Saratov JOURNAL of Medical and Scientific Research

Study of nerve fibers nature reinforcing duodenal contractions by electrical stimulation of sympathetic nerve

Year: 2011, volume 7 Issue: №3 Pages: 580-583
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Sveshnikov D.S., Kirichuk V.F., Smirnov V.M., Myasnikov I. L, Kuchuk A.M., Trofimova J.E., Trubetskaya M.A.
Organization: Saratov State Medical University, Russian State Medical University

The subject of the article is to investigate the mechanism of increased reactions by electrical stimulation of the sympathetic nerve. Materials and methods: Experiments on dogs have shown that stimulant reactions during blockade of a-adrenergic by phentolamine and (3-adrenergic receptors with propranolol were completely eliminated by lizer-gol —the blocker of 5-HT12-receptors. Results: Infusion of lizergol did not influence on duodenal motor activity and the function of the vagus nerve. Conclusion: Effector neuron is found out to be serotonergic and its action is provided by 5-HT1 2 receptors

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