№3, 2012, volume 8

Analysis of literature review has presented authors' opinion about regularities of consistent change of haemopoietic cell differentiation steps in bone marrow. Particular attention has been paid to the role of numerous cytokines (stem cell factor, fit-3ligand, interleukine-3, interleukine-4, interleukine-6, interleukine-7, tumor necrosis factor, colony stimulating factors, erythropoietin, thrombopoietin) in mechanisms of myelo-, erythro- and thrombocytopoiesis in the normal conditions. Results of investigation have showed the important significance of blood cytokine profile disturbances in pathogenesis of tumor progression in chronic lymphocytic leukaemia.

The article presents the literature review analysis focusing on the problems concerned with hospitals state resources supply. The characteristics of purchase management in the modern socio-economic conditions are highlighted.

This review is devoted to a comparative analysis of receptor status, immunity, angiogenesis, metastatic mammal glands cancer expression profiling in humans and animals. Angiogenesis has been assessed by quantitative and immunohistochemical characteristics by means of evaluation of microvascular density (MVD) using Claudin-5 (CLDN-5) as a marker of vascular endothelium in tumors of mammary glands in dogs.

The article dwells on the research of units of interactive social management in healthcare service. It stresses the following: the necessity of making healthcare service more informative, strengthening of government position and creating of information community in the sphere of healthcare service. The article also observes the use of innovative management technologies and the way they influence personnel efficiency.

Purpose: to detect variability of absolute and relative sizes of shin bones. Materials and methods. Parameters of large and small tibial bones (n=208) of adults aged from 22 to 89 years (118 men and 90 women) have been studied. Osteo- and anthropometry methods have been applied. Results. Sexual dimorphism, age variability and bilateral dissymmetry of morphometric parameters of shin bones compared with anthropometrical parameters have been studied. Conclusion. Absolute and relative parameters of shin bones have been determined by the type of constitution.

The research work presents modern questions of Peyer's plaques on macro- and microscopical levels. Structures responsible for local immunity of digestive system have been described.

The purpose: to reveal laws of parameters variability of cross-section changeability and cross-section-outgrowth part of a vertebral artery in aspects of age variability, sexual dimorphism and a bilateral dissymmetry. Material and methods. Investigated cross-section cuts of vertebral segments with contents ofvertebral channel and channel of a vertebral artery (n=90); Kt- and MRT-grams (n=146), cervical vertebrae (n=742) complete sets with a known sex and age. The area of cross-section section was defined. Results. Age-sexual features and a bilateral dissymmetry of the area of cross-section section of a vertebral artery and cross-section apertures of cervical vertebras are revealed. Conclusion. The transverse section foramen ofvertebral arteries gradually increases with the years, apparently, at the expense of a thickening of a wall of an artery as a result of atherosclerotic damage whereas the area of section of cross-section apertures at first increases to definitive sizes, and then decreases, probably, owing to the hyperostosis phenomena. The given parameters possess sexual dimorphism and bilateral dissymmetry.