Саратовский научно-медицинский ЖУРНАЛ

Методы неинвазивной оценки барьерных свойств кожи

Год: 2014, том 10 Номер: №3 Страницы: 512-517
Рубрика: Кожные болезни Тип статьи: Обзор
Авторы: Утц С.Р., Каракаева А.В., Галкина Е.М.
Организация: ФГБОУ ВО Саратовский ГМУ им. В.И. Разумовского Минздрава России
Резюме:

Кожа как покровный орган обладает множеством функций, самой главной из которых является защитная. Кожный покров — важный барьер на пути воды, белков и компонентов плазмы. Эпидермис представляет собой сложную структуру, его главным компонентом считается роговой слой, препятствующий проникновению экзогенных веществ через кожу. Эпидермальный барьер не является статичной структурой. Параметры проницаемости барьера могут быть изменены различными внешними и внутренними факторами, такими, как климатические условия, физические данные, и рядом кожных и системных заболеваний. Сегодня различные неинва-зивные подходы используются для мониторинга состояния кожного барьера in vivo. Количественное измерение кожных параметров, таких, как потеря трансэпидермальной воды, уровня гидратации, рН кожи, имеет важное значение для интегральной оценки состояния эпидермального барьера. В статье представлены неинвазивные методики исследования кожного барьера in vivo.

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