№3, 2016, volume 12

Objective: to determine the risk of thromboembolic complications in orthopaedic patients. Material and methods. A survey of 151 patients who had undergone total endoprosthesis of large joints of the lower extremities, aged 25-68, under treatment in Saratov Scientific Research Institute of Orthopedics and Traumatology. Results. The performed research allowed to establish that at values of the content of VEGF-A to 183,6 PG/ml a low risk of thromboembolic complications was predicted and for values above 183,6 PG/ml high risk was prognosed. Conclusion. We have proved high efficiency of using the relationship of VEGF and PAI-1 in serum, which plays a leading role in the development of predisposition to thrombosis.

Objective: to determine the risk of thromboembolic complications in orthopaedic patients. Material and methods. A survey of 151 patients who had undergone total endoprosthesis of large joints of the lower extremities, aged 25-68, under treatment in Saratov Scientific Research Institute of Orthopedics and Traumatology. Results. The performed research allowed to establish that at values of the content of VEGF-A to 183,6 PG/ml a low risk of thromboembolic complications was predicted and for values above 183,6 PG/ml high risk was prognosed. Conclusion. We have proved high efficiency of using the relationship of VEGF and PAI-1 in serum, which plays a leading role in the development of predisposition to thrombosis.

The combination of heart failure, obstructive sleep apnea syndrome and atrial fibrillation is a widespread case. Besides, the correlation between these pathologies has not been accurately determined yet. The aim of the research is to determine the specific features of heart failure in patients with atrial fibrillation. Material and Methods. 174 patients were involved in the research. There were people at the age of 75 and younger suffering with heart failure. 116 of them also experienced artrial fibrillation and 58 sinus rhythm. In addition, all the patients involved had hypertension. The patients underwent echocardiography and respiratory monitoring. Results. Statistical analysis showed that atrial fibrillation was a more powerful predictor of the occurrence of obstructive sleep apnea than heart failure. Furthermore, we have found significant peculiarities in relations between the features of heart failure, presence and severity of obstructive sleep apnea in the group of the patients with atrial fibrillation. Remodeling of the left heart cameras was more typical for the patients with atrial fibrillation. Conclusion. Heart failure has significant features in patients with atrial fibrillation and obstructive sleep apnea.

Objective: to study the individually-typological features of the person of young men with prehypertension. Material and Methods. With the help of complex tests: Reduced Multiple Personality Questionnaire for research (MMPI), the Heck — Hess, Spielberger — Hanin, Index lifestyle were examined 95 healthy young men with different levels of blood pressure: optimal, normal and high normal. Results. It has been shown that people with normal and high normal blood pressure have different individually-typological features of the person and, based on this criterion can not be combined into a single group prehypertension. Men with normal blood pressure values on the studied parameters were similar to individuals with optimal blood pressure value. Persons with high normal level of blood pressure had a psychosomatic predisposition personality profile MMPI, with its fixation on physical sensations, with the increase of anxiety, neuroticism and the overall intensity of psychological protection. Conclusion. It is advisable to carry out a personalized approach to the psychological correction of identified changes in primary prevention of arterial hypertension in young men.

Objective: to prove the role of office hysteroscopy as an important additional method in diagnostics of puberty abnormal uterine bleeding (AUB). Material and methods. The study involved 68 patients with AUB. The average age was 13.4 years (10-17 years). The main complaint of patients concerned bleeding from genital tract during 10-45 days (on an average 28.4 days). Patients were divided into 3 groups according to the type of AUB determined based on the level of serum estradiol, physical and sexual development, internal genitalia ultrasound data: 35 hypo estrogenic girls, 24 girls with normal estrogenic and 9 girls with hyper estrogenic type of AUB. All of the girls took the office hysteroscopy. Results. When performing hysteroscopy it was revealed that there were a clear relationship between the degree of estrogenic saturation and visual picture obtained in the course of the study. Conclusion. Hysteroscopy enables maximum visualization of uterine cavity, which allows to verify the diagnosis, to reduce the "over diagnosis" rate of organic pathology, perform a differentiated approach to treatment of diseases, based on determination of estradiol level in serum and data obtained in the study.

Objective: estimation of safety of most popular snacks and flour pastry products with the extended expiration date and considerable maintenance of fat in studies in animals. Material and Methods. Influences of snacks products with different maintenance of toxic foods of oxidization and copolymerizing of insoluble in petroleum ether fat components on the organism of animals at the protracted consumption by the haematological and histological methods of research were studied. Results. It was determined that the high concentrations of fat components of copolymerizing and oxidization of some types of snacks and flour pastry wares with the protracted expiration date possessed the toxic operating on the organism of laboratory animals and caused the expressed changes in the morphological and biochemical composition of the blood test, and also pathological processes in the tissue and cells. Conclusion. The analysis of results of undertaken studies proved the necessity of the sanitary-technological provision of safety of products with the extended expiration date and considerable maintenance of foods with oxidization of fat components.

Objective: assessment of the impact factors of teaching and working environment in the functional state of an organism of students mastering specialty of workers on river and rail transport. Material and Methods. As a part of natural hygienic experiment the study of the organization and conditions of theoretical and industrial training of adolescents, as well as the monitoring control indicators of their health status has been conducted for two and a half years of training among 120 students. Results. Modern hygienic characteristics of conditions and characteristics of teaching and the production process during the development of adolescent boys working skills on the river and rail transport have been presented. The priority factors influencing the functional state of an organism of students of professional schools have been established. Conclusion. Analysis of the research results has showed that the most pronounced changes in the functional body status of adolescent boys were observed during the development of educational and industrial practice.

Aim: to detect the regularities of age variability of bones in the forearm at adult men. Material and Methods. By the method of a direct osteometry the greatest length and the circle of the middle diaphysis of radial and ulnar bones were determined. The thickness-length index reflecting massiveness of a bone was defined as a percentage of a circle of middle diaphysis to the greatest length of a bone. Results. Age features of the greatest length, the greatest circle of a diaphysis and the thickness-length index of bones in the forearm, and also correlation of the studied parameters with a body length were revealed. Conclusion. The greatest length of radial and ulnar bones changes with age slightly whereas the circle of the middle diaphysis of bones in the forearm significantly increases with age according to the statistics that affects the increase in an index of massiveness of bones.