2016, volume 12

Цель; определить и сравнить концентрацию кальция и фосфора в интерстициальной жидкости тканей зачатка (пульпы, эмалевого органа) и фолликулярной жидкости по ходу центробежного перемещения. Материал и методы. Изучен состав интерстициальной жидкости пульпы, эмалевого органа и фолликулярной жидкости 23 зубных зачатков. Для биохимического анализа образцов использован ферментативно-фотоколориметрический метод на биохимическом полуавтоматическом анализаторе «Stat Fax 3300». Результаты. В интерстициальной жидкости пульпы концентрация кальция в 1,7 раза больше, чем в плазме, в 3 раза выше, чем в эмалевом органе, и в 7 раз больше, чем в фолликулярной жидкости. Средняя концентрация фосфора в пульпе в 10 раз выше, чем в плазме крови. Заключение. Выявлено весьма значимое различие концентраций остеотропных элементов в интерстициальных жидкостях изученных структур. Доказано, что концентрация кальция и фосфора убывает по ходу движения постулируемого потока жидкости от пульпы зачатка к перифолликулярному пространству. Повышение концентрации изученных элементов в интерстиции пульпы по сравнению с плазмой крови свидетельствует о способности пульпы концентрировать данные элементы и таким путем обеспечивать минерализацию обызвествленных тканей зуба и до его прорезывания.

The purpose is to consider the biomechanical modelling of cerebral arteries at different structural variants of intracranial arteries of vertebrobasilar system. Material and methods. By means of the system of the final and element analysis ANSYS on the basis of data on geometry, morphometricand biomechanical properties of cerebral arteries their biomechanical models have been constructed. On the received models for 9 structural variants of intracranial arteries of vertebrobasilar system, haemodynamic parameters and parameters of the intense deformed condition of walls of arteries have been analyzed. Results. The most frequent variant of a configuration of intracranial department of vertebrobasilar system is the combination of average in size of angles of connection of vertebrata and bifurcation of basilar arteries. Such option occurs in 49% of cases. More rare variant (1,5% of cases) with the narrow angles of connection of vertebrata and bifurcations of basilar arteries has been observed. The design of intracranial arteries of vertebrabasi-lar system exerts an impact on distribution of bloodflow and effective tension in a vascular wall of back brain arteries. Conclusion. According to the study it has been determined that the constructed individual biomechanical models may provide information on some parameters of haemodynamics and the intense deformed condition of a vascular wall which causes the development of atherosclerosis and intracranial aneurisms.

More than 70 literature sources are presented and analyzed in the work. Data sources are devoted to the connection between infection and development of atherosclerotic changes. It has been found out that the infection and the presence of pathogenic microorganisms influence the progression of atherosclerosis.

Objective: to determine the morphometrical variability of dental alveoli bilaterally, depending on their position in the alveolar part of the mandible. Material and Methods. The object of the study is to certify 70 cranions with mandibles of middle-aged adults (21-60 years) and 30 isolated mandibles without gender-and age-related characteristics. The objects of the study were taken from scientific cranial fundamental museum collection of the Department of Human Anatomy. For the scientific research Craniometry method was used according to generally accepted craniology process parameters. Dental alveoli on both sides of the mandible were studied. Results. It was established that longitudinal diameter prevails at tooth alveoli of a canine, the first and second premolars, cross diameter on the same side of a jaw at the left — at alveoli of a medial incisor and the first premolar in comparison with its right side. At dental alveoli the left-sided depth is larger of the first molar, of the second molar — the right-sided is larger. Longitudinally cross diameter in the direction from alveoli of front teeth to back ones increases at each subsequent alveolus, since the minimum size at incisors and reaching the maximum size at alveoli of the first and second molars. The largest depth of tooth alveoli is determined at a canine, the first and second premolars. Conclusion. Results of the research of bilateral and individual variability of parameters of tooth cells may be used in practical stomatology.

The aim of the study is to determine the influence of a partial temporary ischemia and reperfusion on the development of pancreatitis in laboratory rats. Material and Methods. The experiments were performed on 73 white rats. Occluded blood vessels and blood flow were recorded by digital biomicroscopy and laser speckle contrast imaging. Statistical data processing was carried out the program Statistica for Windows 6.0 using the Student's criterion. Results. Laser speckle imaging and digital microscopes provide the monitoring of blood flow in the vessels of the pancreas. After a five-minute partial ischemia reactive hyperemia occurs, changes are invertible. After a twenty-minute partial ischemic reactive hyperemia does not occur, without developing pancreatitis necrosis. Pancreas of alcoholized rats has been found out to be more sensitive to ischemia. Conclusion. The method of laser speckle imaging and intravital microscopy after digital five- and twenty-minute partial ischemia of the pancreas revealed phase opposite directed changes in its tissue perfusion and varying severity of postischemic pancreatitis.

Problems of social conditionality of population health are a traditional topic to discuss both in medical and social sciences. Availability of health care is considered from the perspective of social factors of macro level, representing the widest context of social factors to health risk. In Russia, the increasing availability of health care for the population is considered as a priority of social policy. The authors of the review publications consider the trends of accessibility of medical care to the population of contemporary Russia. It is noted in the article that currently the availability and quality of medical care, pretentiousness of state assurances for free medical care, and their imbalance with available financial resources are considered as one of the major Russian health care problems.

The article presents biography of Professor LA Varshamov, his scientific and practical contribution to the development of Russian Medicine and to the training of academic staff at the Saratov Medical Institute.

The article is concerned with the communication skills of higher school teachers and significant aspects of theory and practice of pedagogical discourse.

The article explains the prospects of sociological interpretation of the phenomenon of compliance. The theoretical construct of the phenomenon of compliance is based on the allocation of social parameters of the therapeutic interaction as a particular social practice. The presence of the disease is seen as a sign of social, determined by the dynamics of social activity of the patient in the context of changes in the characteristics of social interaction. The author gives a sociological interpretation of the concept of compliance as the dynamic state of the area of therapeutic interaction. Substantiates the prospects of sociological reflection of compliance, which allows to carry out the social dimension of the conditions of stability/instability of the therapeutic interaction, predict and manage change behavioral strategies patients.

Adherence to treatment is an important factor in diabetes management. Poor adherence may cause ineffective control, especially in insulin-treated patients. Aim of the study: to evaluate the adherence to nutrition, physical activity and self-monitoring in T2DM patients who do and do not receive insulin treatment. Materials and methods. 550 T2DM patients were examined as a part of mobile diabetes center in different areas of the Nizhny Novgorod region. Clinical examination results, HbA1c, creatinine and microalbuminuria were assessed. Adherence to treatment was evaluated by questionnaire Diabetes Self-Care Activities. Results. Insulin-treated patients had longer diabetes duration and worse HbA1 с level and similar levels of adherence related to diet, physical activity, foot care. Only for glucose self-monitoring was adherence higher. Best HbA1c values were observed in patients with adherence in middle region of 3-5 days. Conclusion. Long diabetes duration and worse glycemic control in insulin-treated T2DM patients is not associated with better adherence to treatment. This may be viewed as evidence on insufficient patients education and can be a potential target for improvement of glycemic control.