№1, 2012, volume 8
Cytoprotective effect of cytoflavinum at treatment of thermal injury of various severity level
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Bozhedomov A.J., Morrison V.V., Shulaeva N.M., Nikitina V.V., Ivanenko I.L.
Organization: Saratov State Medical University, Saratov City Clinical Hospital №7
The purpose of research was studying of cytoprotective effect of cytoflavinum at a thermal trauma of different severity level. Materials and methods. 169 patients with thermal burns with a favorable outcome and gravity of a thermal trauma from 30 to 170 points on Franc were under research. 28 patients took standard dosage of cytoflavinum while complex therapy. Results. Patients with thermal trauma more than 60 points on Franc took Cytoflavinumuse and demonstrated decrease in intensity of system inflammatory response syndrome (SIRS), reduction of band neutrophils portion, lowering of erythrocyte number, smaller activation ofthrombocytopoiesis, dicrease of concentration of vascular endothelial growth factor. Positive effect was not revealed in group of patients with thermal trauma less than 60 points who received cytoflavinum. Conclusion. Use of cytoflavinum was the most effective at thermal trauma gravity more than 60 points on Franc
Adverse drug reactions in self-medication
Heading: Clinical Pharmacology Article type: Original article
Authors: Smuseva O.N., Solovkina Yu.V.
Organization: Volgograd State Medical University
The research goal is to study the actual problem of self-medication. The Association of the European Self-Medication Industry (AESGP) considers the term «responsible self-medication». The key characteristic is that the patients are responsible for their health. The article presents cases of self-medication thoroughly analyzed in Volgograd Regional Centre of Drug Safety Monitoring. Some of them may be considered as unfavourable and even lethal. Therefore it should be mentioned that there is one more benefit of rational pharmacotherapy with priority of prescriptions made by doctors. Medical professionals can estimate potential pharmacological risk with individual pharmacokinetic and phar-macodynamic features, allergic anamnesis and carry out monitoring of pharmacotherapy
Structural disproportions in regional medical standards in treatment of blood circulatory disorders
Heading: Health Service Organization Article type: Original article
Authors: Sazanova G.Yu.
Organization: Saratov State Medical University
The research goal is to consider the opinion of physicians about the financial medical assistance standards to patients with blood circulatory disorders. Materials and methods: 530 doctors of different specialties were interviewed. Some sociological and statistical methods were used in the study. Results: The majority of respondents (83%) considered that it was necessary to coordinate financial support of diagnostic and treatment expenditures with the standards of the regional program of rendering free medical aid to patients with blood circulatory disorders. Conclusion: The issue of medical standards fully depends on the staff organization and medicamentous provision
Medical service at institutions of various forms of ownership
Heading: Health Service Organization Article type: Original article
Authors: Mikhalchenko D.V., Firsova I.V.
Organization: Volgograd State Medical University
Objective: To analyze the consumption of medical service in institutions of various forms of ownership on the example of the Volgograd region. Materials and methods: To study a culture of consumption of medical service used data from a survey of patients of private and public medical institutions during the one-dimensional stratified sampling. The study used the method of comparative analysis. Results. Data have been obtained by questionnaire survey. Conclusion: the need to develop recommendations to optimize state and private partnership in medicine
Social Status Dynamics of Raising Professional Skills System of Paramedical Personnel (interview materials)
Heading: Health Service Organization Article type: Author's opinion
Authors: Andriyanova Е.А., Aleshkina О. Yu., Porokh L.I.
Organization: Volgograd Oncological Dispensary № 2, Saratov State Medical University
The results of sociological research (interview) are presented in the work. Factors of social status dynamics of raising skills system for paramedical personnel in the Soviet and post-Soviet periods have been revealed and studied
Characteristics of Clinico-pathologic Presentations of Chronic Gastroduodenitis in Children with Lambliasis Invasion
Heading: Macro- and Micromorphology Article type: Original article
Authors: Matveeva O.V., Maslyakova G.N., Zhandarova L.F., Popova I.Yu., Neklyudov Yu.A., Alekseev Yu.D.
Organization: Saratov State Medical University
The analysis of anamnestic and clinical indices, and also morphological investigation of biopsy materials of mucous coat of stomach and duodenum in children with chronic gastroduodenitis of different etiology including lambliasis invasion is carried out with the purpose of detecting features of clinicopathologic presentations of chronic gastroduodenitis in children with and without lambliasis invasion. Material and methods. 100 patients (50 children with confirmed lambliasis invasion and 50 patients without lambliasis invasion) aged from 2 up to 16 were under observation. The material for histologic study was received as a result of fibrogastroduodenoscopy carried out with target biopsy of fundic, antrum and duodenum mucosa. Results. As a result of the findings moderate pains sited in epigastric and periumbilical regions are characteristic for children with lambliasis invasion; irradiation and cramping characteristics of pains are typical. Conclusion. Manifestation of pains is not connected with the time of day and food intake, manifestation of seasonal prevalence is not typical as well, and progression of inflammatory process in the mucous coat of the stomach and duodenum is declared itself as a diffuse gastritis of the fundic part, a diffuse gastritis of the antral part, subatrophic duodenitis with cyst formation of Brunner's glands, and also the presence of eosinophilic leucocytes in the cellular infiltrate
Comparative analysis of morphogeometric parameters of forward cranial pole depending on type of a skull basis
Heading: Macro- and Micromorphology Article type: Original article
Authors: Aleshkina О.Yu., Hurchak Yu.A., Rossoshansky D.N., Anisimov A.N.
Organization: Saratov State Medical University
The purpose of the work is comparison of parameters of a forward cranial pole depending on type of a skull basis. The research material contained 100 adult skulls divided into three craniotypes. The method of craniotopometry was used for measuring the parameters and further calculation of average value and their comparison among themselves. Results. The research helped to reveal that length of a forward cranial pole, length of a lateral part on the right and at the left, a corner f.c.-s-n prevail at flexibasilar craniotype. Conclusions. The width of a forward cranial pole, width of a lateral part on the right and at the left, a corner f.c.-n-g are more at platibasilar craniotype
Morphological and biomechanical structural characteristics of medial cerebral artery in adults
Heading: Macro- and Micromorphology Article type: Original article
Authors: Nikolenko V.N., Fomkina О.A., Nekljudov Ju.A., Alekseev Ju.D.
Organization: Saratov State Medical University
The research goal is to study general strength, breaking point, Young's modulus (tensile modulus), absolute and relative strain of medial cerebral artery. Materials end methods. External diameter of medial cerebral artery, thickness of its wall and diameter of a lumen have been measured under the microscope on cross-section edges. In total 200 arteries (144 — from corpses of men, 56 — from corpses of women) received not later than 16 hours after autopsy of adults have been investigated. Results. Lethal cases resulted from acute or chronic vascular cerebral pathology have not been included in the study. Authentic predominance of wall thickness (14,8%), lumen diameter (50,3%) and general wall strength (13,8%) has been revealed statistically in men. Bilateral differences of parameters have been expressed by 1,0% (external diameter and wall thickness of an artery) to 10,0% (Young's modulus) and have been determined as statistically insignificant (p>0,05). Age aspect has shown intensity of morphological characteristics of medial cerebral artery. In conclusion it is worth while noting that after the age of 35 wall strength and resistance to strain of medial cerebral artery are authentically diminished; the artery becomes less rigid. Capability to elongation remains constant but after the age of 75 it decreases
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