Saratov JOURNAL of Medical and Scientific Research

Diagnostic value of markers of vascular endothe-lial injury in thermal traumas

Year: 2011, volume 7 Issue: №3 Pages: 629-632
Heading: Clinical Laboratory Diagnostics Article type: Original article
Authors: Morrison V. V., Bozhedomov A. Yu., Zakharova N. В., Podgornova A. V.
Organization: Saratov City Clinical Hospital №7, Saratov State Medical University

The research goal is to study the composition of biological vascular endothelial injury markers in dynamic development of burn disease. Materials and methods: the investigation included 32 patients with thermal burns. The markers of vascular endothelial growth factor (VEGF), monocyte chemotactic protein-1 (MCP-1) and the number of circulating endothelial cells (CECs) were observed. Results: it was revealed that levels of VEGF, MCP-1 and CECs were significantly increased in patients with thermal traumas. Conclusion: VEGF and MCP-1 were proved to be early and prominent vascular endothelial injury markers in burn disease

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