Saratov JOURNAL of Medical and Scientific Research

№3, 2009, volume 5

Academic V.I. Skvortsov (Dedicated to the 130-th Anniversary of His Birth)

Year: 2009, volume 5 Issue: №3 Pages: 464-467
Heading: History of Medicine. Anniversary Dates Article type:
Authors: А.А. Svistunov A.I. Zavyalov
Organization: Saratov State Medical University

In the article are presented biographic data about professor V. I. Skvortsove, reflecting his scientific and practical contribution to the development of domestic pharmacology and toxicology, and to the organization of opening of the higher female medical education in Saratov

Keywords: professor V.I. Skvortsov, pharmacology, biography

Kulchitsky's Casus: Materials To The Biography Of Professor N.K. Kulchitsky

Year: 2009, volume 5 Issue: №3 Pages: 454-463
Heading: History of Medicine. Anniversary Dates Article type: Review
Authors: В.В. Голубинов
Organization: RF Designers' Union

In 2009 in two foreign medical editions the detailed biography of professor N.K.Kulchitsky (1856 — 1925) has been first published. N.K.Kulchitsky, the world famous Russian scientist, histologist, professor, Senator and the last Minister of education of Imperial Russia, in 1912-1914 was the director of Kazan educational district to which Saratov University also belonged at that time. V.V. Golubinov — one of the publications authors, the great-grandson of N.K.Kulchitsky, graduate of Saratov University n.a. N.G.Chernyshevsky, psychologist and designer-schedule is the author of the emblem of Saratov Medical University which decorates our journal's cover narrates about his great-grandfather

Keywords: «Kulchitsky (enterochromaffin) cells, the revolution of 1917, Russian emigration, professor N.K.Kulchitsky's biography, history of medicine, histology, central nervous system

V.V. Maslovskiy — The Father Of Medical Dynasty

Year: 2009, volume 5 Issue: №3 Pages: 450-454
Heading: History of Medicine. Anniversary Dates Article type:
Authors: L.D. Sidorova
Organization: Saratov State Medical University

Biographic data about professor V.V. Maslovskiy that reflect his scientific and practical contribution to the development of nativ morphology have been presented in the article

Keywords: Professor V.V. Maslovskiy, department of human anatomy

Introduction Of Educational And Methodic Complex Into Pedagogical Process At Pediatric Department

Year: 2009, volume 5 Issue: №3 Pages: 447-449
Heading: Pedagogics and Education Article type: Short message
Authors: А.А. Svistunov, V.I. Goremykin, A.A. Protopopov, I.V. Koroleva, I.A. Egorova, S.Yu. Elizarova, L.N. Volkova
Organization: Saratov State Medical University

2008 academic year is marked by the introduction of educational and methodological complex into the academic process at Saratov State Medical University. The first experience of its functionality at pediatric faculty is characterized in the article. It contributes to improving of educational process, methodological and informational systems, coordination of the process of teaching. It promotes the further development of extra curriculum work of staff and control of the quality of students' training

Keywords: educational and methodological complex, quality of education

Systemic Lupus Erythromatosis or Hiv Infection «Mask»?

Year: 2009, volume 5 Issue: №3 Pages: 444-446
Heading: Practice physician Article type: Short message
Authors: Е.Н. Скрябина, Н.А. Магдеева, И.Ф. Нам
Organization: Saratov State Medical University, Saratov Regional Clinical Hospital

The difficulties while conducting the differential diagnosis between systemic lupus erythromatosis (SLE) and HIV infection due to their clinical resemblance are reflected in this article

Keywords: systemic lupus erythromatosis, HIV infection, differential diagnosis

Technique Preventive Maintenance of Complications at Damages of the Pancreas

Year: 2009, volume 5 Issue: №3 Pages: 440-443
Heading: Surgery Article type: Original article
Authors: M.S. Gromov, D.A. Alexandrov, A.M. Skorokhod, S.V. Capralov, I.A. Samedov, V.S. Tarasenco
Organization: Saratov Military Medical Institute

Results of treatment of 135 victims with damage of a pancreas and results of experimental researches lead on 127 white rats are analysed. It is established, that expansion of volume of operation on damaged iron does not conduct to
improvement of results of treatment. Phase changes of average perfusion blood in a pancreas are revealed at development of an experimental posttraumatic pancreatitis. Development destruction in iron coincided on time with a phase re-perfusion. Local hypothermya pancreas reduced rate re-perfusion and reduced a degree destruction its fabrics. By results of research the technique intraoperation preventive maintenance of complications of damages of a pancreas is developed

Keywords: average perfusion, laser Doppler floumetry, local hypothermya, pancreatitis, posttraumatic pancreatitis

Thrombocyte Aggregation Activity at Patient with Acute Pancreatitis

Year: 2009, volume 5 Issue: №3 Pages: 438-440
Heading: Surgery Article type: Original article
Authors: B.B. Bromberg, V.F. Kirichuk, A.A. Svirin
Organization: Saratov Military Medical Institute, Saratov State Medical University

The study of the thrombocyte aggregation activity parameters has been carried out in 126 patient undergoing treatment having the diagnosis of acute pancreatitis 67(53,2%) of all patient showed non-aggravated course of acute pancreatitis, the severe coure was in 59(46,8%) of patients. The enhanced thrombocyte aggregation activity has been estimated not to depend on the severity of the disease development. In returns completely to norm to the 15 day of treatment in non-aggravated course and partially in aggravated coure of disease understudy

Keywords: acute pancreatitis, thrombocyte aggregation activity

Clinical And Morphological Androgenic Status Characteristics At Children Suffering From Hypospadias And Its Influence On Results Of Surgical Correction

Year: 2009, volume 5 Issue: №3 Pages: 433-437
Heading: Urology Article type: Original article
Authors: D.A. Zharkov, N.Ju. Raigorodskaya, F.K. Napolnikov, E.N. Tsmokalyuk
Organization: Saratov Clinical Hospital №3, Saratov State Medical University

The goal of this article is to estimate the androgenic status and analyze its influence on the surgical treatment of hypospadias. From 2000 till 2008 there were 209 children under treatment, whose age varied from 8 months till 15 years old (average age — 4,5+ 1,5). 49 patients were subjected to clinical, humoral and morphological study. Preoperational preparation was carried out by testosterone medications. The comparison group consisted of 10 boys with cicatricial phimosis.
The patients with the medium and back forms of hypospadias suffered from the androgenic deficit characterized by proximal level of meatus ectopia, diminution of penis length and prostate volume, decrease of blood vessels in deep layers of penis skin. The testosterone pre-operational medication of patients makes possible to improve the results of surgical correction due to blood supply of plastic material. On the basis of recieved data logistically regressive model has been worked out and the prognosis of results has been estimated

Keywords: children, surgical treatment of hypospadias

Profibrotic Mediators In Assessment Of Tubulointerstitial Changes In Surgical Treatment Of Patients With Urolithiasis

Year: 2009, volume 5 Issue: №3 Pages: 428-433
Heading: Urology Article type: Original article
Authors: P.V. Glybochko, A.N. Rossolovskiy, A.N. Ponukalin, N.B. Zakharova, G.N. Maslyakova, A.M. Napsheva
Organization: Saratov State Medical University

The aim of present work has been an assessment of degree of tubulointerstitial modifications of kidney parenchyma in patients with urolithiasis in different stages of surgical treatment using non-invasive mediators of nephrofibrosis and angiogenesis. The results of operations of 65 patients have been analysed. The content of nephrofibrosis molecular mediators in blood serum and urine has been determined. It has been shown that the most informative non-invasive mediators of tubulointerstitial fibrosis are IL12, VEGF in blood serum and b2-microglobulins MG, MCP 1 and NO excreted with urine. Patients with bilateral urolithiasis accompanied by expressive tubulointerstitial damages have had high indices of nephrofibrosis in postoperative period that can indicate irreversibility of these changes, leading to progression of chronic kidney disease

Keywords: urolithiasis, tubulointerstitial damages, mediators of nephrofibrosis

Pathogenetic Aspects of Treatment of a Chronic Cystitis

Year: 2009, volume 5 Issue: №3 Pages: 424-428
Heading: Urology Article type: Original article
Authors: O.S. Streltsova, V.N. Krupin, E.V. Zagaynova, E.A. Tararova, V.V. Klochay, E.B. Kiseleva
Organization: N. Novgorod State Medical Academy

The analysis of mucosa's state of the bladder in treating the exacerbation chronicle cystitis in 67 women was made. The analysis was made with the use of the method of optical coherent tomography (ОСТ). Dynamic ОСТ was performed in 23 patients after antibacterial treat (after 2 weeks) and in the period of remission. It was 59 ОСТ examinations. After antibacterial treatment the pathologically unchanged mucosa was found in the form of thickening in interu-retericfold in Lieutands triangle, in the neck of urinary bladder. Sub mucosal layer was also think, the structure of fibers was destroyed. Both leucocytic and lymphocytic infiltration in the wall of the bladder was observed. The tissue which reflected the light signal was found in muscle structure in the period of remission. This correspond to fibrosis in the wall of the bladder. In the long process the atrophy of mucosa was found. Thus, pathogenetic therapy should proceed after decrease in expressiveness of clinical displays of disease

Keywords: optical coherent tomography, chronic cystitis