrane (ILM). After serial PFOS/air replacement at the gap introduced PRP. The operation was completed with the introduction of silicone oil (CM). CM was removed from the vitreous cavity after 2 months. The follow-up period is 12 months. Results. In all cases, it was possible to achieve the adhesion of the retina and block Mr. During the observation period visual acuity increased to 0.1-0.9. Conclusion. According to the evaluation of the results, surgical treatment of regmatogenous retinal detachment complicated by MH using PRP is an effective method of treatment.

Keywords: internal limiting membrane, platelet-rich blood plasma, regmatogenous retinal detachment, vitrectomy, макулярный разрыв

Surgical treatment of regmatogenous retinal detachment complicated by macular hole using platelet-rich blood plasma and local staining

Year: 2018, volume 14 Issue: №4 Pages: 867-870
Heading: Ophtalmology Article type: Original article
Authors: Zaharov V.D., Shkvorchenko D.O., Krupina E.A., Kakunina S.A., Norman K.S., Khurdaeva A.G., Yukhananova A.V.
Organization: The S. Fyodorov Eye Microsurgery Federal State Institution
Summary:

Purpose: to study the effectiveness of surgical treatment of regmatogenous retinal detachment (ROS) complicated by macular hole (MH) using platelet-rich blood plasma (PRP). Material and Methods. The study included 27 patients (27 eyes) with a diagnosis of ROS complicated by MH. In each case, the technique was used, namely, that after performing vitrectomy, a perfluororganic compound (PFOS) was injected into the hole area with a diameter of 2-3 diameter of the disk, to prevent penetration of dye under the retina, stained and removed internal limiting membrane (ILM). After serial PFOS/air replacement at the gap introduced PRP. The operation was completed with the introduction of silicone oil (CM). CM was removed from the vitreous cavity after 2 months. The follow-up period is 12 months. Results. In all cases, it was possible to achieve the adhesion of the retina and block Mr. During the observation period visual acuity increased to 0.1-0.9. Conclusion. According to the evaluation of the results, surgical treatment of regmatogenous retinal detachment complicated by MH using PRP is an effective method of treatment.

Keywords: internal limiting membrane, platelet-rich blood plasma, regmatogenous retinal detachment, vitrectomy, макулярный разрыв

Evidence of the safe period intravitreal tamponade by perfluorodecalin in clinical practice

Year: 2018, volume 14 Issue: №4 Pages: 862-866
Heading: Ophtalmology Article type: Original article
Authors: Arslanov G.M., Aznabaev В.М., Mukhamadeev T.R., Dibaev T.I.
Organization: Saratov State Medical University, The Eye Clinic «Zrenie» (Saint Petersburg)
Summary:

 Purpose: to perform clinical testing of perfluorocarbon liquid on the basis of perfluorodecalin with the possibility of intravitreal postoperative tamponade in patients with vitreoretinal pathology and explain the effectiveness of this practice. Material and Methods. Were evaluated anatomical and clinical results of vitrectomy with PFCL intravitreal tamponade in 105 (113 eyes) patients with severe vitreoretinal pathology. Three observation groups were distinguished: group I (in-traoperative and postoperative intravitreal tamponade by perfluorodecalin, national sample); group II (only intraopera-tive use of perfluorodecalin, foreign sample); group III (only intraoperative use of perfluoro-1.3- dimethylcyclohexane). Results. Retinal attachment in the group of patients with postoperative intravitreal tamponade was 97.1% (visual acuity increased in 71.5% cases). All cases of failure or redetachment, postoperative complications and cataract progression did not have a statistically significant association with postoperative intravitreal tamponade as risk factor (x2=0,316; X2=0,068; x2=0.061; x2=0.403, p>0.05). Conclusion. Clinical testing of perfluorocarbon liquid intravitreal tamponade on the basis of perfluorodecalin in patients with vitreoretinal pathology showed high anatomical and clinical results with a high probability of retinal attachment.

Keywords: perfluorodecalin, PFCL