Saratov JOURNAL of Medical and Scientific Research

PUVA-bath photochemotherapy in the treatment of psoriasis

Year: 2012, volume 8 Issue: №2 Pages: 639-643
Heading: Skin Diseases Article type: Original article
Authors: Reznikova M.A., Slesarenko N.A., Utz S.R.
Organization: Saratov State Medical University

Aims. The study aimed to evaluate the effcacy of PUVA-bath photochemotherapy in the treatment of the severe psoriasis. Materials and methods. Twenty six patients aged from 18 to 56 were examined. All patients suffer from psoriasis vulgaris and exudativa. The two groups were comparable in terms of age, gender, duration of the disease. We used psoriasis area and severity index (PASI) before and after the treatment. All the patients received PUVA bath therapy (aqueous solution of 1 mg ammifurin l). Results. Clinical remission and marked improvement of clinical condition (a 76 % and more fall in the PASI index) were achieved in 80,9 % in both groups in average. No systemic adverse effects inherent in photosensitizing drug tablets were recorded in the course of PUVA-bath therapy. Conclusion. Effciency and safety of this method were demonstrated. The duration and summary dosage of UVA depends on clinical form.

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